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para-Hydroxy Atorvastatin CalciuM Salt

Product Name
para-Hydroxy Atorvastatin CalciuM Salt
CAS No.
265989-44-4
Chemical Name
para-Hydroxy Atorvastatin CalciuM Salt
Synonyms
Amlodipine Impurity 88;4-Hydroxy Atorvastatin;Atorvastatin Impurity J;Atorvastatin Impurity 52;Atorvastatin Impurity 154;Para-Hydroxy Atorvastatin Calcium;4-Hydroxy Atorvastatin HeMicalciuM Salt;calcium,(3S,5S)-7-[2-(4-fluorophenyl)-4-[(4-hydroxyphenyl)carbamoyl]-3-phenyl-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate;Atorvastatin impurity 35/para-Hydroxy Atorvastatin Calcium Salt/(3R,5R)-7-[2-(4-fluorophenyl)-4-[(4-hydroxyphenyl)carbamoyl]-3-phenyl-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate Calcium Salt;4-Hydroxy-Atorvastatin calcium saltQ: What is 4-Hydroxy-Atorvastatin calcium salt Q: What is the CAS Number of 4-Hydroxy-Atorvastatin calcium salt Q: What is the storage condition of 4-Hydroxy-Atorvastatin calcium salt Q: What are the applications of 4-Hydroxy-Atorvastatin calcium salt
CBNumber
CB42707055
Molecular Formula
C66H70CaF2N4O12
Formula Weight
1189.3564064
MOL File
265989-44-4.mol
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para-Hydroxy Atorvastatin CalciuM Salt Property

storage temp. 
Store at -20°C
solubility 
DMF: 25 mg/ml; DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml; DMSO: 15 mg/ml; Ethanol: 0.5 mg/ml
form 
A crystalline solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22575
Product name
4-hydroxy Atorvastatin (calcium salt)
Purity
≥90%
Packaging
500μg
Price
$81
Updated
2024/03/01
Cayman Chemical
Product number
22575
Product name
4-hydroxy Atorvastatin (calcium salt)
Purity
≥90%
Packaging
1mg
Price
$152
Updated
2024/03/01
Cayman Chemical
Product number
22575
Product name
4-hydroxy Atorvastatin (calcium salt)
Purity
≥90%
Packaging
5mg
Price
$515
Updated
2024/03/01
Medical Isotopes, Inc.
Product number
4857
Product name
p-Hydroxyatorvastatincalciumsalt
Purity
98%
Packaging
1mg
Price
$590
Updated
2021/12/16
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para-Hydroxy Atorvastatin CalciuM Salt Chemical Properties,Usage,Production

Description

4-hydroxy Atorvastatin is a metabolite of atorvastatin , an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.1,2,3,4 Atorvastatin is metabolized by the cytochrome P450 (CYP) isoform CYP3A4 to form 4-hydroxy atorvastatin.1

References

1. Hong, J.H., Youm, J.K., Kwon, M.J., et al. K6PC-5, a direct activator of sphingosine kinase 1, promotes epidermal differentiation through intracellular Ca2+ signaling J. Invest. Dermatol. 128,2166-2178(2008).
2. Dart, A., Jerums, G., Nicholson, G., et al. A multicenter, double-blind, one-year study comparing safety and efficacy of atorvastatin versus simvastatin in patients with hypercholesterolemia Am. J. Cardiol. 80(1),39-44(1997).
3. Group, T.D.A.L.I.S. The effect of aggressive versus standard lipid lowering by atorvastatin on diabetic dyslipidemia. The DALI study: A double-blind, randomized, placebo-controlled trial in patients with type 2 diabetes and diabetic dyslipidemia Diabetes Care 24(8),1335-1341(2001).
4. van Dam, M., Zwart, M., de Beer, F., et al. Long term efficacy and safety of atorvastatin in the treatment of severe type III and combined dyslipidaemia Heart 88(3),234-238(2002).

para-Hydroxy Atorvastatin CalciuM Salt Preparation Products And Raw materials

Raw materials

Preparation Products

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para-Hydroxy Atorvastatin CalciuM Salt Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14059
Advantage
65
Cato Research Chemicals Inc.
Tel
020-81960175
Fax
+1-541-2553641
Email
min.he@cato-chem.com
Country
China
ProdList
1958
Advantage
55
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17981
Advantage
56
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9636
Advantage
58
Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-58362220 15250997978
Fax
025-58362220
Email
1511893459@qq.com
Country
China
ProdList
7730
Advantage
55
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9926
Advantage
65
ShangHai Biochempartner Co.,Ltd
Tel
17754423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8003
Advantage
62
Roark Standards
Tel
0755-83552066 15986688328
Fax
0755-83552066
Email
service@roarkstandards.com
Country
China
ProdList
1443
Advantage
58
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View Lastest Price from para-Hydroxy Atorvastatin CalciuM Salt manufacturers

Hangzhou Huarong Pharm Co., Ltd.
Product
Para-Hydroxy Atorvastatin Calcium Salt 265989-44-4
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
99%
Supply Ability
10KG
Release date
2021-09-17

265989-44-4, para-Hydroxy Atorvastatin CalciuM SaltRelated Search:


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  • Atorvastatin Impurity 52
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  • 4-Hydroxy Atorvastatin
  • Atorvastatin Impurity J
  • Para-Hydroxy Atorvastatin Calcium
  • Atorvastatin Impurity 154
  • calcium,(3S,5S)-7-[2-(4-fluorophenyl)-4-[(4-hydroxyphenyl)carbamoyl]-3-phenyl-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate
  • 4-Hydroxy-Atorvastatin calcium saltQ: What is 4-Hydroxy-Atorvastatin calcium salt Q: What is the CAS Number of 4-Hydroxy-Atorvastatin calcium salt Q: What is the storage condition of 4-Hydroxy-Atorvastatin calcium salt Q: What are the applications of 4-Hydroxy-Atorvastatin calcium salt
  • Amlodipine Impurity 88
  • 265989-44-4