ChemicalBook > CAS DataBase List > Bis(4-hydroxyphenyl) Sulfone

Bis(4-hydroxyphenyl) Sulfone

Product Name
Bis(4-hydroxyphenyl) Sulfone
CAS No.
80-09-1
Chemical Name
Bis(4-hydroxyphenyl) Sulfone
Synonyms
BISPHENOL S;SDP;4,4-DIHYDROXYDIPHENYL SULPHONE;4,4-SULFONYLDIPHENOL;4,4'-SULFONYLDIPHENOL;-Hexabromodiphenyl Ether-13C6;50kg;bps1;3-dione;diphonec
CBNumber
CB4306294
Molecular Formula
C12H10O4S
Formula Weight
250.27
MOL File
80-09-1.mol
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Bis(4-hydroxyphenyl) Sulfone Property

Melting point:
245-250 °C (lit.)
Boiling point:
363.4°C (rough estimate)
Density 
1.366
vapor pressure 
<0.0001 Pa (20 °C)
refractive index 
1.5220 (estimate)
storage temp. 
Store below +30°C.
solubility 
1.1g/l
form 
Crystalline Powder
pka
7?+-.0.15(Predicted)
color 
White to grayish-green
PH
6.6-7.0 (100g/l, H2O, 20℃)
Odor
odorless
Water Solubility 
1.1 g/L (20 ºC)
λmax
295nm(H2O)(lit.)
BRN 
2052954
Stability:
Stable. Incompatible with strong bases, acid chloride, acid anhydrides, strong oxidizing agents.
InChIKey
VPWNQTHUCYMVMZ-UHFFFAOYSA-N
LogP
1.2 at 23℃
CAS DataBase Reference
80-09-1(CAS DataBase Reference)
EPA Substance Registry System
Phenol, 4,4'-sulfonylbis- (80-09-1)
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Safety

Hazard Codes 
Xi
Risk Statements 
36-36/37/38
Safety Statements 
26-39-36-37
WGK Germany 
2
RTECS 
SM8925000
Autoignition Temperature
>=400 °C
TSCA 
Yes
HS Code 
29309070
Hazardous Substances Data
80-09-1(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: 2830 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H303May be harmfulif swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H402Harmful to aquatic life

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
103039
Product name
4,4′-Sulfonyldiphenol
Purity
98%
Packaging
100g
Price
$47.1
Updated
2024/03/01
Sigma-Aldrich
Product number
103039
Product name
4,4′-Sulfonyldiphenol
Purity
98%
Packaging
500g
Price
$165
Updated
2024/03/01
Sigma-Aldrich
Product number
8.03258
Product name
Bis(4-hydroxyphenyl) sulfone
Purity
for synthesis
Packaging
100g
Price
$43.2
Updated
2023/06/20
Sigma-Aldrich
Product number
8.03258
Product name
Bis(4-hydroxyphenyl) sulfone
Purity
for synthesis
Packaging
500g
Price
$85.4
Updated
2023/06/20
TCI Chemical
Product number
B0495
Product name
Bis(4-hydroxyphenyl) Sulfone
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$21
Updated
2024/03/01
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Bis(4-hydroxyphenyl) Sulfone Chemical Properties,Usage,Production

Description

Bisphenol S, also known as 4,4'-Sulfonyldiphenol, abbreviated as BPS, is a synthetic bisphenol (BP) compound. It was originally used as a safe alternative to bisphenol A and is present in many household products, including food packaging, beverage containers, lotions, toys, plastic PVC floors and water pipes[1]. However, current studies have found that BPS does not seem to be very safe and may damage the function of melanocytes[2]. Higher BPS exposure is also associated with increased serum uric acid concentrations, and this association is more obvious in boys, which poses certain health hazards[3].

Chemical Properties

White needle-like crystals. Freely soluble in aliphatic hydrocarbons, soluble in alcohols and ethers, slightly soluble in aromatics, insoluble in water. Bisphenol S molecule contains two hydroxyl groups and a strong electron-absorbing sulfone group, so the acidity is stronger than other phenols.

Uses

4,4'-Sulfonyldiphenol is commonly used as a reactant in epoxy reactions and is also used as a latent thermal catalyst for epoxy resin.

Uses

Bis(4-hydroxyphenyl) Sulfone is commonly used as a reactant in epoxy reactions and is also used as a latent thermal catalyst for epoxy resin.

Preparation

A process for the preparation of bis(4-hydroxyphenyl)sulfone by reacting phenol with sulfuric acid in the presence of a solvent at from 130° to 220° C and in the presence or absence of a sulfonating assistant. 

Definition

ChEBI: 4,4'-sulfonyldiphenol is a sulfone that is diphenyl sulfone in which both of the para hydrogens have been replaced by hydroxy groups. It has a role as a metabolite and an endocrine disruptor. It is a sulfone and a bisphenol. It is functionally related to a diphenyl sulfone.

General Description

Bisphenol S (BPS), belonging to the class of bisphenols, is a structural analog of bisphenol A (BPA), used in a variety of industrial applications and products marketed as BPA-free. It is commonly identified in food and beverages, environmental samples, biological matrices, etc. It is also reported to be used in the production of epoxy resins. BPS is also found to be stable compared to BPA at elevated temperature and sunlight conditions.

Health Hazard

Although there is no direct link established between bis(4-hydroxyphenyl) sulfone(BPS) and cardiac disease, it is thought that bis(4-hydroxyphenyl) sulfone may operate by a similar mechanism to BPA and could cause cardiac toxicity.

Flammability and Explosibility

Non flammable

References

[1] J. APAU  Eric A  Akwasi Acheampong. Exposure to bisphenol A, bisphenol F, and bisphenol S can result in obesity in human body[J]. Cogent Chemistry, 2018. DOI:10.1080/23312009.2018.1506601.
[2] GOENKA S. Disruption of functions of primary human neonatal melanocytes cultured in the presence of bisphenol A and its analogs bisphenol F and bisphenol S[J]. Journal of hazardous materials letters, 2024, 5: Article 100110. DOI:10.1016/j.hazl.2024.100110.
[3] Y. LEE. Relationship between bisphenol A, bisphenol S, and bisphenol F and serum uric acid concentrations among school-aged children[J]. PLoS ONE, 2022. DOI:10.1371/journal.pone.0268503.

Bis(4-hydroxyphenyl) Sulfone Preparation Products And Raw materials

Raw materials

Preparation Products

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Bis(4-hydroxyphenyl) Sulfone Suppliers

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View Lastest Price from Bis(4-hydroxyphenyl) Sulfone manufacturers

Shanghai Qyubiotech Co., Ltd.
Product
Bis(4-hydroxyphenyl) Sulfone 80-09-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%+
Supply Ability
10000kgs per Month
Release date
2023-08-16
Jinan Finer Chemical Co., Ltd
Product
4,4'-Sulfonyldiphenol 80-09-1
Price
US $0.00/Kg/Bag
Min. Order
1KG
Purity
99%
Supply Ability
5000mt/year
Release date
2021-08-05
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Bis (4-hydroxyphenyl) Sulfone 80-09-1
Price
US $85.00-35.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-24

80-09-1, Bis(4-hydroxyphenyl) SulfoneRelated Search:

Triclosan 4-Cyanophenol 9,9-Bis(4-hydroxyphenyl)fluorene Bisphenol A Tetradifon 4,4'-Dichlorodiphenyl sulfone Diphenyl sulfone 4,4'-Diaminodiphenylsulfone Tetrabromobisphenol A 4,4'-Sulphonylbis(2,6-dibromophenol) tert-Butyl acrylate 4,4'-DIHYDROXYDIPHENYLMETHANE 3,5-Dihydroxybenzoic acid Phenyl sulfoxide 4,4'-(4,4'-ISOPROPYLIDENEDIPHENOXY)BIS(PHTHALIC ANHYDRIDE) 2,2'-Diamino-4,4'-sulfonyldiphenol Bis[4-(4-aminophenoxy)phenyl]sulfone BIS(4-HYDROXY-3,5-DIMETHYLPHENYL) SULFONE

  • BIS(4-HYDROXYPHENYL) SULPHONE
  • BIS(4-HYDROXYPHENYL) SULFONE
  • 4-HYDROXYPHENYL SULFONE
  • 4,4-DIHYDROXYDIPHENYL SULPHONE
  • 4,4'-DIHYDROXYDIPHENYLSULPHONE
  • 4,4'-DIHYDROXYDIPHENYL SULFONE
  • 4,4-DIHYDROXYDIPHENYL SULFONE
  • 4,4'-SULFONYLDIPHENOL
  • 4,4-SULFONYLDIPHENOL
  • -Dimethoxybenzhydrol
  • -Hexabromodiphenyl Ether-13C6
  • -Dimethoxydibenzoyl
  • -Bisbenzyl alcohol 99+%
  • 4,4'-Sulfonyldiphenol (BPS)
  • -Dinitro-2-biphenylamine
  • 3-dione
  • -bis(trifluoromethyl)biphenyl
  • 6-Pentabromodiphenyl Ether-13C6
  • Bisphenol S/4,4'-Sulfonyldiphenol/BPS
  • -[1-(2-Chloroethyl)-2-phenyl-1,2-ethenediyl]-4-O-pivaloyl-bisphenol
  • -Bis(isocyanatophenyl)oxide
  • -Methoxyphenoxy)benzaldehyde
  • -Dichlorobenzil 99+% (GC)
  • -Oxydibenzenesulfonyl hydrazide
  • -Isopropoxyphenyl)phenylboronic acid
  • -Bis(methoxycarbonyl)biphenyl
  • -Oxydiphenol
  • -Thiobis(2-tert-butyl-5-methylphenol)
  • -Dibromo-p-terphenyl
  • -Diazoaminodibenzenesulfonic Acid Disodium Salt
  • -(Iminobis(methylene))bis-phenol
  • -Tetranitrobenzophenone
  • -(1,5-Pentanediyldiimino)dibenzoic acid
  • -Dichlorobenzophenone 99+% (HPLC)
  • -Dimethoxybenzil
  • -(2-Methoxyethyl)phenoxy)methyl]phenylboronic acid
  • -Dimethyltriphenylamine
  • -(Hexafluoroisopropylidene)diphthalic anhydride 99.5+% (HPLC)
  • -Bis(2-sulfostyryl)biphenyl disodium
  • -Methyl-methylene Trazodone Dimer-d12
  • -Dibromooctafluorobiphenyl
  • 6-Pentabromodiphenyl Ether
  • -dimethoxybenzhydryl-D-glutamine
  • -Hydroxyphenyl)amino-6,7-dimethoxyquinazoline
  • -Methylenebis(cyclohexylamine)
  • -Methylenedi-o-toluidine
  • -Dithiobiscinnamic acid
  • -Diisooctanyldiphenylamine
  • -Allyloxycarbonylpiperizino)phenylboronic Acid Pinacol Ester
  • -(Hexafluoroisopropylidene)diphthalic anhydride
  • -Isopentyloxyphenyl)phenylboronic Acid
  • -dimethoxybenzhydryl-L-glutamine 4-alkoxybenzyl alcohol resin
  • -Diapo-lycopenedial
  • -biphenyl]-3-carboxylate
  • -Dihydroxytetraphenylmethane
  • -(2,5-Furandiyl)bis-benzonitrile
  • -Dithiopyridine
  • -Methylenebis[N,N-dimethylcyclohexanamine]