Hydrocortisone IMpurity I

Product Name: Hydrocortisone IMpurity I
CAS No.: 103795-84-2
Chemical Name: Hydrocortisone IMpurity I
Synonyms: 14α-Hydroxyhydrocortisone;Hydrocortisone IMpurity I;Hydrocortisone EP Impurity I;Hydrocortisone impurity I (EP);11β,14,17,21-tetrahydroxypregn-4-ene-3,20-dione;Hydrocortisone Impurity 9（Hydrocortisone EP Impurity I）;Pregn-4-ene-3,20-dione, 11,14,17,21-tetrahydroxy-, (11β)-;(8R,9S,10R,11S,13S,14R,17R)-11,14,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one (Hydrocortisone Impurity)
CBNumber: CB42674445
Molecular Formula: C21H30O6
Formula Weight: 378.46
MOL File: 103795-84-2.mol

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Hydrocortisone IMpurity I Property

Melting point:: 241-242 °C
Boiling point:: 602.3±55.0 °C(Predicted)
Density: 1.35±0.1 g/cm3(Predicted)
pka: 12.10±0.70(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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Hydrocortisone IMpurity I Chemical Properties,Usage,Production

Uses

14α-Hydroxycortisol (Hydrocortisone EP Impurity I) is an impurity of Hydrocortisone (H714615), a topical corticosteroid (1), but more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland (2). Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.

Hydrocortisone IMpurity I Preparation Products And Raw materials

Raw materials

Preparation Products

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Hydrocortisone IMpurity I Suppliers

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103795-84-2, Hydrocortisone IMpurity IRelated Search:

Hydrocortisone-17-butyrate Hydrocortisone 11-ALPHA-HYDROCORTISONE Hydrocortisone IMpurity N IMp. B (EP): 17,21-Dihydroxypregn-4-ene-3,11,20-trione (Cortisone) IMp. C (EP): Hydrocortisone Acetate(Hydrocortisone 21-Acetate) IMp. A (EP): Prednisolone IMp. F (EP): 17,21-Dihydroxypregn-4-ene-3,20-dione(Reichstein's Substance S) Hydrocortisone IMpurity H IMp. E (EP): 11b,17,21-Trihydroxypregna-4,6-diene-3,20-dione(D6-Hydrocortisone) IMp. D (EP): 6b,11b,17,21-Tetrahydroxypregn-4-ene-3,20-dione(6b-Hydroxyhydrocortisone) Hydrocortisone IMpurity O

Hydrocortisone IMpurity I

11β,14,17,21-tetrahydroxypregn-4-ene-3,20-dione

Hydrocortisone EP Impurity I

Hydrocortisone impurity I (EP)

Hydrocortisone Impurity 9（Hydrocortisone EP Impurity I）

Pregn-4-ene-3,20-dione, 11,14,17,21-tetrahydroxy-, (11β)-

14α-Hydroxyhydrocortisone

(8R,9S,10R,11S,13S,14R,17R)-11,14,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one (Hydrocortisone Impurity)

103795-84-2