ChemicalBook > CAS DataBase List > N-Methyl-N-((3R,4R)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine dihydrochloride
N-Methyl-N-((3R,4R)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine dihydrochloride
- Product Name
- N-Methyl-N-((3R,4R)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine dihydrochloride
- CAS No.
- 1260590-51-9
- Chemical Name
- N-Methyl-N-((3R,4R)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine dihydrochloride
- Synonyms
- N-Methyl-N-((3R,4R);-4-methylpiperidin-3-yl);N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin;N-METHYL-N-((3R,4R)-4-METHYLPIPERIDIN-3-YL)-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE HCL;N-Methyl-N-((3R,4R)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine 2HCl;N-Methyl-N-[(3R,4R)-4-methyl-3-piperidyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine Hydrochloride;N-Methyl-N-[(3R,4R)-4-methyl-3-piperidyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine x hydrochloride;N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine hydrochloride;N-Methyl-N-((3R,4R)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine dihydrochloride;N-Methyl-N-((3R,4R)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-amine dihydrochloride (N-1 HCl)
- CBNumber
- CB42718116
- Molecular Formula
- C13H20ClN5
- Formula Weight
- 281.79
- MOL File
- 1260590-51-9.mol
More
Less
N-Methyl-N-((3R,4R)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine dihydrochloride Property
- Melting point:
- >225°C (dec.)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Aqueous Acid (Slightly, Sonicated), Aqueous Base (Slightly), Water (Slightly)
- form
- Solid
- color
- White to Off-White
More
Less
N-Bromosuccinimide Price
TRC
- Product number
- M203523
- Product name
- N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-Pyrrolo[2,3-d]pyrimidin-4-amineHydrochloride
- Packaging
- 100mg
- Price
- $70
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-B0707
- Product name
- N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-aminedihydrochloride
- Purity
- 99.99%
- Packaging
- 1g
- Price
- $350
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-B0707
- Product name
- N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-aminedihydrochloride
- Purity
- 99.99%
- Packaging
- 5g
- Price
- $750
- Updated
- 2021/12/16
Ambeed
- Product number
- A172604
- Product name
- N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-aminehydrochloride
- Purity
- 97%
- Packaging
- 100mg
- Price
- $19
- Updated
- 2021/12/16
Ambeed
- Product number
- A172604
- Product name
- N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-aminehydrochloride
- Purity
- 97%
- Packaging
- 250mg
- Price
- $26
- Updated
- 2021/12/16
More
Less
N-Methyl-N-((3R,4R)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine dihydrochloride Chemical Properties,Usage,Production
Synthesis
Add TFTB-1, sodium hydroxide, ethanol and water to a 20L reaction flask, heat to 85 ° C, and keep the reaction for 3 hours. At the end of the reaction, vacuum distillation at 80-90 ° C until no liquid flows out. Add purified water and continue stirring. The mixture was cooled to room temperature, extracted with dichloromethane, and the aqueous layer was extracted with methylene chloride. The organic layer was combined, and the organic layer was washed with purified water. Filtration, evaporation of the filtrate, addition of acetone, reflux for 30 min, cooling to 20 ° C, filtration, filter cake into a dry box, drying at 60 ° C ± 5 ° C for 4 h, to obtain a white solid, that is, TFTB-2, yield 86%.
Uses
N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-Pyrrolo[2,3-d]pyrimidin-4-amine Hydrochloride, is a substance used in the identification of related substances in the degradation products of tofacitinib citrate using LC-MS technique for process monitoring and quality assurance. A reagent for the synthesis of Tofacitinib (CP-690,550), a Janus tyrosine kinase (JAK3) specific inhibitor.
Application
N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a substance used in the identification of related substances in the degradation products of tofacitinib citrate using LC-MS technique for process monitoring and quality assurance. A reagent for the synthesis of Tofacitinib (CP-690,550), a Janus tyrosine kinase (JAK3) specific inhibitor.
N-Methyl-N-((3R,4R)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
N-Methyl-N-((3R,4R)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine dihydrochloride Suppliers
- Tel
- 18189674620
- 761137152@qq.com
- Country
- China
- ProdList
- 489
- Advantage
- 55
- Tel
- 021-34975603-808 18721111801
- Fax
- +86-21-34975602-805
- sales@bocpharma.com
- Country
- China
- ProdList
- 997
- Advantage
- 64
- Tel
- 18601331139
- Fax
- QQ:3454155726
- BD@chempion.com.cn
- Country
- China
- ProdList
- 138
- Advantage
- 58
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42958
- Advantage
- 64
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 41462
- Advantage
- 60
- Tel
- 20-66003216 18666003216
- Fax
- +86-20-28069063
- info@porsefinechemical.com
- Country
- China
- ProdList
- 2353
- Advantage
- 62
- Tel
- 025-57018978 18251899859
- Fax
- 025-57018008
- sales@chalf-pharm.com
- Country
- China
- ProdList
- 5798
- Advantage
- 50
- Tel
- 18101936766
- Fax
- 021-58583907
- eileen@shmychem.com
- Country
- China
- ProdList
- 350
- Advantage
- 55
- Tel
- 15902145085
- Fax
- -
- 657990292@qq.com
- Country
- China
- ProdList
- 668
- Advantage
- 50
- Tel
- 13764913901
- Fax
- -
- info@angtibio.com
- Country
- China
- ProdList
- 5037
- Advantage
- 55
- Tel
- +86-010-60279497 +86-15646567669
- Fax
- 010-60279497
- sales01@cooperate-pharm.com
- Country
- China
- ProdList
- 137
- Advantage
- 58
- Tel
- 0317-5296180 15533709196
- Fax
- 0317-5106596
- sale@enkepharma.com
- Country
- China
- ProdList
- 1938
- Advantage
- 55
- Tel
- 177-54423994 17754423994
- Fax
- QQ:2853530913
- 2853530910@QQ.com
- Country
- China
- ProdList
- 8011
- Advantage
- 62
- Tel
- Fax
- -
- 13006575422@163.com
- Country
- China
- ProdList
- 6355
- Advantage
- 58
- Tel
- 0371-0371-55629727 13323845623
- Fax
- 037155629727
- 2885676761@qq.com
- Country
- China
- ProdList
- 9993
- Advantage
- 58
- Tel
- 0512-56316828
- Fax
- 0512-56316826
- info@amateksci.com
- Country
- China
- ProdList
- 28806
- Advantage
- 58
- Tel
- 400-711-5280 86-571-81025280
- Fax
- 86-571-85806285
- sales@molcore.com
- Country
- China
- ProdList
- 9967
- Advantage
- 58
- Tel
- +86-（0）57185586718 +86-13336195806
- Fax
- +86-571-85864795
- sales@capot.com
- Country
- China
- ProdList
- 29793
- Advantage
- 60
- Tel
- 025-66028182 18112977050
- Fax
- (3)02557626880
- cfzhang@aikonchem.com
- Country
- China
- ProdList
- 15818
- Advantage
- 58
- Tel
- 400-8210725 18016230971
- Fax
- 021-58955996
- malulu@leyan.com
- Country
- China
- ProdList
- 25004
- Advantage
- 58
- Tel
- 021-58958002 18930822973
- Fax
- 021-58958618
- sales@uhnshanghai.com
- Country
- China
- ProdList
- 1942
- Advantage
- 58
- Tel
- 021-68900963 15618693615
- Fax
- 021-68900963
- sales@jinghaopharma.com
- Country
- China
- ProdList
- 289
- Advantage
- 58
- Tel
- 4009004166/18616739031 18616739031
- 3007523370@qq.com
- Country
- China
- ProdList
- 52693
- Advantage
- 58
- Tel
- meitaochem@126.com
- meitaochem@126.com
- Country
- China
- ProdList
- 19103
- Advantage
- 58
- Tel
- +86-0551-65418684 +8618949823763
- Fax
- 0086-551-65418684
- sales@tnjchem.com
- Country
- China
- ProdList
- 25356
- Advantage
- 58
- Tel
- +8615056975894
- Fax
- 86-0551-62678551
- shawn@hirisunpharm.com
- Country
- CHINA
- ProdList
- 9911
- Advantage
- 58
- Tel
- 86-21-51086038
- Fax
- 86-21-51861608
- chemwill_asia@126.com
- Country
- CHINA
- ProdList
- 23912
- Advantage
- 58
- Tel
- 021-13773155751 19975051755
- 260924549@qq.com
- Country
- China
- ProdList
- 8913
- Advantage
- 58
- Tel
- +86-023-6139-8061 +86-86-13650506873
- sales@chemdad.com
- Country
- China
- ProdList
- 39894
- Advantage
- 58
- Tel
- +86-21-68900963
- Fax
- +86-21-68900963
- sales@jinghaopharma.com
- Country
- CHINA
- ProdList
- 153
- Advantage
- 58
- Tel
- 027-83850113 18171155316
- Fax
- 027-83855316
- 2821856175@qq.com
- Country
- China
- ProdList
- 4723
- Advantage
- 58
- Tel
- 21-33585366
- Fax
- +86-21-34979012
- export01@shyrchem.com
- Country
- CHINA
- ProdList
- 1319
- Advantage
- 58
- Tel
- 15850510341
- Fax
- 025-85722793
- shiqingran@wzxchem.com
- Country
- China
- ProdList
- 3746
- Advantage
- 58
- Tel
- +86-021-61551413 +8618813727289
- contact@trustwe.com
- Country
- China
- ProdList
- 5738
- Advantage
- 58
- Tel
- 0519-68985668 13685222090
- Fax
- qq735434464
- sales@kechem.cn
- Country
- China
- ProdList
- 26028
- Advantage
- 58
- Tel
- 28-85305008
- Country
- CHINA
- ProdList
- 964
- Advantage
- 58
- Tel
- 025-85560043 15850508050
- Fax
- 025-85563444
- info@synzest.com
- Country
- China
- ProdList
- 9286
- Advantage
- 58
- Tel
- 1701086315
- Fax
- 1701086315@qq.com
- dexuanpharma@126.com
- Country
- China
- ProdList
- 9475
- Advantage
- 58
- Tel
- 13675144456
- Fax
- 025-85563444
- sean.lv@synzest.com
- Country
- China
- ProdList
- 10784
- Advantage
- 58
- Tel
- 023-40768198 17725058315
- Fax
- 023-40768198
- 75235918@qq.com
- Country
- China
- ProdList
- 39
- Advantage
- 58
- Tel
- 021-51816796-820 13611835272
- Fax
- 021-5161 3951
- sales2@sunwaypharm.com
- Country
- China
- ProdList
- 44458
- Advantage
- 58
- Tel
- 021-021-61109150
- Fax
- 021-61105897
- sales@tcisct.com
- Country
- China
- ProdList
- 31121
- Advantage
- 58
- Tel
- 0371-0371-55153829 18003835034
- Fax
- 18003835034（微信）
- 2853979819@qq.com
- Country
- China
- ProdList
- 9734
- Advantage
- 58
- Tel
- 0757-85921206 18520245316
- 2329783215@qq.com
- Country
- China
- ProdList
- 12661
- Advantage
- 58
- Tel
- 027-59101668 19945030958
- Fax
- 027-59101668
- 2881924765@qq.com
- Country
- China
- ProdList
- 7890
- Advantage
- 58
- Tel
- 023-023-63134718 13983849334
- 1501533472@qq.com
- Country
- China
- ProdList
- 60
- Advantage
- 58
- Tel
- 400-6005915
- sales@picasso-e.com
- Country
- China
- ProdList
- 39653
- Advantage
- 58
- Tel
- +86-027-59232304 15387063101
- 2881924050@qq.com
- Country
- China
- ProdList
- 9959
- Advantage
- 58
- Tel
- 021-50706066 15221275939
- shenlinxing@macklin.cn
- Country
- China
- ProdList
- 29976
- Advantage
- 58
- Tel
- 18621169109
- market03@meryer.com
- Country
- China
- ProdList
- 27987
- Advantage
- 58
More
Less
View Lastest Price from N-Methyl-N-((3R,4R)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine dihydrochloride manufacturers
Hangzhou ICH Biofarm Co., Ltd
- Product
- N-Methyl-N-((3R,4R)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine dihydrochloride 1260590-51-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 0.1kg
- Purity
- 99.0%min
- Supply Ability
- 200kg
- Release date
- 2023-06-09
Career Henan Chemical Co
- Product
- N-Methyl-N-((3R,4R)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine dihydrochloride 1260590-51-9
- Price
- US $100.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2018-07-30
1260590-51-9, N-Methyl-N-((3R,4R)-4-Methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine dihydrochlorideRelated Search:
N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine dihydrochloride
N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
2-Isopropyl-4-[(N-methylamino)methyl]thiazole hydrochloride
Tofacitinib citrate
3-bis(4-Methylbenzoyloxy)succinate)
(3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride