CPI 360

Product Name: CPI 360
CAS No.: 1802175-06-9
Chemical Name: CPI 360
Synonyms: CPI360;CPI-360;CPI 360;CPI-360 (R);CPI360;CPI 360;1H-Indole-3-carboxamide, N-[(1,2-dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-
CBNumber: CB42729358
Molecular Formula: C25H31N3O4
Formula Weight: 437.53
MOL File: 1802175-06-9.mol

More

Less

CPI 360 Property

Boiling point:: 712.2±60.0 °C(Predicted)
Density: 1.26±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 10 mg/mL; DMSO: 25 mg/mL; Ethanol: 30 mg/mL; Ethanol:PBS (pH7.2) (1:7): 0.12 mg/mL
form: A crystalline solid
pka: 11.01±0.10(Predicted)
InChIKey: PFPSFENQCNMITC-MRXNPFEDSA-N
SMILES: N1([C@@H](C2CCOCC2)C)C2=C(C=CC=C2)C(C(NCC2=C(OC)C=C(C)NC2=O)=O)=C1C

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 19125
Product name: CPI-360
Purity: ≥98%
Packaging: 500μg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 19125
Product name: CPI-360
Purity: ≥98%
Packaging: 1mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 19125
Product name: CPI-360
Purity: ≥98%
Packaging: 5mg
Price: $231
Updated: 2024/03/01

Cayman Chemical

Product number: 19125
Product name: CPI-360
Purity: ≥98%
Packaging: 10mg
Price: $424
Updated: 2024/03/01

AK Scientific

Product number: 6715DW
Product name: CID73442743
Packaging: 10mg
Price: $569
Updated: 2021/12/16

More

Less

CPI 360 Chemical Properties,Usage,Production

Description

CPI-360 is a selective EZH2 inhibitor with IC₅₀ values of 0.5 and 2.5 nM for wild-type EZH2 and Y641N mutant EZH2, respectively. It decreases cellular levels of H3K27me3 and H3K27me2 (EC₅₀s = 56 and 65 nM, respectively), triggering cell cycle arrest and ultimately resulting in apoptosis in a large panel of non-Hodgkin’s lymphoma (NHL) cell lines. Twice daily, subcutaneous administration of 200 mg/kg of CPI-360 reduced tumor growth of KARPAS-422 xenografts in mice.

CPI 360 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

CPI 360 Suppliers

China 72 United States 9 Global 81

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38631
Advantage: 58

ApexBio Technology

Tel: --
Fax: --
Email: sales@apexbt.com
Country: United States
ProdList: 6251
Advantage: 58

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

More

Less

View Lastest Price from CPI 360 manufacturers

Hubei Chuchang Biotech Co., Ltd.

Product: CPI-360 1802175-06-9
Price: US $0.00-0.00/mg
Min. Order: 1mg
Purity: 98
Supply Ability: 100G
Release date: 2024-04-17

Career Henan Chemical Co

Product: CPI-360 1802175-06-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: Min98% HPLC
Supply Ability: g/kg/ton
Release date: 2020-01-01

1802175-06-9, CPI 360Related Search:

CPI 360

CPI360

CPI-360

CPI360;CPI 360

CPI-360 (R)

1H-Indole-3-carboxamide, N-[(1,2-dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-

1802175-06-9