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TANNIC ACID

Product Name
TANNIC ACID
CAS No.
5424-20-4
Chemical Name
TANNIC ACID
Synonyms
TANNIN;TANNINUM;FEMA 3042;GERBSAURE;DIGALLIC ACID;CHINESE TANNIN;Tannic acid, β;CHINESE GALLOTANNIN;TANNIC ACID, 25 G+100 ML H2O;PENTA (M-DIGALLOYL) GLUCOSEN F
CBNumber
CB4305277
Molecular Formula
C76H52O46
Formula Weight
1701.21
MOL File
5424-20-4.mol
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TANNIC ACID Property

Melting point:
218 °C(lit.)
Density 
2.12±0.1 g/cm3(Predicted)
Flash point:
198 °C
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO:10.0(Max Conc. mg/mL);5.88(Max Conc. mM)
PBS (pH:7.2):0.3(Max Conc. mg/mL);0.176(Max Conc. mM)
form 
Solid
pka
6.00±0.50(Predicted)
color 
Off-white to light brown
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Safety

Safety Statements 
24/25
WGK Germany 
2
RTECS 
WW5075000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
21421
Product name
Gallotannin
Purity
≥98%
Packaging
5g
Price
$19
Updated
2023/01/06
Cayman Chemical
Product number
21421
Product name
Gallotannin
Purity
≥98%
Packaging
10g
Price
$30
Updated
2023/01/06
Cayman Chemical
Product number
21421
Product name
Gallotannin
Purity
≥98%
Packaging
25g
Price
$52
Updated
2023/01/06
Ambeed
Product number
A274873
Product name
Gallotannin
Purity
96+%
Packaging
5g
Price
$5
Updated
2021/12/16
Arctom
Product number
AS062938
Product name
Gallotannin
Purity
≥96%
Packaging
5g
Price
$5
Updated
2021/12/16
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TANNIC ACID Chemical Properties,Usage,Production

Description

Gallotannin is a polyphenol of gallic acid that has been found in various plants and has antioxidant, anti-inflammatory, antiviral, and antiproliferative biological activities. Gallotannin (1 μM) inhibits the intracellular production of reactive oxygen species (ROS) and DNA damage induced by phorbol 12-myristate 13-acetate (TPA; ) in human polymorphonuclear neutrophils (PMNs). It also decreases TPA-induced nitric oxide release by 90% from primary rat hepatocytes when used at a concentration of 0.5 mM. Gallotannin inhibits hepatitis C virus (HCV) entry into Huh7.5 human hepatoma cells (IC50 = 5.8 μM) and inhibits the proliferation of MDA-MB-231 and MCF-7 human breast cancer cells (IC50s = 2.5 and 4 μM, respectively). In a rat model of middle cerebral artery occlusion (MCAO), it increases superoxide dismutase (SOD1) protein levels and decreases the amount of proteins modified by malondialdehyde (MDA) in ischemic brain tissue when administered at a dose of 10 mg/kg.

Uses

Chinese gallotannin is a non-specific promiscuous α-amylase inhibitor with a Ki of 0.82 μg/mL for human salivary α-amylase. Chinese gallotannin can be used for the research of diabetes[1].

Definition

Any of several yellow organic compounds found in vegetable sources such as bark of trees, oak galls, and tea. They are used in tanning animal skins to make leather and as mordants in dyeing. Tannic acid (a type of tannin) is a white solid heterocyclic organic acid extracted from oak galls and used for making dyes and inks.

Definition

tannin: One of a group of complexorganic chemicals (see depsides) commonlyfound in leaves, unripe fruits,and the bark of trees. Their functionis uncertain though the unpleasanttaste may discourage grazing animals.Some tannins have commercialuses, notably in the production ofleather and ink.

References

[1] Szabó K, et al. Gallotannins are non-specific inhibitors of α-amylase: Aggregates are the active species taking part in inhibition. Chem Biol Drug Des. 2021 Feb;97(2):349-357. DOI:10.1111/cbdd.13787

TANNIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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TANNIC ACID Suppliers

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5424-20-4, TANNIC ACIDRelated Search:

Citric acid Hydrogen fluoride Glycerol Oxalic acid dihydrate Malic acid Phytic acid PETROLEUM ETHER Tannic acid

  • TANNIC ACID, 25 G+100 ML H2O
  • TANNIN
  • GERBSAURE
  • FEMA 3042
  • CHINESE GALLOTANNIN
  • CHINESE TANNIN
  • DIGALLIC ACID
  • beta-D-glucose pentakis[3,4-dihydroxy-5-[(3,4,5-trihydroxybenzoyl)oxy]benzoate]
  • β-D-Glucopyranose pentakis[3,4-dihydroxy-5-[(3,4,5-trihydroxybenzoyl)oxy]benzoate]
  • β-D-Glucopyranose, 1,2,3,4,6-pentakis[3,4-dihydroxy-5-[(3,4,5-trihydroxybenzoyl)oxy]benzoate]
  • PENTA (M-DIGALLOYL) GLUCOSEN F
  • TANNINUM
  • Gallotannin[Pentadigalloylglucose
  • (2S,3R,4S,5R,6R)-6-(((3,4-Dihydroxy-5-((3,4,5-trihydroxybenzoyl)oxy)benzoyl)oxy)methyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetrakis(3,4-dihydroxy-5-((3,4,5-trihydroxybenzoyl)oxy)benzoate)
  • [2,3-dihydroxy-5-[[(2R,3R,4S,5R,6S)-3,4,5,6-tetrakis[[3,4-dihydroxy-5-(3,4,5-trihydroxybenzoyl)oxybenzoyl]oxy]oxan-2-yl]methoxycarbonyl]phenyl] 3,4,5-trihydroxybenzoate
  • Tannic acid, β
  • 5424-20-4
  • C14H10O9
  • Chiral Building Blocks
  • Asymmetric Synthesis
  • Carboxylic Acids
  • Organic Building Blocks