ChemicalBook > CAS DataBase List > MASTOPARAN

MASTOPARAN

Product Name
MASTOPARAN
CAS No.
72093-21-1
Chemical Name
MASTOPARAN
Synonyms
MASTOPARAN;NSC 351907;Mastoparan-1;INLKALAALAKKIL;INLKALAALAKKIL-NH2;Mastoparan(acetate);MASTOPARAN USP/EP/BP;MASTOPARAN 4ACOH 6H2O;MASTOPARAN VESPULA LEWISII;Mastoparan from Vespula lewisii
CBNumber
CB4292335
Molecular Formula
C70H131N19O15
Formula Weight
1478.91
MOL File
72093-21-1.mol
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MASTOPARAN Property

Boiling point:
1676.8±65.0 °C(Predicted)
Density 
1.150±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
H2O: 1 mg/mL, clear, colorless
form 
White solid
pka
13.43±0.46(Predicted)
color 
white
BRN 
5491949
Sequence
H-Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
10
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H317May cause an allergic skin reaction

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P285In case of inadequate ventilation wear respiratory protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P321Specific treatment (see … on this label).

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M5280
Product name
Mastoparan, Vespula lewisii
Purity
≥97% (HPLC), powder
Packaging
1mg
Price
$98.4
Updated
2024/03/01
Sigma-Aldrich
Product number
444898
Product name
Mastoparan
Purity
A cell-permeable synthetic peptide with sequence identical to
Packaging
1mg
Price
$230
Updated
2024/03/01
Cayman Chemical
Product number
20240
Product name
Mastoparan
Purity
≥95%
Packaging
500μg
Price
$55
Updated
2021/12/16
Cayman Chemical
Product number
20240
Product name
Mastoparan
Purity
≥95%
Packaging
1mg
Price
$88
Updated
2021/12/16
Sigma-Aldrich
Product number
M5280
Product name
Mastoparan, Vespula lewisii
Purity
≥97% (HPLC), powder
Packaging
5mg
Price
$660
Updated
2024/03/01
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MASTOPARAN Chemical Properties,Usage,Production

Uses

Mastoparan has been used as a calmodulin antagonist.

Definition

ChEBI: A member of the class of mastopyrans that is a 14-amino acid polypeptide comprising isoleucyl, asparaginyl, leucyl, lysyl, alanyl, leucyl, alanyl, alanyl, leucyl, alanyl, lysyl, lysyl, isoleucyl, and leucinamide residues coupled in sequence. It is the majo active component of the venom of the vespid wasp, Vespula lewisii and causes degranulation of mast cells.

General Description

Mastoparan is a cationic, amphiphilic, tetradecapeptide amide. It is composed of the restricted amino acid and the repeated sequence. This protein is a nonspecific secretagogue isolated from venom of wasp.

Biochem/physiol Actions

Mastoparan effectively stimulates exocytosis from diverse mammalian cells. The encoded protein facilitates the secretion of histamine from mast cells, serotonin from platelets, catecholamines from chromaffin cells and prolactin from the anterior pituitary. In addition, it is also involved in activation of Phospholipase A2 and phosphoinositides (Pl) break down. Mastoparan functions as an inhibitor for calmodulin-stimulated phosphodiesterase. Mastoparan helps in mitochondrial permeability transition by enhancing an apparent bimodal mechanism of action.

MASTOPARAN Preparation Products And Raw materials

Raw materials

Preparation Products

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72093-21-1, MASTOPARANRelated Search:


  • MASTOPARAN
  • MASTOPARAN 4ACOH 6H2O
  • MASTOPARAN VESPULA LEWISII
  • INLKALAALAKKIL
  • INLKALAALAKKIL-NH2
  • H-ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-LYS-ILE-LEU-NH2
  • ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-LYS-ILE-LEU-NH2
  • ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-LYS-ILE-LEU-NH2 4ACOH 6H2O
  • Mastcelldegranulatingpeptide(Vespulalewisii)
  • Mastoparan from Vespula lewisii
  • MASTOPARAN TRIFLUOROACETATE SALT >99% PE PTIDE FROM WASP VEN
  • L-Ile-L-Asn-L-Leu-L-Lys-L-Ala-L-Leu-L-Ala-L-Ala-L-Leu-L-Ala-L-Lys-L-Lys-L-Ile-L-Leu-NH2
  • MASTOPARAN USP/EP/BP
  • Mastoparan-1
  • NSC 351907
  • Mastoparan(acetate)
  • 72093-21-1
  • C70H131N19O15
  • C70H129N19O15
  • Other Peptides
  • Peptides
  • BioChemical
  • Biochemicals and Reagents
  • Amino Acids and Peptides
  • Peptide
  • Phospholipase ActivatorsCell Signaling and Neuroscience
  • Phospholipid Metabolism
  • Lipids in Cell Signaling
  • Toxins and Venoms
  • Wasp
  • G-Protein