1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE
- Product Name
- 1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE
- CAS No.
- 68104-62-1
- Chemical Name
- 1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE
- Synonyms
- RARECHEM AH CK 0050;1-(4-Bromophenyl)piperazin HCl;1-(4-BROMOPHENYL)-PIPERAZINE HCL;1-(4-Bromophenyl)-piperazine x HCl;1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE;1-(4-Bromophenyl)piperazineHydrochloride>1-(4-Bromophenyl)piperazine hydrochloride 98%;1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE ISO 9001:2015 REACH
- CBNumber
- CB4301491
- Molecular Formula
- C10H14BrClN2
- Formula Weight
- 277.59
- MOL File
- 68104-62-1.mol
1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE Property
- Melting point:
- >280°C (dec.)
- storage temp.
- Inert atmosphere,Room Temperature
- Water Solubility
- Soluble in water
- solubility
- DMSO: 10 mg/ml; PBS (pH 7.2): 10 mg/ml
- form
- powder to crystal
- color
- White to Almost white
- InChI
- InChI=1S/C10H13BrN2.ClH/c11-9-1-3-10(4-2-9)13-7-5-12-6-8-13;/h1-4,12H,5-8H2;1H
- InChIKey
- YDVSFRZKQMQPJD-UHFFFAOYSA-N
- SMILES
- C1(C=CC(Br)=CC=1)N1CCNCC1.Cl
- CAS DataBase Reference
- 68104-62-1(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- Hazard Note
- Irritant
- HS Code
- 2933.59.8000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- B3630
- Product name
- 1-(4-Bromophenyl)piperazine Hydrochloride
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 1g
- Price
- $86
- Updated
- 2025/07/31
- Product number
- B3630
- Product name
- 1-(4-Bromophenyl)piperazine Hydrochloride
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 5g
- Price
- $288
- Updated
- 2025/07/31
- Product number
- 30229
- Product name
- 1-(4-Bromophenyl)piperazine (hydrochloride)
- Packaging
- 1mg
- Price
- $44
- Updated
- 2024/03/01
- Product number
- 30229
- Product name
- 1-(4-Bromophenyl)piperazine (hydrochloride)
- Packaging
- 5mg
- Price
- $109
- Updated
- 2024/03/01
- Product number
- B700288
- Product name
- 1-(4-Bromophenyl)piperazine Hydrochloride
- Packaging
- 1g
- Price
- $40
- Updated
- 2021/12/16
1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE Chemical Properties,Usage,Production
Description
1-(4-Bromophenyl)piperazine hydrochloride is an important organic synthetic intermediate, playing a crucial role, especially in medicinal chemistry. It is not typically used as a final product, but rather introduced as a structural unit (i.e., a "building block") into more complex molecules to construct drug molecules with specific biological activities. The "p-bromophenyl" and "piperazine ring" contained in its structure are common pharmacophores in many central nervous system drugs, such as antipsychotics and antidepressants.
Uses
1-(4-Bromophenyl)piperazine Hydrochloride is useful in the synthesis of large bifunctional heterocycles use in targeted degradation of rapidly accelerated fibrosarcoma polypeptides
Synthesis
P-Bromoaniline undergoes a biphilic nucleophilic substitution reaction with bis(2-chloroethyl)amine in the presence of a base (e.g., sodium carbonate) to directly generate 1-(4-bromophenyl)piperazine. Finally, 1-(4-bromophenyl)piperazine reacts with hydrochloric acid to synthesize 1-(4-bromophenyl)piperazine hydrochloride.
1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE manufacturers
- Product
- 1-(4-Bromophenyl)piperazine hydrochloride 68104-62-1
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1KG
- Purity
- 99.0%+
- Supply Ability
- 800 tons
- Release date
- 2020-04-29
- Product
- 1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE 68104-62-1
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-24