ChemicalBook > CAS DataBase List > PSI-7977-13C-d3

PSI-7977-13C-d3

Product Name
PSI-7977-13C-d3
CAS No.
2070009-25-3
Chemical Name
PSI-7977-13C-d3
Synonyms
PSI-7977-13C-d3;[13C,2H3]-Sofosbuvir;isopropyl((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-(methyl-13C-d3)tetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate;Sofosbuvir 13CD3Q: What is Sofosbuvir 13CD3 Q: What is the CAS Number of Sofosbuvir 13CD3 Q: What is the storage condition of Sofosbuvir 13CD3 Q: What are the applications of Sofosbuvir 13CD3
CBNumber
CB64666758
Molecular Formula
C2113CH26D3FN3O9P
Formula Weight
0
MOL File
Mol file
More
Less

PSI-7977-13C-d3 Property

storage temp. 
Store at -20°C
solubility 
DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 0.2 mg/ml
form 
A solid
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
25045
Product name
PSI-7977-13C-d3
Purity
≥99% deuterated forms (d1-d3)
Packaging
1mg
Price
$456
Updated
2024/03/01
Usbiological
Product number
463192
Product name
PSI-7977-13CD3
Packaging
1mg
Price
$531
Updated
2021/12/16
TRC
Product number
P839642
Product name
PSI-7977-13CD3
Packaging
1mg
Price
$220
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
52859
Product name
PSI-7977-13CD3
Packaging
1mg
Price
$700
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
52859
Product name
PSI-7977-13CD3
Packaging
10mg
Price
$2600
Updated
2021/12/16
More
Less

PSI-7977-13C-d3 Chemical Properties,Usage,Production

Description

PSI-7977-13C-d3 is intended for use as an internal standard for the quantification of PSI-7977 by GC- or LC-MS. PSI-7977 is a phosphoramidate prodrug of PSI-7851, a nucleoside analog that, when phosphorylated, inhibits the RNA-dependent RNA polymerase of hepatitis C virus (EC50 = 92 nM). PSI-7977 is effective in vitro and in vivo.

Uses

PSI-7977-13CD3 is the isotope labelled analog of PSI-7977. PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

PSI-7977-13C-d3 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

PSI-7977-13C-d3 Suppliers

Artis Biotech Co. Ltd.
Tel
0575-18780151478 18582380095
Fax
0575-89298961
Email
sales@artisbio.com
Country
China
ProdList
2966
Advantage
58
ANHUI WITOP BIOTECH CO., LTD
Tel
+8615255079626
Email
eric@witopchemical.com
Country
China
ProdList
23541
Advantage
58
Shanghai Payne Pharmaceutical Technology Co.Ltd
Tel
021-58123769 17721400256
Email
info@paynepharm.com
Country
China
ProdList
1285
Advantage
58
Shanghai Payne Pharmaceutical Technology Co.Ltd
Tel
021-58123769 18678586262
Email
info@paynepharm.com
Country
China
ProdList
1354
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11974
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
17301488900
Fax
025-85560043
Email
judy.xia@synzest.com
Country
China
ProdList
12582
Advantage
58
Hubei Moco Chemical Co., Ltd.
Tel
18627753421 18627756402
Fax
QQ:3001051413
Email
3001009495@qq.com
Country
China
ProdList
19063
Advantage
58
United States Biological
Tel
--
Fax
--
Email
sales@advtechind.com
Country
United States
ProdList
6075
Advantage
58

2070009-25-3, PSI-7977-13C-d3Related Search:


  • [13C,2H3]-Sofosbuvir
  • isopropyl((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-(methyl-13C-d3)tetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
  • Sofosbuvir 13CD3Q: What is Sofosbuvir 13CD3 Q: What is the CAS Number of Sofosbuvir 13CD3 Q: What is the storage condition of Sofosbuvir 13CD3 Q: What are the applications of Sofosbuvir 13CD3
  • PSI-7977-13C-d3
  • 2070009-25-3
  • C2113CH26D3FN3O9P