Optovin
- Product Name
- Optovin
- CAS No.
- 348575-88-2
- Chemical Name
- Optovin
- Synonyms
- CS-1131;Optovin;Oprovin;Optovin (mixture of isomers);5-[[2,5-dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-2-thioxo-4-thiazolidinone;5-((2,5-Dimethyl-1-(pyridin-3-yl)-1H-pyrrol-3-yl)methylene)-2-thioxothiazolidin-4-one;4-Thiazolidinone, 5-[[2,5-dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-2-thioxo-
- CBNumber
- CB42708133
- Molecular Formula
- C15H13N3OS2
- Formula Weight
- 315.41
- MOL File
- 348575-88-2.mol
Optovin Property
- Density
- 1.38±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Soluble in DMSO (up to 30 mg/ml)
- pka
- 7.65±0.50(Predicted)
- form
- solid
- color
- Tan
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 14851
- Product name
- Optovin
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $81
- Updated
- 2024/03/01
- Product number
- 14851
- Product name
- Optovin
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $152
- Updated
- 2024/03/01
- Product number
- 14851
- Product name
- Optovin
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $317
- Updated
- 2024/03/01
- Product number
- 14851
- Product name
- Optovin
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $553
- Updated
- 2024/03/01
- Product number
- 4901
- Product name
- Optovin
- Purity
- ≥99%(HPLC)
- Packaging
- 50
- Price
- $767
- Updated
- 2021/12/16
Optovin Chemical Properties,Usage,Production
Description
Optovin (348575-88-2) is a reversible photoactive TRPA1 activator. Optovin stimulates human TRPA1 channels and enables repeated photoactivation of motor behaviors in wild-type zebrafish (EC50?= 2 μM) and mice,?in vivo. Photodetection is performed by sensory neurons expressing the TRPA1 cation channel which is activated via structure-dependent photochemical reactions with redox-sensitive cysteine residues.1
Uses
Optovin activates human TRPA1 via structure-dependent photochemistry.
Definition
ChEBI: Optovin is a member of the class of thiazolidinone that is rhodanine in which the two methylene hydrogens have been replaced by a 2,5-dimethyl-1-(pyridin-3-yl)-1H-pyrrol-3-yl]methylidene group. A TRPA1 ligand that can be reversibly photoactivated. It has a role as a TRPA1 channel agonist. It is a member of pyrroles, a member of pyridines, an olefinic compound and a thiazolidinone. It is functionally related to a rhodanine.
storage
Store at +4°C
References
1) Kokel?et al. (2013),?Photochemical activation of TRPA1 channels in neurons and animals; Nat. Chem. Biol.,?9?257
Optovin Preparation Products And Raw materials
Raw materials
Preparation Products
Optovin Suppliers
View Lastest Price from Optovin manufacturers
- Product
- Optovin 348575-88-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- Optovin 348575-88-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- 4-?Thiazolidinone, 5-?[[2,?5-?dimethyl-?1-?(3-?pyridinyl)?-?1H-?pyrrol-?3-?yl]?methylene]?-?2-?thioxo- 348575-88-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- Min98% HPLC
- Supply Ability
- g/kg/ton
- Release date
- 2019-12-23