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GerMicidin A

Product Name
GerMicidin A
CAS No.
150973-78-7
Chemical Name
GerMicidin A
Synonyms
GerMicidin A;2H-Pyran-2-one, 3-ethyl-4-hydroxy-6-(1-methylethyl)-
CBNumber
CB42703734
Molecular Formula
C10H14O3
Formula Weight
182.22
MOL File
150973-78-7.mol
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GerMicidin A Property

Boiling point:
283.6±40.0 °C(Predicted)
Density 
1.130±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
solid
pka
5.36±0.50(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
20591
Product name
Germicidin B
Purity
≥95%
Packaging
500 μg
Price
$175
Updated
2024/03/01
Cayman Chemical
Product number
19971
Product name
Germicidin A
Purity
≥95%
Packaging
1mg
Price
$220
Updated
2024/03/01
Cayman Chemical
Product number
19971
Product name
Germicidin A
Purity
≥95%
Packaging
5mg
Price
$984
Updated
2024/03/01
Cayman Chemical
Product number
20591
Product name
Germicidin B
Purity
≥95%
Packaging
1mg
Price
$205
Updated
2022/04/27
Cayman Chemical
Product number
20591
Product name
Germicidin B
Purity
≥95%
Packaging
5mg
Price
$946
Updated
2022/04/27
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GerMicidin A Chemical Properties,Usage,Production

Description

Germicidin A is a pyranone originally derived from S. viridochromogenes that acts as a reversible, autoregulative inhibitor of spore germination and hyphal elongation in the genus Streptomyces at concentrations as low as 200 pM. During germination, spores of Streptomyces excrete germicidin A along with other germicidin homologs, which inhibit germination of its own arthrospores. At higher concentrations, germicidin A can inhibit the porcine Na+/K+-activated ATPase (ID50 = 100 μM) and prevent the germination of the cress L. sativum.

Uses

Germicidin A is a pyranone isolated from Streptomyces sp. in 1993. Germicidin A is an extremely potent autoregulator of the sporulation of the producing strain, and spores of closely related species. Inhibition is detected at 0.1 ng/ml and is orders of magnitude more potent than a diverse range of antibiotics.

Uses

Germicidin A is an extremely potent autoregulator.

References

[1] petersen f, zhner h, metzger j w, et al. germicidin, an autoregulative germination inhibitor of streptomyces viridochromogenes nrrl b-1551[j]. the journal of antibiotics, 1993, 46(7): 1126-1138.
[2] aoki y, matsumoto d, kawaide h, et al. physiological role of germicidins in spore germination and hyphal elongation in streptomyces coelicolor a3 (2)[j]. the journal of antibiotics, 2011, 64(9): 607-611.

GerMicidin A Preparation Products And Raw materials

Raw materials

Preparation Products

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GerMicidin A Suppliers

Novachemistry
Tel
44-20819178-90 02081917890
Fax
(0)2080432064
Email
info@novachemistry.com
Country
United Kingdom
ProdList
4381
Advantage
58

150973-78-7, GerMicidin ARelated Search:


  • GerMicidin A
  • 2H-Pyran-2-one, 3-ethyl-4-hydroxy-6-(1-methylethyl)-
  • 150973-78-7