ChemicalBook > CAS DataBase List > USP7-IN-1

USP7-IN-1

Product Name
USP7-IN-1
CAS No.
1381291-36-6
Chemical Name
USP7-IN-1
Synonyms
USP7i-1;USP7-IN-1;USP7 inhibitor 1;Inhibitor,inhibit,USP-7-IN-1,USP7IN1,USP7 IN 1,DUBs,Deubiquitinase;7-Chloro-3-((4-hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl)methyl)quinazolin-4(3H)-one;4(3H)-Quinazolinone, 7-chloro-3-[[4-hydroxy-1-(1-oxo-3-phenylpropyl)-4-piperidinyl]methyl]-
CBNumber
CB42729378
Molecular Formula
C23H24ClN3O3
Formula Weight
425.91
MOL File
1381291-36-6.mol
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USP7-IN-1 Property

Boiling point:
666.2±65.0 °C(Predicted)
Density 
1.32±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: ≥ 40 mg/mL (93.92 mM)
form 
Solid
pka
13.52±0.20(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-3515
Product name
USP7-IN-1
Purity
98.92%
Packaging
5mg
Price
$420
Updated
2021/12/16
ChemScene
Product number
CS-3515
Product name
USP7-IN-1
Purity
98.92%
Packaging
10mg
Price
$600
Updated
2021/12/16
ChemScene
Product number
CS-3515
Product name
USP7-IN-1
Purity
98.92%
Packaging
50mg
Price
$1800
Updated
2021/12/16
ChemScene
Product number
CS-3515
Product name
USP7-IN-1
Purity
98.92%
Packaging
100mg
Price
$2520
Updated
2021/12/16
Crysdot
Product number
CD31003679
Product name
USP7-IN-1
Purity
98+%
Packaging
5mg
Price
$243
Updated
2021/12/16
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USP7-IN-1 Chemical Properties,Usage,Production

Description

USP7-IN-1 is a selective and reversible inhibitor of ubiquitin-specific protease 7 (USP7), with an IC50 of 77 μM, and can be used for the research of cancer. IC50: 77 μM (USP7)[1]

USP7-IN-1 (Example 2) is a selective and reversible inhibitor of USP7, with an IC50 of 77 μM, and shows no inhibition of USP8, USP5, Uch-L1, Uch-L3 or caspase 3. USP7-IN-1 inhibits the proliferation of HCT116 cells, with a GI50 of 67 μM[1].

References

[1]. SELECTIVE AND REVERSIBLE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7. WO 2013030218 A1

USP7-IN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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USP7-IN-1 Suppliers

Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7887
Advantage
56
LETOPHARM LIMITED
Tel
+86-21-5821 5861
Fax
+86-21-5106 2861
Email
sales@letopharm.com
Country
China
ProdList
2384
Advantage
58
Birdo (Shanghai) Medical Technology Co., Ltd.
Tel
021-58099077
Fax
-
Email
sales@birdochem.com
Country
China
ProdList
185
Advantage
55
Shanghai Beckham Medical Technology Co., Ltd
Tel
021-13816613772 13816613772
Fax
QQ: 12922499
Email
huahero21@sina.com
Country
China
ProdList
558
Advantage
55
Guangzhou QiYun Biotechnology Co., Ltd.
Tel
020-61288194 61288195
Fax
020-61288700
Email
505721671@qq.com
Country
China
ProdList
3866
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4660
Advantage
60
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58

1381291-36-6, USP7-IN-1Related Search:


  • USP7-IN-1
  • 4(3H)-Quinazolinone, 7-chloro-3-[[4-hydroxy-1-(1-oxo-3-phenylpropyl)-4-piperidinyl]methyl]-
  • USP7i-1
  • USP7 inhibitor 1
  • Inhibitor,inhibit,USP-7-IN-1,USP7IN1,USP7 IN 1,DUBs,Deubiquitinase
  • 7-Chloro-3-((4-hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl)methyl)quinazolin-4(3H)-one
  • 1381291-36-6