ChemicalBook > CAS DataBase List > 2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid

2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid

Product Name
2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid
CAS No.
1330632-48-8
Chemical Name
2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid
Synonyms
Febuxostat-16;ZMFUVKAZLYEVBM-UHFFFAOYSA-N;Febuxostat Dithiazole Acid Impurity;2,2'-(4-Isobutoxy-1,3-phenylene)bis(4-methyl-1,3-thiazole-5-carboxylic acid);2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-methyl-5-thiazolecarboxylic Acid;5-Thiazolecarboxylic acid, 2,2'-[4-(2-methylpropoxy)-1,3-phenylene]bis[4-methyl-;Febuxostat Impurity 23/Febuxostat Dithiazole Acid Impurity/2,2'-(4-isobutoxy-1,3-phenylene)bis(4-methylthiazole-5-carboxylic acid)
CBNumber
CB42694926
Molecular Formula
C20H20N2O5S2
Formula Weight
432.51
MOL File
1330632-48-8.mol
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2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid Property

Boiling point:
703.6±70.0 °C(Predicted)
Density 
1.364±0.06 g/cm3(Predicted)
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
1.20±0.37(Predicted)
form 
Solid
color 
Off-White to Pale Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
M326845
Product name
2,2''-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-methyl-5-thiazolecarboxylicAcid
Packaging
25mg
Price
$165
Updated
2021/12/16
TRC
Product number
M326845
Product name
2,2''-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-methyl-5-thiazolecarboxylicAcid
Packaging
250mg
Price
$1100
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
52363
Product name
2,2??-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-methyl-5-thiazolecarboxylicAcid
Packaging
25mg
Price
$650
Updated
2021/12/16
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2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid Chemical Properties,Usage,Production

Uses

2,2''-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-methyl-5-thiazolecarboxylic Acid is an impurity of Febuxostat (F229000), which is an urate lowering drug, an inhibitor of xanthine oxidase that is indicated for use in the treatment of hyperuicemia and chronic gout.

Uses

2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-methyl-5-thiazolecarboxylic Acid is an impurity of Febuxostat (F229000), which is an urate lowering drug, an inhibitor of xanthine oxidase that is indicated for use in the treatment of hyperuicemia and chronic gout.

2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid Suppliers

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1330632-48-8, 2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic AcidRelated Search:

Febuxostat impurity 36 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylic acid 2-(4-HYDROXY-PHENYL)-4-METHYL-THIAZOLE-5-CARBOXYLIC ACID ethyl 2-(4-butoxy-3-formylphenyl)-4-methylthiazole-5- carboxylate FeBuxostat Impurity 32 2-(4-(sec-butoxy)-3-cyanophenyl)-4-methylthiazole-5-carboxylic acid Febuxostat Bromo Impurity Febuxostat Impurity 14 2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid ethyl 2-(4-butoxy-3-cyanophenyl)-4-methylthiazole-5- carboxylate FeBuxostat Impurity 18 ethyl 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5- carboxylate 2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid Febuxostat impurity 37 FeBuxostat Impurity 33 Febuxostat Descyano Impurity FeBuxostat Impurity 26 Febuxostat Acyl-β-D-glucuronide

  • Febuxostat Dithiazole Acid Impurity
  • ZMFUVKAZLYEVBM-UHFFFAOYSA-N
  • Febuxostat-16
  • Febuxostat Impurity 23/Febuxostat Dithiazole Acid Impurity/2,2'-(4-isobutoxy-1,3-phenylene)bis(4-methylthiazole-5-carboxylic acid)
  • 5-Thiazolecarboxylic acid, 2,2'-[4-(2-methylpropoxy)-1,3-phenylene]bis[4-methyl-
  • 2,2'-(4-Isobutoxy-1,3-phenylene)bis(4-methyl-1,3-thiazole-5-carboxylic acid)
  • 2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-methyl-5-thiazolecarboxylic Acid
  • 1330632-48-8
  • Aromatics, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds