4-Cyanophenol

Product Name: 4-Cyanophenol
CAS No.: 767-00-0
Chemical Name: 4-Cyanophenol
Synonyms: 4-HYDROXYBENZONITRILE;4-HYDROXYBENZOHYDRAZIDE;P-CYANOPHENOL;PARA-CYANOPHENOL;Hydroxybenzonitrile;Benzonitrile, 4-hydroxy-;PHBN;P-nitrile;AKOS 217-25;AKOS B004225
CBNumber: CB6681698
Molecular Formula: C7H5NO
Formula Weight: 119.12
MOL File: 767-00-0.mol

More

Less

4-Cyanophenol Property

Melting point:: 110-113 °C(lit.)
Boiling point:: 146 °C / 2mmHg
Density: 1.1871 (rough estimate)
refractive index: 1.5800 (estimate)
storage temp.: Inert atmosphere,Room Temperature
solubility: methanol: 0.1 g/mL, clear
form: Crystalline Powder
pka: 7.97(at 25℃)
color: Off-white to beige-gray
Water Solubility: slightly soluble
BRN: 386130
Stability:: Stable. Incompatible with strong oxidizing agents.
InChI: 1S/C7H5NO/c8-5-6-1-3-7(9)4-2-6/h1-4,9H
InChIKey: CVNOWLNNPYYEOH-UHFFFAOYSA-N
SMILES: Oc1ccc(cc1)C#N
CAS DataBase Reference: 767-00-0(CAS DataBase Reference)
NIST Chemistry Reference: 4-Hydroxybenzoic acid nitrile(767-00-0)
EPA Substance Registry System: Benzonitrile, 4-hydroxy- (767-00-0)

More

Less

Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36/37/38
Safety Statements: 26-36-45-24/25
WGK Germany: 3
RTECS: DI4375000
Hazard Note: Irritant
TSCA: TSCA listed
HS Code: 29269095
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C94009
Product name: 4-Cyanophenol
Purity: 95%
Packaging: 5g
Price: $37.5
Updated: 2025/07/31

TCI Chemical

Product number: C0842
Product name: 4-Hydroxybenzonitrile
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $22
Updated: 2025/07/31

TCI Chemical

Product number: C0842
Product name: 4-Hydroxybenzonitrile
Purity: >98.0%(GC)(T)
Packaging: 500g
Price: $209
Updated: 2025/07/31

Sigma-Aldrich

Product number: C94009
Product name: 4-Cyanophenol
Purity: 95%
Packaging: 25g
Price: $53.7
Updated: 2025/07/31

Sigma-Aldrich

Product number: C94009
Product name: 4-Cyanophenol
Purity: 95%
Packaging: 100g
Price: $73
Updated: 2025/07/31

More

Less

4-Cyanophenol Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder or chips. 4-Hydroxybenzonitrile [767-00-0], 4-cyanophenol, 1-cyano-4-hydroxybenzene, Mr 119.2, forms colorless crystals of mp 113℃. 4-Hydroxybenzonitrile is produced by reaction of 4-bromophenol with copper (I) cyanide, by ammoxidation of p-cresol, by reaction of 4-chlorobenzonitrile with sodium methoxide, or by the catalyzed gas phase reaction of ethyl 4-hydroxybenzoate with ammonia. The nitrile is used for the production of the herbicides 3,5-dibromo- and 3,5-diiodo-4- hydroxybenzonitrile (Bromoxynil, Ioxynil, May & Baker).

Uses

Intermediates of Liquid Crystals

Uses

4-Cyanophenol is a precursor for the synthesis of a vasodilator, Levcromakalim. Bromination of 4-cyanophenol results in bromoxynil, a commercial herbicide. It can also be used as a component of deep eutectic solvent (DES) mixture.

Preparation

4-Cyanophenol is produced by reaction of 4-bromophenol with copper (I) cyanide, by ammoxidation of p-cresol, by reaction of 4-chlorobenzonitrile with sodium methoxide, or by the catalyzed gas phase reaction of ethyl 4-hydroxybenzoate with ammonia.

Definition

ChEBI: 4-cyanophenol is a member of phenols. It has a role as an EC 1.4.3.4 (monoamine oxidase) inhibitor. It is functionally related to a benzonitrile.

Synthesis Reference(s)

The Journal of Organic Chemistry, 39, p. 3343, 1974 DOI: 10.1021/jo00937a007

Purification Methods

Crystallise the phenol from pet ether, *benzene or water and keep it under vacuum over P2O5. [Bernasconi & Paschelis J Am Chem Soc 108 2969 1986.] [Beilstein 10 H 167, 10 IV 441.]

4-Cyanophenol Preparation Products And Raw materials

Raw materials

4-Hydroxybenzoic acid Phosphorus pentasulfide Urea Water 4-Hydroxybenzaldehyde Hydroxylamine hydrochloride Benzyl benzoate

Preparation Products

4-Hydroxybenzamidine hydrochloride 2-(4-CYANOPHENOXY)-2-METHYLPROPANOIC ACID Bromoxynil 2-(4-HYDROXYPHENYL)-5-PYRIMIDINOL CYANOPHOS

More

Less

4-Cyanophenol Suppliers

Americas 1 Belgium 3 Canada 2 China 521 Europe 5 France 4 Germany 15 India 30 Japan 6 Slovakia 1 South Korea 1 Switzerland 2 The Netherlands 1 Ukraine 2 United Kingdom 23 United States 72 Global 689

NANJING CHEMFIRST CO.,LTD.

Tel: 025-87780427 15850602248
Email: info@chemfs.com
Country: China
ProdList: 13
Advantage: 58

Wuxi enqiao Pharmaceutical Technology Co., Ltd

Tel: 0510-83591909 18018392058
Fax: 0510-83591909
Email: info@enbridgepharm.com
Country: China
ProdList: 242
Advantage: 58

Jiangsu Runfeng Synthetic Technology Co., Ltd.

Tel: 0513-66017678 18551497631
Email: 507167383@qq.com
Country: China
ProdList: 5000
Advantage: 58

Jinan Pengyao Technology Co., Ltd.

Tel: 18668967061
Email: 353847264@qq.com
Country: China
ProdList: 293
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
Advantage: 66

future industrial shanghai co., ltd

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: sales@jonln.com
Country: China
ProdList: 1995
Advantage: 65

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TAIYUAN RHF CO.,LTD.

Tel: +86 351 7031519
Fax: +86 351 7031519
Email: sales@RHFChem.com
Country: China
ProdList: 2338
Advantage: 56

More

Less

View Lastest Price from 4-Cyanophenol manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 4-Cyanophenol 767-00-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 10000KGS
Release date: 2025-06-24

Hebei Chuanghai Biotechnology Co., Ltd

Product: 4-Cyanophenol 767-00-0
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5tons
Release date: 2024-12-02

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: 4-Cyanophenol 767-00-0
Price: US $70.00-25.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-06-05

767-00-0, 4-CyanophenolRelated Search:

4'-Hydroxyacetophenone 4-Nitrobenzonitrile Glycolic acid 4-Methoxyphenol 4-Hydroxybenzamide Hydroxy silicone oil 4-Hydroxybenzaldehyde 4-Hydroxybenzoic acid Hydroxyapatite Benzonitrile Methylparaben 4-Hydrazinobenzoic acid hydrochloride 4-Hydrazinylbenzoic acid 4-METHOXY-1-NAPHTHONITRILE 2,3,4-TRIMETHOXYBENZONITRILE 2,4,6-Trimethoxybenzonitrile 4-Hydroxy-3-methoxybenzonitrile 2,4-Dimethoxybenzonitrile

p-hydroxy benzonitrile，p-cyano phenol

4-HYDROXYBENZONITRILE FOR SYNTHESIS

AKOS B004225

AKOS 217-25

4-CYANOPHENOL

4-HYDROXYBENZONITRILE

CYANOPHENOL(4-)

P-CYANOPHENOL

P-HYDROXYBENZONITRILE

p-Cyanolphenol

p-hydroxy-benzonitril

4-Hydroxybenzenecarbonitrile

P-nitrile

Right hydroxybenzonitrile

4-Cyanophenol, 99% 100GR

4-Cyanophenol, 99% 25GR

Febuxostat-21

p-Hydroxybenzonitrile 4-Cyanophenol

TIMTEC-BB SBB008054

P-Cyanophenol(4-HydroxyBenzonitrile)

4-Cyanophenol99%

4-Hydroxybenzonitrile, 98+%

4-Cyanophenol,98+%

4-HYDROXYBENZONITRILE (P-HYDROXYBENZONITRILE)

4-CYANOPHENOL(4-HYDROXYBENZONITRILE)

PARA-CYANOPHENOL

p-Hydroxybenzonitrile, 4-Hydroxybenzonitrile

Hydroxybenzonitrile

4-HYDROXYBENZONITRILE PESTANAL, 250 MG

4-HYDROXYBENZOHYDRAZIDE

The cyano phenol

4-Hydroxybenzo

4-Cyanolphenol

4-hydroxy-benzonitril

4-Cyanophenol, 97+%

Benzonitrile, 4-hydroxy-

Benzonitrile, p-hydroxy-

Benzonitrile,4-hydroxy-

4-Hydroxybenzonitrile &gt

Hydroxyphenonitrile

P-Hydroxybenzonitrite

4-Cyanophenol ISO 9001：2015 REACH

4-Cyanophenol (Febuxostat Impurity)

4-Cyanophenol P-Cyanophenol

4-Cyanophenol?New

4-Hydroxybenzonitrile, 95%

PHBN

767-00-0

676-00-0

767-00-1

CNC6H4OH

Nitrogen Compounds

Organic Building Blocks

Cyanides/Nitriles

Benzonitriles (Building Blocks for Liquid Crystals)

Building Blocks for Liquid Crystals

Building Blocks

C6 to C7