4-Cyanophenol
- Product Name
- 4-Cyanophenol
- CAS No.
- 767-00-0
- Chemical Name
- 4-Cyanophenol
- Synonyms
- 4-HYDROXYBENZONITRILE;4-HYDROXYBENZOHYDRAZIDE;P-CYANOPHENOL;PARA-CYANOPHENOL;Hydroxybenzonitrile;Benzonitrile, 4-hydroxy-;P-nitrile;AKOS 217-25;AKOS B004225;4-CYANOPHENOL
- CBNumber
- CB6681698
- Molecular Formula
- C7H5NO
- Formula Weight
- 119.12
- MOL File
- 767-00-0.mol
4-Cyanophenol Property
- Melting point:
- 110-113 °C(lit.)
- Boiling point:
- 146 °C / 2mmHg
- Density
- 1.1871 (rough estimate)
- refractive index
- 1.5800 (estimate)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- methanol: 0.1 g/mL, clear
- form
- Crystalline Powder
- pka
- 7.97(at 25℃)
- color
- Off-white to beige-gray
- Water Solubility
- slightly soluble
- BRN
- 386130
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- CAS DataBase Reference
- 767-00-0(CAS DataBase Reference)
- NIST Chemistry Reference
- 4-Hydroxybenzoic acid nitrile(767-00-0)
- EPA Substance Registry System
- Benzonitrile, 4-hydroxy- (767-00-0)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26-36-45-24/25
- WGK Germany
- 3
- RTECS
- DI4375000
- Hazard Note
- Irritant
- TSCA
- Yes
- HS Code
- 29269095
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C94009
- Product name
- 4-Cyanophenol
- Purity
- 95%
- Packaging
- 5g
- Price
- $36.4
- Updated
- 2024/03/01
- Product number
- C0842
- Product name
- 4-Hydroxybenzonitrile
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $23
- Updated
- 2024/03/01
- Product number
- C0842
- Product name
- 4-Hydroxybenzonitrile
- Purity
- >98.0%(GC)(T)
- Packaging
- 500g
- Price
- $220
- Updated
- 2024/03/01
- Product number
- A15803
- Product name
- 4-Hydroxybenzonitrile, 98+%
- Packaging
- 50g
- Price
- $63.65
- Updated
- 2024/03/01
- Product number
- A15803
- Product name
- 4-Hydroxybenzonitrile, 98+%
- Packaging
- 100g
- Price
- $105.65
- Updated
- 2024/03/01
4-Cyanophenol Chemical Properties,Usage,Production
Chemical Properties
white crystalline powder or chips. 4-Hydroxybenzonitrile [767-00-0], 4-cyanophenol, 1-cyano-4-hydroxybenzene, Mr 119.2, forms colorless crystals of mp 113℃. 4-Hydroxybenzonitrile is produced by reaction of 4-bromophenol with copper (I) cyanide, by ammoxidation of p-cresol, by reaction of 4-chlorobenzonitrile with sodium methoxide, or by the catalyzed gas phase reaction of ethyl 4-hydroxybenzoate with ammonia. The nitrile is used for the production of the herbicides 3,5-dibromo- and 3,5-diiodo-4- hydroxybenzonitrile (Bromoxynil, Ioxynil, May & Baker).
Uses
Intermediates of Liquid Crystals
Uses
4-Cyanophenol is a precursor for the synthesis of a vasodilator, Levcromakalim. Bromination of 4-cyanophenol results in bromoxynil, a commercial herbicide. It can also be used as a component of deep eutectic solvent (DES) mixture.
Preparation
4-Cyanophenol is produced by reaction of 4-bromophenol with copper (I) cyanide, by ammoxidation of p-cresol, by reaction of 4-chlorobenzonitrile with sodium methoxide, or by the catalyzed gas phase reaction of ethyl 4-hydroxybenzoate with ammonia.
Definition
ChEBI: 4-cyanophenol is a member of phenols. It has a role as an EC 1.4.3.4 (monoamine oxidase) inhibitor. It is functionally related to a benzonitrile.
Synthesis Reference(s)
The Journal of Organic Chemistry, 39, p. 3343, 1974 DOI: 10.1021/jo00937a007
Purification Methods
Crystallise the phenol from pet ether, *benzene or water and keep it under vacuum over P2O5. [Bernasconi & Paschelis J Am Chem Soc 108 2969 1986.] [Beilstein 10 H 167, 10 IV 441.]
4-Cyanophenol Preparation Products And Raw materials
Raw materials
Preparation Products
4-Cyanophenol Suppliers
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- --
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- y.barysheva@ukrorgsynth.com
- Country
- Ukraine
- ProdList
- 6230
- Advantage
- 38
- Tel
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- Sales@casorganic.com
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- Ukraine
- ProdList
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View Lastest Price from 4-Cyanophenol manufacturers
- Product
- 4-Cyanophenol 767-00-0
- Price
- US $70.00-25.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-06-05
- Product
- 4-Cyanophenol 767-00-0
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 5tons
- Release date
- 2024-12-02
- Product
- 4-Cyanophenol P-Cyanophenol 767-00-0
- Price
- US $19.00/KG
- Min. Order
- 1KG
- Purity
- 99.%
- Supply Ability
- 50 ton
- Release date
- 2024-08-22