4-Hydrazinobenzoic acid hydrochloride
- Product Name
- 4-Hydrazinobenzoic acid hydrochloride
- CAS No.
- 24589-77-3
- Chemical Name
- 4-Hydrazinobenzoic acid hydrochloride
- Synonyms
- BIO-FARMA BF001082;4-Hydrazinobenzoic;4-Hydrazinobenzoic a;LABOTEST-BB LT01596126;4-HYDRAZINOBENZOIC ACID HCL;P-CARBOXYPHENYL HYDRAZINE HCL;Hydrazinobenzoic acid hydrochlori;P HYDRAZINOBENZOIC ACID HYDROCHLORIDE;4-HYDRAZINOBENZOIC ACID HYDROCHLORIDE;Carboxy phenylhydrazine hydrochloride
- CBNumber
- CB3783221
- Molecular Formula
- C7H9ClN2O2
- Formula Weight
- 188.61
- MOL File
- 24589-77-3.mol
4-Hydrazinobenzoic acid hydrochloride Property
- Melting point:
- 253 °C (dec.)(lit.)
- storage temp.
- 2-8°C
- solubility
- DMSO (Slightly), Methanol (Sparingly)
- form
- Solid
- color
- White to Off-White
- Water Solubility
- Soluble in water.
- InChI
- InChI=1S/C7H8N2O2.ClH/c8-9-6-3-1-5(2-4-6)7(10)11;/h1-4,9H,8H2,(H,10,11);1H
- InChIKey
- XHLQMKQBCHYRLC-UHFFFAOYSA-N
- SMILES
- C1(C(=O)O)=CC=C(NN)C=C1.Cl
- CAS DataBase Reference
- 24589-77-3(CAS DataBase Reference)
- EPA Substance Registry System
- Benzoic acid, 4-hydrazino-, monohydrochloride (24589-77-3)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 433829
- Product name
- 4-Hydrazinobenzoic acid hydrochloride
- Purity
- 98%
- Packaging
- 25g
- Price
- $44.4
- Updated
- 2025/07/31
- Product number
- H716575
- Product name
- 4-Hydrazinobenzoic acid hydrochloride
- Packaging
- 250mg
- Price
- $40
- Updated
- 2021/12/16
- Product number
- H716575
- Product name
- 4-Hydrazinobenzoic acid hydrochloride
- Packaging
- 10g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- H716575
- Product name
- 4-Hydrazinobenzoic acid hydrochloride
- Packaging
- 1g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- AK-79152
- Product name
- 4-Hydrazinylbenzoicacidhydrochloride
- Purity
- 98%
- Packaging
- 100g
- Price
- $51
- Updated
- 2021/12/16
4-Hydrazinobenzoic acid hydrochloride Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystal powder
Uses
4-Hydrazinobenzoic acid hydrochloride is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields. It may be used for the preparation of 4-(3-(2-(tert-butoxycarbonylamino)ethyl)-5-hydroxy-1H-pyrazol-1-yl)benzoic acid.
General Description
4-Hydrazinobenzoic acid (p-Hydrazinobenzoic acid, HBA) has been reported as an ingredient of the cultivated mushroom Agaricus bisporus. It is carcinogenic to rodents. Mechanism of DNA damage by 4-hydrazinobenzoic acid has been studied by using 32P-labeled DNA fragments obtained from the human p53 and p16 tumor suppressor genes. It may be used for the preparation of 4-(3-(2-(tert-butoxycarbonylamino)ethyl)-5-hydroxy-1H-pyrazol-1-yl)benzoic acid.
Synthesis
To 600 ml beaker add water 150 ml, stirring, add p-aminobenzoic acid 27.4 g, 10N hydrochloric acid 57.5 ml, after cooling the solution to 0 ??, slowly add sodium nitrite solution (from 15 grams of sodium nitrite and 30 ml of water to formulate), add the end of the system, adjust the system pH for 1-2, control the temperature of the reaction system 5 ??, the reaction for 20 minutes, filtration and retention of the filtrate. Add 200 ml of water to a 1000 ml beaker, add 64 g of sodium metabisulfite and 78 g of sodium hydroxide with stirring, at this time, the solution pH was 7, the solution temperature was 35 ?? C. After the solution was cooled down to 15-18 ?? C, the above filtrate was added slowly, and the temperature of the solution was 20 ?? C when it was added, the pH was 7, and the reaction was carried out for 30 minutes, and then the temperature was raised to 50-60 ?? C, and 115 ml of hydrochloric acid was added to it, and the temperature continued to be raised to 97-100 ?? C, and the reaction was continued to be carried out for 20 minutes. Elevate the temperature to 97-100 ?? C, and at this temperature reaction for 30 minutes after adding 7 grams of activated carbon, decolorization after 90 ?? C filtration to retain the filtrate, cooled to 15 ?? C, add hydrochloric acid, the material precipitation, filtration, pumping dry to get the 4-carboxyphenylhydrazine hydrochloride product. The purity of 4-carboxyphenylhydrazine hydrochloride was 98.92% as measured by high performance liquid chromatography.
4-Hydrazinobenzoic acid hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Hydrazinobenzoic acid hydrochloride manufacturers
- Product
- 4-Hydrazinobenzoic acid hydrochloride 24589-77-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-11-08
- Product
- 4-Hydrazinobenzoic acid hydrochloride 24589-77-3
- Price
- US $10.00-0.80/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-01-12
- Product
- ?4-hydrazinylbenzoic acid,hydrochloride 24589-77-3
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2023-06-30