4-CHLORO-3-FLUOROPHENYLACETIC ACID
- Product Name
- 4-CHLORO-3-FLUOROPHENYLACETIC ACID
- CAS No.
- 883500-51-4
- Chemical Name
- 4-CHLORO-3-FLUOROPHENYLACETIC ACID
- Synonyms
- Acid 3-fluoro-4-chloro;4-Chloro-3-fluorphenylaceticacid;3-fluoro-4-chlorophenylacetic acid;4-CHLORO-3-FLUOROPHENYLACETIC ACID;4-Chloro-3-fluorobenzeneacetic acid;2-(4-Chloro-3-fluorophenyl)acec Acid;4-Chloro-3-fluorophenylaceticacid,97%;Benzeneacetic acid, 4-chloro-3-fluoro-
- CBNumber
- CB4293004
- Molecular Formula
- C8H6ClFO2
- Formula Weight
- 188.58
- MOL File
- Mol file
4-CHLORO-3-FLUOROPHENYLACETIC ACID Property
- Melting point:
- 88-91℃
- Boiling point:
- 293.1±25.0 °C(Predicted)
- Density
- 1.417±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 3.97±0.10(Predicted)
- Appearance
- White to off-white Solid
Safety
- Hazard Codes
- Xi,E
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- Hazard Note
- Irritant
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- C584713
- Product name
- 4-Chloro-3-fluorophenylaceticacid
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- C584713
- Product name
- 4-Chloro-3-fluorophenylaceticacid
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FC63966
- Product name
- 4-Chloro-3-fluorophenylacetic acid
- Packaging
- 5G
- Price
- $50
- Updated
- 2021/12/16
- Product number
- 009488
- Product name
- 4-Chloro-3-fluorophenylacetic acid
- Purity
- 98%
- Packaging
- 5g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- PC9429
- Product name
- 4-Chloro-3-fluorophenylaceticacid
- Packaging
- 5g
- Price
- $50
- Updated
- 2021/12/16
4-CHLORO-3-FLUOROPHENYLACETIC ACID Chemical Properties,Usage,Production
Synthesis
251570-03-3
883500-51-4
General procedure for the synthesis of 4-chloro-3-fluorophenylacetic acid from 3-fluoro-4-chlorophenylacetonitrile: A mixture of 3-fluoro-4-chlorophenylacetonitrile (7.8 g, 0.046 mol), water (7.5 mL), concentrated sulfuric acid (7.5 mL) and acetic acid (7.5 mL) was heated and refluxed for 2 hours. After the reaction was completed, the mixture was cooled to room temperature and then slowly poured into ice water. The precipitated solid product was collected by filtration and washed with ether to yield 4-chloro-3-fluorophenylacetic acid (6.8 g, 79% yield). The structure of the product was confirmed by 1H NMR (300 MHz, DMSO-d6): δ 3.64 (s, 2H), 7.14 (ddd, J = 0.6, 2.1, 8.2 Hz, 1H), 7.34 (dd, J = 2.1, 10.6 Hz, 1H), 7.52 (t, J = 8.1 Hz, 1H). Mass spectrum (ESI-) m/z: 187 [M-H]-.
References
[1] Patent: WO2010/31, 2010, A1. Location in patent: Page/Page column 55
[2] Patent: WO2010/32, 2010, A1. Location in patent: Page/Page column 54
[3] Patent: WO2010/30, 2010, A1. Location in patent: Page/Page column 48
4-CHLORO-3-FLUOROPHENYLACETIC ACID Preparation Products And Raw materials
Raw materials
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View Lastest Price from 4-CHLORO-3-FLUOROPHENYLACETIC ACID manufacturers
- Product
- 4-CHLORO-3-FLUOROPHENYLACETIC ACID 883500-51-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-26