Biotin-PEG2-Acid
- Product Name
- Biotin-PEG2-Acid
- CAS No.
- 1365655-89-5
- Chemical Name
- Biotin-PEG2-Acid
- Synonyms
- Biotin-PEG2-Acid;Biotin-PEG2-COOH;Biotin PEG2-C2-COOH;(+)-Biotin-PEG2-acid;(+)-Biotin-PEG2-CH2CH2COOH;3-(2-(2-(5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethoxy)ethoxy)propanoic acid;Propanoic acid, 3-[2-[2-[[5-[(3aR,4R,6aS)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethoxy]ethoxy]-, rel-
- CBNumber
- CB43062388
- Molecular Formula
- C17H29N3O6S
- Formula Weight
- 403.49
- MOL File
- 1365655-89-5.mol
Biotin-PEG2-Acid Property
- Boiling point:
- 752.2±60.0 °C(Predicted)
- Density
- 1.234±0.06 g/cm3(Predicted)
- storage temp.
- -20°C, protect from light, stored under argon
- solubility
- Soluble in DMSO, DMF
- pka
- 4.28±0.10(Predicted)
- form
- solid
- color
- White
- InChIKey
- SDOAIZRTYJIBBG-RMBTXETHNA-N
- SMILES
- C(O)(=O)CCOCCOCCNC(=O)CCCC[C@@H]1[C@]2([H])NC(=O)N[C@]2([H])CS1 |&1:18,19,25,r|
Safety
- HS Code
- 2918999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- BP-20613
- Product name
- Biotin-PEG2-acid
- Purity
- 98%
- Packaging
- 100mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- BP-20613
- Product name
- Biotin-PEG2-acid
- Purity
- 98%
- Packaging
- 500mg
- Price
- $390
- Updated
- 2021/12/16
- Product number
- POL0002383
- Product name
- BIOTIN-PEG2-ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $499.66
- Updated
- 2021/12/16
- Product number
- BP-20613
- Product name
- Biotin-PEG2-acid
- Purity
- 98%
- Packaging
- 1g
- Price
- $545
- Updated
- 2021/12/16
- Product number
- 246802
- Product name
- (+)-Biotin-PEG2-CH2CH2COOH
- Purity
- min.97%
- Packaging
- 250mg
- Price
- $180
- Updated
- 2021/12/16
Biotin-PEG2-Acid Chemical Properties,Usage,Production
Description
Biotin-PEG2-acid is reactive with amine-containing macromolecule. The hydrophilic PEG arm improves water solubility. The biotin groups serve as an affinity label towards the proteins avidin and streptavidin.
Uses
Biotin-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Biotin-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
IC 50
PEGs; Non-cleavable Linker
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005
Biotin-PEG2-Acid Preparation Products And Raw materials
Raw materials
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View Lastest Price from Biotin-PEG2-Acid manufacturers
- Product
- Biotin-PEG2-COOH 1365655-89-5
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-30