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USP7-IN-1

Product Name
USP7-IN-1
CAS No.
1381291-36-6
Chemical Name
USP7-IN-1
Synonyms
USP7i-1;USP7-IN-1;USP7 inhibitor 1;Inhibitor,inhibit,USP-7-IN-1,USP7IN1,USP7 IN 1,DUBs,Deubiquitinase;7-Chloro-3-((4-hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl)methyl)quinazolin-4(3H)-one;4(3H)-Quinazolinone, 7-chloro-3-[[4-hydroxy-1-(1-oxo-3-phenylpropyl)-4-piperidinyl]methyl]-
CBNumber
CB42729378
Molecular Formula
C23H24ClN3O3
Formula Weight
425.91
MOL File
1381291-36-6.mol
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USP7-IN-1 Property

Boiling point:
666.2±65.0 °C(Predicted)
Density 
1.32±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: ≥ 40 mg/mL (93.92 mM)
form 
Solid
pka
13.52±0.20(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-3515
Product name
USP7-IN-1
Purity
98.92%
Packaging
5mg
Price
$420
Updated
2021/12/16
ChemScene
Product number
CS-3515
Product name
USP7-IN-1
Purity
98.92%
Packaging
10mg
Price
$600
Updated
2021/12/16
ChemScene
Product number
CS-3515
Product name
USP7-IN-1
Purity
98.92%
Packaging
50mg
Price
$1800
Updated
2021/12/16
ChemScene
Product number
CS-3515
Product name
USP7-IN-1
Purity
98.92%
Packaging
100mg
Price
$2520
Updated
2021/12/16
Crysdot
Product number
CD31003679
Product name
USP7-IN-1
Purity
98+%
Packaging
5mg
Price
$243
Updated
2021/12/16
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USP7-IN-1 Chemical Properties,Usage,Production

Description

USP7-IN-1 is a selective and reversible inhibitor of ubiquitin-specific protease 7 (USP7), with an IC50 of 77 μM, and can be used for the research of cancer. IC50: 77 μM (USP7)[1]

USP7-IN-1 (Example 2) is a selective and reversible inhibitor of USP7, with an IC50 of 77 μM, and shows no inhibition of USP8, USP5, Uch-L1, Uch-L3 or caspase 3. USP7-IN-1 inhibits the proliferation of HCT116 cells, with a GI50 of 67 μM[1].

References

[1]. SELECTIVE AND REVERSIBLE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7. WO 2013030218 A1

USP7-IN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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USP7-IN-1 Suppliers

China 28 United States 4 Global 32
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4660
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58

1381291-36-6, USP7-IN-1Related Search:


  • USP7-IN-1
  • 4(3H)-Quinazolinone, 7-chloro-3-[[4-hydroxy-1-(1-oxo-3-phenylpropyl)-4-piperidinyl]methyl]-
  • USP7i-1
  • USP7 inhibitor 1
  • Inhibitor,inhibit,USP-7-IN-1,USP7IN1,USP7 IN 1,DUBs,Deubiquitinase
  • 7-Chloro-3-((4-hydroxy-1-(3-phenylpropanoyl)piperidin-4-yl)methyl)quinazolin-4(3H)-one
  • 1381291-36-6