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Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate

Product Name
Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate
CAS No.
82692-93-1
Chemical Name
Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate
Synonyms
TOOS;Trinder Reagent;TOOS, SODIUM SALT;TOOS extrapure, 98%;N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-3-METHYLANILINE;N-ETHYL-N-SULFOHYDROXYPROPYL-M-TOLUIDINE SODIUM SALT;Peroxidase/Hydrogen Peroxide Detection , Colorimetry;N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-*M-T OLUIDINE SO;N-ETHYL-N-SULPHOHYDROXYPROPYL-M-TOLUIDINE, SODIUM SALT;SODIUM N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-M-TOLUIDINE
CBNumber
CB4279813
Molecular Formula
C12H20NNaO4S
Formula Weight
297.34
MOL File
82692-93-1.mol
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Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate Property

storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
Solid
color 
White to Almost white
BRN 
5689521
InChI
InChI=1S/C12H19NO4S.Na.H/c1-3-13(8-12(14)9-18(15,16)17)11-6-4-5-10(2)7-11;;/h4-7,12,14H,3,8-9H2,1-2H3,(H,15,16,17);;
InChIKey
IRQRBVOQGUPTLG-UHFFFAOYSA-M
SMILES
N(C1C=CC=C(C)C=1)(CC)CC(O)CS(O)(=O)=O.[NaH]
CAS DataBase Reference
82692-93-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
3
HS Code 
29214200
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E8631
Product name
3-(N-Ethyl-3-methylanilino)-2-hydroxypropanesulfonic acid sodium salt
Purity
for enzymic, spectrophotometric det. of H
Packaging
1g
Price
$246
Updated
2025/07/31
Sigma-Aldrich
Product number
04340
Product name
3-(N-Ethyl-3-methylanilino)-2-hydroxypropanesulfonic acid sodium salt
Purity
for enzymic, spectrophotometric determination of H
Packaging
500mg
Price
$105
Updated
2025/07/31
TCI Chemical
Product number
S0805
Product name
Sodium 3-[Ethyl(m-tolyl)amino]-2-hydroxy-1-propanesulfonate Hydrate
Purity
>98.0%(HPLC)
Packaging
1g
Price
$33
Updated
2025/07/31
TCI Chemical
Product number
S0805
Product name
Sodium 3-[Ethyl(m-tolyl)amino]-2-hydroxy-1-propanesulfonate Hydrate
Purity
>98.0%(HPLC)
Packaging
5g
Price
$94
Updated
2025/07/31
Sigma-Aldrich
Product number
E8631
Product name
3-(N-Ethyl-3-methylanilino)-2-hydroxypropanesulfonic acid sodium salt
Purity
for enzymic, spectrophotometric det. of H
Packaging
5g
Price
$912
Updated
2025/07/31
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Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate Chemical Properties,Usage,Production

Description

Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate is a water-soluble reagent used in the enzymatic photometric determination of hydrogen peroxide. This compound is a widely studied small molecule inhibitor in scientific research. Originally synthesized in the early 1980s, it has since found extensive use in various investigations into cellular processes. It has its inhibition of the Na+/H+ exchanger (NHE), which is a membrane protein crucial for regulating intracellular pH. Additionally, EIPA has shown its potential as an inhibitor of TRPV channels, which play a role in pain sensation and thermoregulation. Another significant finding indicates Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate′s inhibition of the Na+/Ca2+ exchanger (NCX), responsible for regulating intracellular calcium levels.

Chemical Properties

White crystalline powder

Uses

TOOS (TOOS sodium salt) is a highly water-soluble aniline derivative widely used in diagnostics and biological experiments. TOOS can be combined with 3-methyl-2-benzothiazolinone hydrazone hydrochloride (MBTH) to form a chromogenic system to measure oxidase activity. In the MBTH-TOOS chromogenic system, MBTH is catalytically oxidized to produce (-NH) free radicals, which react with TOOS to form colorless compounds. Furthermore, the colorless compound undergoes a disproportionation reaction to produce a blue-violet quinoid compound[1].

References

[1] Lin X, et al. Boosting the oxidase-like activity of platinum nanozyme in MBTH-TOOS chromogenic system for detection of trypsin and its inhibitor. Talanta. 2021 Nov 1;234:122647. DOI:10.1016/j.talanta.2021.122647

Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate Preparation Products And Raw materials

Raw materials

Preparation Products

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Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate Suppliers

Novachemistry
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United Kingdom
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View Lastest Price from Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate 82692-93-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
3500kg/month
Release date
2025-09-02
Wuhan Fortuna Chemical Co.,Ltd
Product
Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate 82692-93-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
2000KG
Release date
2025-08-30
Hebei Chuanghai Biotechnology Co., Ltd
Product
Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate 82692-93-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-30

82692-93-1, Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonateRelated Search:


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  • 82692-93-1
  • C12H18NaO4S
  • C12H18NNaO4SxH2O
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