4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide

ChemicalBook > CAS DataBase List > 4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide

4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide

Product Name: 4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide
CAS No.: 420092-79-1
Chemical Name: 4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide
Synonyms: SW155246;SW155246 >=98% (HPLC);4-chloro-N-(4-hydroxynaphthalen- 1-yl)-3-nitrobenzenesulfonamide;4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide;Benzenesulfonamide, 4-chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-;SW 155246,cancer,hDNMT1,DNMTs,DNMT1 inhibitor,SW155246,Inhibitor,SW-155246,inhibit,mDNMT3A,DNA MTases,DNA Methyltransferase
CBNumber: CB42751098
Molecular Formula: C16H11ClN2O5S
Formula Weight: 378.79
MOL File: 420092-79-1.mol

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4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide Property

storage temp.: 2-8°C
solubility: DMSO: soluble10mg/mL, clear
form: powder
color: white to light brown

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Safety

Hazard Codes: Xi
Risk Statements: 36
Safety Statements: 26

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H319Causes serious eye irritation
Precautionary statements: P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1136
Product name: SW155246
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $105
Updated: 2022/05/15

Sigma-Aldrich

Product number: SML1136
Product name: SW155246
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $423
Updated: 2022/05/15

Cayman Chemical

Product number: 21865
Product name: SW155246
Purity: ≥98%
Packaging: 1mg
Price: $39
Updated: 2024/03/01

Cayman Chemical

Product number: 21865
Product name: SW155246
Purity: ≥98%
Packaging: 5mg
Price: $106
Updated: 2024/03/01

Cayman Chemical

Product number: 21865
Product name: SW155246
Purity: ≥98%
Packaging: 10mg
Price: $172
Updated: 2024/03/01

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4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide Chemical Properties,Usage,Production

Description

SW155246 is an inhibitor of DNA methyltransferase 1 (DNMT1; IC₅₀ = 1.2 μM). It is selective for human DNMT1 over murine DNMT3 (IC₅₀ = 38 μM). SW155246 inhibits HeLa and A549 tumor cell growth in a redox-independent manner (IC₅₀s = 8-20 μM). It also inhibits genomic methylation in HeLa cells when used at concentrations ranging from 10 to 18.6 μM.

4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide Suppliers

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420092-79-1, 4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamideRelated Search:

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4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide

SW155246

Benzenesulfonamide, 4-chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-

SW155246 >=98% (HPLC)

4-chloro-N-(4-hydroxynaphthalen- 1-yl)-3-nitrobenzenesulfonamide

SW 155246,cancer,hDNMT1,DNMTs,DNMT1 inhibitor,SW155246,Inhibitor,SW-155246,inhibit,mDNMT3A,DNA MTases,DNA Methyltransferase

420092-79-1