MASTOPARAN
- Product Name
- MASTOPARAN
- CAS No.
- 72093-21-1
- Chemical Name
- MASTOPARAN
- Synonyms
- MASTOPARAN;NSC 351907;Mastoparan-1;INLKALAALAKKIL;INLKALAALAKKIL-NH2;Mastoparan(acetate);MASTOPARAN USP/EP/BP;MASTOPARAN 4ACOH 6H2O;MASTOPARAN VESPULA LEWISII;Mastoparan from Vespula lewisii
- CBNumber
- CB4292335
- Molecular Formula
- C70H131N19O15
- Formula Weight
- 1478.91
- MOL File
- 72093-21-1.mol
MASTOPARAN Property
- Boiling point:
- 1676.8±65.0 °C(Predicted)
- Density
- 1.150±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- H2O: 1 mg/mL, clear, colorless
- form
- White solid
- pka
- 13.43±0.46(Predicted)
- color
- white
- BRN
- 5491949
- Sequence
- H-Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P285In case of inadequate ventilation wear respiratory protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P321Specific treatment (see … on this label).
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- M5280
- Product name
- Mastoparan, Vespula lewisii
- Purity
- ≥97% (HPLC), powder
- Packaging
- 1mg
- Price
- $98.4
- Updated
- 2024/03/01
- Product number
- 444898
- Product name
- Mastoparan
- Purity
- A cell-permeable synthetic peptide with sequence identical to
- Packaging
- 1mg
- Price
- $230
- Updated
- 2024/03/01
- Product number
- 20240
- Product name
- Mastoparan
- Purity
- ≥95%
- Packaging
- 500μg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- 20240
- Product name
- Mastoparan
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $88
- Updated
- 2021/12/16
- Product number
- M5280
- Product name
- Mastoparan, Vespula lewisii
- Purity
- ≥97% (HPLC), powder
- Packaging
- 5mg
- Price
- $660
- Updated
- 2024/03/01
MASTOPARAN Chemical Properties,Usage,Production
Uses
Mastoparan has been used as a calmodulin antagonist.
Definition
ChEBI: A member of the class of mastopyrans that is a 14-amino acid polypeptide comprising isoleucyl, asparaginyl, leucyl, lysyl, alanyl, leucyl, alanyl, alanyl, leucyl, alanyl, lysyl, lysyl, isoleucyl, and leucinamide residues coupled in sequence. It is the majo active component of the venom of the vespid wasp, Vespula lewisii and causes degranulation of mast cells.
General Description
Mastoparan is a cationic, amphiphilic, tetradecapeptide amide. It is composed of the restricted amino acid and the repeated sequence. This protein is a nonspecific secretagogue isolated from venom of wasp.
Biochem/physiol Actions
Mastoparan effectively stimulates exocytosis from diverse mammalian cells. The encoded protein facilitates the secretion of histamine from mast cells, serotonin from platelets, catecholamines from chromaffin cells and prolactin from the anterior pituitary. In addition, it is also involved in activation of Phospholipase A2 and phosphoinositides (Pl) break down. Mastoparan functions as an inhibitor for calmodulin-stimulated phosphodiesterase. Mastoparan helps in mitochondrial permeability transition by enhancing an apparent bimodal mechanism of action.