ChemicalBook > CAS DataBase List > MK-4827 (R-enantioMer)
MK-4827 (R-enantioMer)
- Product Name
- MK-4827 (R-enantioMer)
- CAS No.
- 1038915-58-0
- Chemical Name
- MK-4827 (R-enantioMer)
- Synonyms
- (R)-Niraparib;ent-Niraparib;ent-Nirapanib;Niraparib Impurity;Niraparib Impurity 13;Niraparib Impurity 51;MK-4827 (R-enantioMer);Niraparib R-enantiomer;R isomer of MK-4827, Niraparib;(R)-2-(4-(PIPERIDIN-3-YL)PHENYL)-2H-INDAZOLE-7-CARBOXAMIDE
- CBNumber
- CB42716288
- Molecular Formula
- C19H20N4O
- Formula Weight
- 320.39
- MOL File
- 1038915-58-0.mol
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MK-4827 (R-enantioMer) Property
- Boiling point:
- 463.6±45.0 °C(Predicted)
- Density
- 1.34±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : ≥ 32 mg/mL (99.88 mM)
- pka
- 15.36±0.30(Predicted)
- form
- Solid
- color
- Light yellow to yellow
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N-Bromosuccinimide Price
TRC
- Product number
- N481410
- Product name
- ent-Niraparib
- Packaging
- 500mg
- Price
- $2230
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-3085
- Product name
- NiraparibR-enantiomer
- Purity
- 99.50%
- Packaging
- 5mg
- Price
- $220
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-3085
- Product name
- NiraparibR-enantiomer
- Purity
- 99.50%
- Packaging
- 10mg
- Price
- $380
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-3085
- Product name
- NiraparibR-enantiomer
- Purity
- 99.50%
- Packaging
- 50mg
- Price
- $990
- Updated
- 2021/12/16
Crysdot
- Product number
- CD00013477
- Product name
- (R)-2-(4-(Piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide
- Purity
- 97%
- Packaging
- 1g
- Price
- $3294
- Updated
- 2021/12/16
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MK-4827 (R-enantioMer) Chemical Properties,Usage,Production
Uses
ent-Niraparib is an isomer of Niraparib (N481400), a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors.
Definition
ChEBI: 2-{4-[(3R)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide is a 2-[4-(piperidin-3-yl)phenyl]-2H-indazole-7-carboxamide that has R-configuration. It is a potent PARP1 inhibitor with IC50 of 2.4 nM. It has a role as an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor and an antineoplastic agent.
MK-4827 (R-enantioMer) Preparation Products And Raw materials
Raw materials
Preparation Products
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MK-4827 (R-enantioMer) Suppliers
- Tel
- --
- Fax
- --
- mktg@pharmaffiliates.com
- Country
- India
- ProdList
- 6739
- Advantage
- 58
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View Lastest Price from MK-4827 (R-enantioMer) manufacturers
ShenZhen H&D Pharmaceutical Technology Co., LTD
- Product
- (R)-Niraparib 1038915-58-0
- Price
- US $0.00-0.00/mg
- Min. Order
- 10mg
- Purity
- 0.98
- Supply Ability
- 10g
- Release date
- 2024-05-07
1038915-58-0, MK-4827 (R-enantioMer)Related Search:
Niraparib
Niraparib tosylate
MK-4827 (tosylate)
(S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxaMide