PSI-7976

ChemicalBook > CAS DataBase List > PSI-7976

Product Name: PSI-7976
CAS No.: 1190308-01-0
Chemical Name: PSI-7976
Synonyms: PSI-7976;SFB-L-ALANITE-MODEL;SFB-L-Alaninate-Model;Sofosbuvir (R)-Phosphate;Sofosbuvir phosphate salt;(R)-(((2R,3R,4R,5R)-L-Sofosbuvir Isomer(Sofosbuvir INT Impurity A);N-[[P(R),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-methylethyl ester;L-Alanine, N-[[P(R),2'R]-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-, 1-methylethyl ester;isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alanite;isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-Lalaninate
CBNumber: CB42685935
Molecular Formula: C22H29FN3O9P
Formula Weight: 529.45
MOL File: 1190308-01-0.mol

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PSI-7976 Property

Melting point:: 76-82°C
Density: 1.41±0.1 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: Chloroform (Slightly), DMSO (Slightly), Ethyl Aceatae (Slightly)
pka: 9.39±0.10(Predicted)
form: Solid
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: S675615
Product name: Sofosbuvir(R)-Phosphate
Packaging: 2.5mg
Price: $340
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 67032
Product name: Sofosbuvir(R)-Phosphate
Packaging: 2.5mg
Price: $650
Updated: 2021/12/16

ChemScene

Product number: CS-2405
Product name: PSI-7976
Purity: 98.24%
Packaging: 1mg
Price: $1800
Updated: 2021/12/16

ChemScene

Product number: CS-2405
Product name: PSI-7976
Purity: 98.24%
Packaging: 5mg
Price: $4200
Updated: 2021/12/16

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PSI-7976 Chemical Properties,Usage,Production

Uses

Sofosbuvir (R)-Phosphate is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

PSI-7976 Preparation Products And Raw materials

Raw materials

Preparation Products

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1190308-01-0, PSI-7976Related Search:

GAMMA-CYHALOTHRIN Sofosbuvir metabolites Cytidine,N-benzoyl-2^-C-Methyl-,3^,5^-dibenzoate(9CI) PSI-7977-13C-d3 Sofosbuvir SofosBuvir impurity 45 SofosBuvir Impurity 53 sofosBuvir Impurity 37 PSI 7411 Sofosbuvir Impurity 6 1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione Sofosbuvir Impurity27 SofosBuvir Impurity 38 Sofosbuvir impurity I (2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate Sofosbuvir impurity D SofosBuvir Impurity 31 sofosBuvir Impurity 33

PSI-7976

N-[[P(R),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-methylethyl ester

Sofosbuvir (R)-Phosphate

(S)-isopropyl 2-((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propanoate

isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-Lalaninate

L-Alanine, N-[[P(R),2'R]-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-, 1-methylethyl ester

isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alanite

Sofosbuvir impurity 14/ RP-Isomer of Sofosbuvir/Isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate

Sofosbuvir phosphate salt

SFB-L-Alaninate-Model

Sofosbuvir L-alanitate (Mixture of Diasteriomers)Q: What is Sofosbuvir L-alanitate (Mixture of Diasteriomers) Q: What is the CAS Number of Sofosbuvir L-alanitate (Mixture of Diasteriomers) Q: What is the storage condition of Sofosbuvir L-alanitate (Mixture of Diasteriomers) Q: What are the applications of Sofosbuvir L-alanitate (Mixture of Diasteriomers)

SFB-L-ALANITE-MODEL

(R)-(((2R,3R,4R,5R)-L-Sofosbuvir Isomer(Sofosbuvir INT Impurity A)

1190308-01-0

190308-01-0