ChemicalBook > CAS DataBase List > 1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE

1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE

Product Name
1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE
CAS No.
68104-62-1
Chemical Name
1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE
Synonyms
RARECHEM AH CK 0050;1-(4-Bromophenyl)piperazin HCl;1-(4-BROMOPHENYL)-PIPERAZINE HCL;1-(4-Bromophenyl)-piperazine x HCl;1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE;1-(4-Bromophenyl)piperazineHydrochloride>1-(4-Bromophenyl)piperazine hydrochloride 98%;1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE ISO 9001：2015 REACH
CBNumber
CB4301491
Molecular Formula
C10H14BrClN2
Formula Weight
277.59
MOL File
68104-62-1.mol
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1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE Property

Melting point:
>280°C (dec.)
storage temp. 
Inert atmosphere,Room Temperature
Water Solubility 
Soluble in water
solubility 
DMSO: 10 mg/ml; PBS (pH 7.2): 10 mg/ml
form 
powder to crystal
color 
White to Almost white
InChI
InChI=1S/C10H13BrN2.ClH/c11-9-1-3-10(4-2-9)13-7-5-12-6-8-13;/h1-4,12H,5-8H2;1H
InChIKey
YDVSFRZKQMQPJD-UHFFFAOYSA-N
SMILES
C1(C=CC(Br)=CC=1)N1CCNCC1.Cl
CAS DataBase Reference
68104-62-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
Hazard Note 
Irritant
HS Code 
2933.59.8000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
B3630
Product name
1-(4-Bromophenyl)piperazine Hydrochloride
Purity
>98.0%(HPLC)(N)
Packaging
1g
Price
$86
Updated
2025/07/31
TCI Chemical
Product number
B3630
Product name
1-(4-Bromophenyl)piperazine Hydrochloride
Purity
>98.0%(HPLC)(N)
Packaging
5g
Price
$288
Updated
2025/07/31
Cayman Chemical
Product number
30229
Product name
1-(4-Bromophenyl)piperazine (hydrochloride)
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
30229
Product name
1-(4-Bromophenyl)piperazine (hydrochloride)
Packaging
5mg
Price
$109
Updated
2024/03/01
TRC
Product number
B700288
Product name
1-(4-Bromophenyl)piperazine Hydrochloride
Packaging
1g
Price
$40
Updated
2021/12/16
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1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE Chemical Properties,Usage,Production

Description

1-(4-Bromophenyl)piperazine hydrochloride is an important organic synthetic intermediate, playing a crucial role, especially in medicinal chemistry. It is not typically used as a final product, but rather introduced as a structural unit (i.e., a "building block") into more complex molecules to construct drug molecules with specific biological activities. The "p-bromophenyl" and "piperazine ring" contained in its structure are common pharmacophores in many central nervous system drugs, such as antipsychotics and antidepressants.

Uses

1-(4-Bromophenyl)piperazine Hydrochloride is useful in the synthesis of large bifunctional heterocycles use in targeted degradation of rapidly accelerated fibrosarcoma polypeptides

Synthesis

P-Bromoaniline undergoes a biphilic nucleophilic substitution reaction with bis(2-chloroethyl)amine in the presence of a base (e.g., sodium carbonate) to directly generate 1-(4-bromophenyl)piperazine. Finally, 1-(4-bromophenyl)piperazine reacts with hydrochloric acid to synthesize 1-(4-bromophenyl)piperazine hydrochloride.

1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE Suppliers

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View Lastest Price from 1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
1-(4-Bromophenyl)piperazine hydrochloride 68104-62-1
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%+
Supply Ability
800 tons
Release date
2020-04-29
Career Henan Chemical Co
Product
1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE 68104-62-1
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
200kg
Release date
2018-12-24

68104-62-1, 1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDERelated Search:

Piperazine 1-(3-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE 1-(4-BROMO-PHENYL)-PIPERAZIN-2-ONE RARECHEM AN KD 2231 5-BROMO-2-(4-METHYLPIPERAZIN-1-YL)ANILINE DIHYDROCHLORIDE 1-(4-Bromophenyl)piperazine 1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE RARECHEM AN KB 2221

  • 1-(4-BROMOPHENYL)-PIPERAZINE HCL
  • 1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE
  • RARECHEM AH CK 0050
  • 1-(4-Bromophenyl)piperazine hydrochloride 98%
  • 1-(4-Bromophenyl)-piperazine x HCl
  • 1-(4-Bromophenyl)piperazin HCl
  • 1-(4-Bromophenyl)piperazineHydrochloride&gt
  • 1-(4-BROMOPHENYL)PIPERAZINE HYDROCHLORIDE ISO 9001：2015 REACH
  • 68104-62-1
  • C10H13BrN2ClH
  • C10H13BrN2.HCl
  • Pyrazines
  • Heterocycles
  • Piperazines