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Hydrocortisone IMpurity I

Product Name
Hydrocortisone IMpurity I
CAS No.
103795-84-2
Chemical Name
Hydrocortisone IMpurity I
Synonyms
14α-Hydroxyhydrocortisone;Hydrocortisone IMpurity I;Hydrocortisone EP Impurity I;Hydrocortisone impurity I (EP);11β,14,17,21-tetrahydroxypregn-4-ene-3,20-dione;Hydrocortisone Impurity 9(Hydrocortisone EP Impurity I);Pregn-4-ene-3,20-dione, 11,14,17,21-tetrahydroxy-, (11β)-;(8R,9S,10R,11S,13S,14R,17R)-11,14,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one (Hydrocortisone Impurity)
CBNumber
CB42674445
Molecular Formula
C21H30O6
Formula Weight
378.46
MOL File
103795-84-2.mol
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Hydrocortisone IMpurity I Property

Melting point:
241-242 °C
Boiling point:
602.3±55.0 °C(Predicted)
Density 
1.35±0.1 g/cm3(Predicted)
pka
12.10±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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Hydrocortisone IMpurity I Chemical Properties,Usage,Production

Uses

14α-Hydroxycortisol (Hydrocortisone EP Impurity I) is an impurity of Hydrocortisone (H714615), a topical corticosteroid (1), but more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland (2). Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.

Hydrocortisone IMpurity I Preparation Products And Raw materials

Raw materials

Preparation Products

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Hydrocortisone IMpurity I Suppliers

Pharma Affiliates
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Anant Pharmaceuticals Pvt. ltd
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SynZeal Research Pvt Ltd
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standards@synzeal.com
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Pharmaffiliates Analytics and Synthetics P. Ltd
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103795-84-2, Hydrocortisone IMpurity IRelated Search:


  • Hydrocortisone IMpurity I
  • 11β,14,17,21-tetrahydroxypregn-4-ene-3,20-dione
  • Hydrocortisone EP Impurity I
  • Hydrocortisone impurity I (EP)
  • Hydrocortisone Impurity 9(Hydrocortisone EP Impurity I)
  • Pregn-4-ene-3,20-dione, 11,14,17,21-tetrahydroxy-, (11β)-
  • 14α-Hydroxyhydrocortisone
  • (8R,9S,10R,11S,13S,14R,17R)-11,14,17-Trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one (Hydrocortisone Impurity)
  • 103795-84-2