ChemicalBook > CAS DataBase List > (DEAMINO-CYS1,BETA-CYCLOHEXYL-ALA4,ARG8)-VASOPRESSIN
(DEAMINO-CYS1,BETA-CYCLOHEXYL-ALA4,ARG8)-VASOPRESSIN
- Product Name
- (DEAMINO-CYS1,BETA-CYCLOHEXYL-ALA4,ARG8)-VASOPRESSIN
- CAS No.
- 500170-27-4
- Chemical Name
- (DEAMINO-CYS1,BETA-CYCLOHEXYL-ALA4,ARG8)-VASOPRESSIN
- Synonyms
- d[Cha4]-AVP;(DeaMino-Cys1,Cha4,Arg8)-Vasopressin;(Deamino-Cys1,β-cyclohexyl-Ala4,Arg8)-Vasopressin;(Deamino-Cys1,β-cyclohexyl-Ala?,Arg?)-Vasopressin;(DeaMino-Cys1,b-cyclohexyl-Ala4,Arg8)-Vasopressin;(DEAMINO-CYS1,BETA-CYCLOHEXYL-ALA4,ARG8)-VASOPRESSIN;3-Mercaptopropionyl-Tyr-Phe-b-cyclohexyl-Ala-Asn-Cys-Pro-Arg-Gly-NH2;(Deamino-Cys1,b-cyclohexyl-Ala4,Arg8)-Vasopressin trifluoroacetate salt;3-MERCAPTOPROPIONYL-TYR-PHE-BETA-CYCLOHEXYL-ALA-ASN-CYS-PRO-ARG-GLY-NH2;(Deamino-Cys1,β-cyclohexyl-Ala?,Arg?)-Vasopressin trifluoroacetate salt
- CBNumber
- CB4279671
- Molecular Formula
- C50H71N13O11S2
- Formula Weight
- 1094.31
- MOL File
- 500170-27-4.mol
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(DEAMINO-CYS1,BETA-CYCLOHEXYL-ALA4,ARG8)-VASOPRESSIN Property
- storage temp.
- Store at RT
- form
- Solid
- color
- White to off-white
- Water Solubility
- Soluble to 1 mg/ml in Water
- Sequence
- {Mpa}-Tyr-Phe-{Cha}-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge:Mpa1-Cys6)
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N-Bromosuccinimide Price
Biosynth Carbosynth
- Product number
- FD109768
- Product name
- (Deamino-Cys1,b-cyclohexyl-Ala4,Arg8)-Vasopressin trifluoroacetate salt
- Packaging
- 500ug
- Price
- $115
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FD109768
- Product name
- (Deamino-Cys1,b-cyclohexyl-Ala4,Arg8)-Vasopressin trifluoroacetate salt
- Packaging
- 1mg
- Price
- $197
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FD109768
- Product name
- (Deamino-Cys1,b-cyclohexyl-Ala4,Arg8)-Vasopressin trifluoroacetate salt
- Packaging
- 2mg
- Price
- $343
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B5382
- Product name
- d[Cha4]-AVP
- Packaging
- 1mg
- Price
- $484
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FD109768
- Product name
- (Deamino-Cys1,b-cyclohexyl-Ala4,Arg8)-Vasopressin trifluoroacetate salt
- Packaging
- 5mg
- Price
- $685
- Updated
- 2021/12/16
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(DEAMINO-CYS1,BETA-CYCLOHEXYL-ALA4,ARG8)-VASOPRESSIN Chemical Properties,Usage,Production
Uses
d[Cha4]-AVP is a potent and selective vasopressin (AVP) V1b receptor agonist with a Ki of 1.2 nM for human V1b receptor. d[Cha4]-AVP shows more selective for V1b receptor than human V1a receptor, V2 receptor, and oxytocin receptors[1][2].
References
[1] Ling Ling Cheng, et al. Design of potent and selective agonists for the human vasopressin V1b receptor based on modifications of [deamino-cys1]arginine vasopressin at position 4. J Med Chem. 2004 Apr 22;47(9):2375-88. DOI:10.1021/jm030611c
[2] Cristiana Griffante, et al. Selectivity of d[Cha4]AVP and SSR149415 at human vasopressin and oxytocin receptors: evidence that SSR149415 is a mixed vasopressin V1b/oxytocin receptor antagonist. Br J Pharmacol. 2005 Nov;146(5):744-51. DOI:10.1038/sj.bjp.0706383
(DEAMINO-CYS1,BETA-CYCLOHEXYL-ALA4,ARG8)-VASOPRESSIN Preparation Products And Raw materials
Raw materials
Preparation Products
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500170-27-4, (DEAMINO-CYS1,BETA-CYCLOHEXYL-ALA4,ARG8)-VASOPRESSINRelated Search:
LCAT
3-MERCAPTOPROPIONYL-BETA-3-PYRIDYL-D-ALA-PHE-GLN-ASN-CYS-PRO-ARG-GLY-NH2
3-MERCAPTO-3-METHYL-BUTYRYL-TYR(ME)-PHE-GLN-ASN-CYS-PRO-ARG-GLY-NH2
3-MERCAPTOPROPIONYL-TYR-PHE-GLN-ASN-CYS-PRO-LYS-GLY-NH2, (DISULFIDE BOND)
D[LEU4,LYS8]-VP
3-MERCAPTO-3-METHYL-BUTYRYL-TYR-PHE-VAL-ASN-CYS-PRO-D-ARG-GLY-NH2
Desmopressin
(DEAMINO-CYS1,D-ORN8)-VASOPRESSIN
(DEAMINO-CYS1,VAL4,D-ARG8)-VASOPRESSIN
(DEAMINO-CYS1,BETA-CYCLOHEXYL-ALA4,ARG8)-VASOPRESSIN