ChemicalBook > CAS DataBase List > 2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid

2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid

Product Name
2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid
CAS No.
407582-48-3
Chemical Name
2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid
Synonyms
Febuxostat-19;Febuxostat-002;Hydroxy Febuxostat;Febuxostat Impurity T;Febuxostat Impurity R;Febuxostat Impurity 9;4-butoxyisophthalonitrile;2-(3-cyano-4-hydroxyphenyl);2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid;2-(3-Cyano-4-hydroxyphenyl)-4-methyl-5-thiazolecarboxylic acid
CBNumber
CB43146798
Molecular Formula
C12H8N2O3S
Formula Weight
260.27
MOL File
407582-48-3.mol
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2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid Property

Boiling point:
541.8±60.0 °C(Predicted)
Density 
1.56±0.1 g/cm3(Predicted)
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
2.22±0.37(Predicted)
form 
Solid
color 
Off-White to Light Yellow
Stability:
Light Sensitive
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
D291100
Product name
DesisobutylFebuxostat
Packaging
500mg
Price
$510
Updated
2021/12/16
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2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid Chemical Properties,Usage,Production

Uses

Desisobutyl Febuxostat is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor that is used for treating hyperuricemia and chronic gout.

2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid Suppliers

China 52 India 6 United Kingdom 1 United States 4 Global 63
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407582-48-3, 2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acidRelated Search:

Febuxostat 4-(2-Methylpropoxy)-1,3-benzenedicarbothioaMide 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylic acid 2-(4-HYDROXY-PHENYL)-4-METHYL-THIAZOLE-5-CARBOXYLIC ACID ethyl 2-(4-butoxy-3-formylphenyl)-4-methylthiazole-5- carboxylate FeBuxostat Impurity 32 2-(4-(sec-butoxy)-3-cyanophenyl)-4-methylthiazole-5-carboxylic acid Febuxostat Bromo Impurity Febuxostat Impurity 14 2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid ethyl 2-(4-butoxy-3-cyanophenyl)-4-methylthiazole-5- carboxylate FeBuxostat Impurity 18 ethyl 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5- carboxylate 2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid Febuxostat impurity 37 FeBuxostat Impurity 33 Febuxostat Descyano Impurity FeBuxostat Impurity 26

  • 2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid
  • Febuxostat Impurity 9
  • Febuxostat Impurity R
  • Febuxostat Impurity T
  • Febuxostat-19
  • 2-(3-cyano-4-hydroxyphenyl)
  • Febuxostat impurity 2/Febuxostat 4-Hydroxy Acid/2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid
  • Febuxostat-002
  • 2-(3-cyano-4-oxocyclohexa-2,5-dien-1-ylidene)-4-methyl-3H-1,3-thiazole-5-carboxylic acid
  • 4-butoxyisophthalonitrile
  • Hydroxy Febuxostat
  • 5-Thiazolecarboxylic acid, 2-(3-cyano-4-hydroxyphenyl)-4-methyl-
  • 2-(3-Cyano-4-hydroxyphenyl)-4-methyl-5-thiazolecarboxylic acid
  • Hydroxy FebuxostatQ: What is Hydroxy Febuxostat Q: What is the CAS Number of Hydroxy Febuxostat Q: What is the storage condition of Hydroxy Febuxostat Q: What are the applications of Hydroxy Febuxostat
  • 2-(3-Cyano-4-hydroxyphenyl)-4-methyl-5-thiazolecarboxylic Acid (Desisobutylfebuxostat)
  • 407582-48-3