Ethyl methanesulfonate

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Ethyl methanesulfonate

Product Name: Ethyl methanesulfonate
CAS No.: 62-50-0
Chemical Name: Ethyl methanesulfonate
Synonyms: EMS;ETHYL MESYLATE;METHANESULFONIC ACID ETHYL ESTER;CB 1528;Ethyl methansulfonate;ETHYL METHANESULPHONATE;ethylesterofmethylsulfonicacid;ethylesterofmethanesulfonicacid;ethylesterofmethylsulphonicacid;ethylesterofmethanesulphonicacid
CBNumber: CB4292779
Molecular Formula: C3H8O3S
Formula Weight: 124.16
MOL File: 62-50-0.mol

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Ethyl methanesulfonate Property

Melting point:: <25 °C
Boiling point:: 85-86 °C/10 mmHg (lit.)
Density: 1.206 g/mL at 20 °C
vapor pressure: 0.27 hPa (25 °C)
refractive index: n20/D 1.418(lit.)
Flash point:: 100 °C
storage temp.: 2-8°C
solubility: 50-100g/l
form: liquid
color: Colourless to Pale Yellow
Water Solubility: Miscible with water.
Sensitive: Moisture Sensitive
Merck: 14,3827
BRN: 773969
Stability:: Stable. Combustible. Incompatible with water, alkalies, oxidizing agents.
InChIKey: PLUBXMRUUVWRLT-UHFFFAOYSA-N
CAS DataBase Reference: 62-50-0(CAS DataBase Reference)
NIST Chemistry Reference: Methanesulfonic acid, ethyl ester(62-50-0)
IARC: 2B (Vol. 7, Sup 7) 1987
EPA Substance Registry System: Ethyl methanesulfonate (62-50-0)

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Safety

Hazard Codes: T
Risk Statements: 46-22-40-36/37/38-45
Safety Statements: 53-23-36/37/39-45-36/37-37/39-26
RIDADR: 2810
WGK Germany: 3
RTECS: PB2100000
F: 10-21
TSCA: Yes
HazardClass: 6.1
PackingGroup: II
HS Code: 29041000
Hazardous Substances Data: 62-50-0(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H340May cause genetic defects

H350May cause cancer

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M0880
Product name: Ethyl methanesulfonate
Purity: liquid
Packaging: 1g
Price: $43.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.20774
Product name: Ethyl methanesulfonate
Purity: for synthesis
Packaging: 5ml
Price: $47
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.20774
Product name: Ethyl methanesulfonate
Purity: for synthesis
Packaging: 25mL
Price: $153
Updated: 2024/03/01

Sigma-Aldrich

Product number: 72945
Product name: Ethyl methanesulfonate
Purity: certified reference material, TraceCERT
Packaging: 120mg
Price: $131
Updated: 2024/03/01

TCI Chemical

Product number: M0607
Product name: Ethyl Methanesulfonate
Purity: >99.0%(GC)
Packaging: 25g
Price: $51
Updated: 2024/03/01

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Ethyl methanesulfonate Chemical Properties,Usage,Production

Chemical Properties

colourless liquid

Chemical Properties

Ethyl methane sulfonate is a clear liquid.

Uses

Ethyl methanesulfonate is used as mutagen for both mammalian and plant cells. It finds application as a model alkylating agent in the study of deoxyribonucleic acid (DNA) repair processes.

Uses

Experimentally as mutagen, teratogen and brain carcinogen.

Definition

ChEBI: A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with ethanol.

General Description

Clear colorless liquid. Denser than water.

Air & Water Reactions

Water soluble.

Reactivity Profile

Ethyl methanesulfonate alkylates nucleophiles such as hydroxy, amino and sulfhydryl groups in model and biological materials. Is hydrolyzed by excess aqueous alkali to non-corrosive and non-toxic products. Is hydrolyzed by water to a highly corrosive product .

Fire Hazard

Ethyl methanesulfonate is combustible.

Biochem/physiol Actions

Ethyl methanesulfonate is a DNA ethylating agent, mutagenic to plants and animals and carcinogenic in mammals. It has been used as a model alkylating agent in studies of DNA repair processes. EMS induces base substitutions of guanine-cytosine (G/C) to adenine-thymine (A/T). EMS also generates point mutations and single nucleotide polymorphisms in genomes. EMS is potential chemical mutagen used for inducing mutation in rice, wheat and Arabidopsis thaliana.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, neoplas tigenic, tumorigenic, and teratogenic data. Poison by ingestion and intraperitoneal routes. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of SOx. See also SULFONATES and ESTERS.

Potential Exposure

Used as a research tool for mutagenesis and carcinogenesis studies. Was considered as a possible human male contraceptive. Also considered as a reversible male hemosterilant for insects and mammalian pests.

Carcinogenicity

Ethyl methanesulfonate is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

Shipping

UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. Military driver shall be given full and complete information regarding shipment and conditions in case of emergency. AR 50-6 deals specifically with the shipment of chemical agents. Shipments of agent will be escorted in accordance with AR 740-32.

Incompatibilities

Vapors may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, and epoxides. Contact with moisture may cause hydrolysis or other forms of decomposition

Ethyl methanesulfonate Preparation Products And Raw materials

Raw materials

Methanesulfonyl chloride

Preparation Products

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View Lastest Price from Ethyl methanesulfonate manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Ethyl methanesulfonate 62-50-0
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000
Release date: 2024-05-09

Hebei Weibang Biotechnology Co., Ltd

Product: Ethyl methanesulfonate 62-50-0
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-10-25

Hebei Chuanghai Biotechnology Co,.LTD

Product: Ethyl Methanesulfonate 62-50-0
Price: US $10.50/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 ton
Release date: 2024-08-08

62-50-0, Ethyl methanesulfonateRelated Search:

Methyl methanesulfonate ISOPROPYL METHANESULFONATE N-Methyl methanesulfonamide ETHYL METHANESULFONYLACETATE (-)-1,4-DI-O-TOSYL-2,3-O-ISOPROPYLIDENETHREITOL Bromoxylenol Blue Ethyl trifluoromethanesulfonate 1,3-Propane sultone Tetrabromophenol Blue Thymol Blue Bromocresol green P-XYLENOL BLUE 3-CHLORO-3H-2,1-BENZOXATHIOLE-1,1-DIOXIDE Phenol Red Pyrocatechol Violet BTB Cresol Purple PYROGALLOL RED Ethyl Mesylate

CB 1528

EMS

ENT 26396

ent26396

Ethyl ester of methanesulfonic acid

Ethyl ester of methanesulphonic acid

Ethyl ester of methylsulfonic acid

Ethyl ester of methylsulphonic acid

Ethyl methansulfonate

Ethyl methansulphonate

Ethylester kyseliny methansulfonove

ethylesterkyselinymethansulfonove

ethylesterofmethanesulfonicacid

ethylesterofmethanesulphonicacid

ethylesterofmethylsulfonicacid

ethylesterofmethylsulphonicacid

ethylmethansulfonate

ethylmethansulphonate

Ethylmethylsulfonate

Half-Myleran

Methanesulphonic acid ethyl ester

methanesulphonicacid,ethylester

methanesulphonicacidethylester

Methylsulfonic acid, ethyl ester

methylsulfonicacid,ethylester

methylsulfonicacidethylester

NSC 26805

nsc26805

Rcra waste number U119

rcrawastenumberu119

ETHYL MESYLATE

ETHYL METHANESULFONATE

ETHYL METHANESULPHONATE

METHANESULFONIC ACID ETHYL ESTER

Imatinib Impurity Ethyl Methane Sulfonate

Ethylmesilate

O-Ethyl methylsulfonate

Methanesulfonic acid ethyl

EthylmethaneSulphonate99%

Ethylmethanesulfonate,99%

ETHYLMETHANOSULPHONATE

ETHYLENEMETHANESULFONATE

ETHYLMETHYLSULPHONATE

Methanesulfonic acid, ethyl ester: (Ethyl methanesulfonate)

ETHYL METHANESULPHONATE extrapure

Ethyl mesylate, Methanesulfonic acid ethyl ester

Ethyl methanesulfonate,Ethyl mesylate, Methanesulfonic acid ethyl ester

Ethyl methanesulfonate 100mg [62-50-0]

Ethyl methanesulfonate ,98.5%

Ethyl Methane sulfonic acid

Ethylmethane Sulphonate 99%

Ethyl Methanesulfonate, 99% 10GR

Ethyl Methanesulfonate, 99% 25GR

Ethylmethanesu

Ethyl methanesulfonate (EMS)

ethylemethanesulfonate

Ethyl methanesulfonate reference

EthylMethanesulfonate&gt