ChemicalBook > CAS DataBase List > 1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylMethyl)-1,3-dioxolan-4-yl]Methoxy]phenyl]-4-(4-nitrophenyl)piperazine

1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylMethyl)-1,3-dioxolan-4-yl]Methoxy]phenyl]-4-(4-nitrophenyl)piperazine

Product Name
1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylMethyl)-1,3-dioxolan-4-yl]Methoxy]phenyl]-4-(4-nitrophenyl)piperazine
CAS No.
1437468-92-2
Chemical Name
1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylMethyl)-1,3-dioxolan-4-yl]Methoxy]phenyl]-4-(4-nitrophenyl)piperazine
Synonyms
Itraconazole Impurity 27;Itracozole?NitrophenylImpurity;Itraconazole Nitrophenyl Impurity;1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylMethyl)-1,3-dioxolan-4-yl]Methoxy]phenyl]-4-(4-nitrophenyl)piperazine;Piperazine, 1-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(4-nitrophenyl)-
CBNumber
CB42724616
Molecular Formula
C29H28Cl2N6O5
Formula Weight
611.48
MOL File
1437468-92-2.mol
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1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylMethyl)-1,3-dioxolan-4-yl]Methoxy]phenyl]-4-(4-nitrophenyl)piperazine Property

Melting point:
>88°C (dec.)
Boiling point:
816.2±75.0 °C(Predicted)
Density 
1.46±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly)
pka
5.97±0.40(Predicted)
form 
Solid
color 
Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D436390
Product name
1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(4-nitrophenyl)piperazine
Packaging
100mg
Price
$1455
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
64298
Product name
1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(4-nitrophenyl)piperazine
Packaging
10mg
Price
$650
Updated
2021/12/16
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1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylMethyl)-1,3-dioxolan-4-yl]Methoxy]phenyl]-4-(4-nitrophenyl)piperazine Chemical Properties,Usage,Production

Uses

1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(4-nitrophenyl)piperazine is an intermediate in the synthesis of derivatives of Itraconazole (I937500), an orally active antimycotic and antifungal compound.

1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylMethyl)-1,3-dioxolan-4-yl]Methoxy]phenyl]-4-(4-nitrophenyl)piperazine Preparation Products And Raw materials

Raw materials

Preparation Products

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1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylMethyl)-1,3-dioxolan-4-yl]Methoxy]phenyl]-4-(4-nitrophenyl)piperazine Suppliers

China 9 India 1 United States 1 Global 11
Chemsky（shanghai）International Co.,Ltd.
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021-50135380
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shchemsky@sina.com
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China
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Guangzhou Dreampharm Biotechnology Co., Ltd.
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020-36607679 17825480238
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QQ 3008233717
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3008233746@qq.com
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China
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Standardpharm Co. Ltd.
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86-714-3992388
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overseasales1@yongstandards.com
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United States
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14332
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58
Jinan blalong chemical co. LTD
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2710913286@.com
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1513643261@qq.com
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China
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14246
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Shenzhen Jianyi Biotechnology Co., Ltd
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0755-84826604
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3001783715@qq.com
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Energy Chemical
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021-58432009 400-005-6266
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Guangzhou Juntang Technology Co., Ltd
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sales@dmstandards.com
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China
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10945
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Scinova Biotech(Guangzhou) Co., Ltd.
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13268215580
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scinova_sales@163.com
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China
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7023
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Nantong Hanfang Biotechnology Co. , Ltd.
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18616537568
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hanfangpharma@126.com
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China
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29971
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1437468-92-2, 1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylMethyl)-1,3-dioxolan-4-yl]Methoxy]phenyl]-4-(4-nitrophenyl)piperazineRelated Search:

Propyl Itraconazole HYDROXY ITRACONAZOLE Itraconazole Des-(1-(sec-butyl)-1H-1,2,4-triazol-5(4H)-one) Itraconazole DPUDRFOQNBKHMF-YZNIXAGQSA-N cis-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-ylmethyl benzoate Itraconazole Impurity 34 2,4-Dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one 2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE N-Desalkyl Itraconazole trans-Itraconazole Butyl Itraconazole (1,2,4-Triazol-4-yl) Itraconazole cis-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-ylmethyl methanesulphonate KETO ITRACONAZOLE 1-(4-AMINOPHENYL)-4-(4-METHOXYPHENYL)PIPERAZINE Isopropyl Itraconazole cis-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-ylmethyl benzoate

  • 1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylMethyl)-1,3-dioxolan-4-yl]Methoxy]phenyl]-4-(4-nitrophenyl)piperazine
  • Itraconazole Nitrophenyl Impurity
  • Itraconazole Impurity 27
  • Itracozole?NitrophenylImpurity
  • Piperazine, 1-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(4-nitrophenyl)-
  • 1437468-92-2