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4-Hydroxy-3-methoxybenzonitrile

Product Name
4-Hydroxy-3-methoxybenzonitrile
CAS No.
4421-08-3
Chemical Name
4-Hydroxy-3-methoxybenzonitrile
Synonyms
AKOS B004154;VANILO NITRILE;VANILLONITRILE;4-Hydroxy-3-methoxyb;4-Cyano-2-methoxyphenol;2-methyl-3-phenyl-3-pentanol;3-Methoxy-4-Hydroxybenzonitrle;4-Hydroxy-3-Methoxybenzonitile;3-Methoxy-4-Hydroxybenzonitril;4-Hydroxy-3-methoxybenzonitriL
CBNumber
CB5114702
Molecular Formula
C8H7NO2
Formula Weight
149.15
MOL File
4421-08-3.mol
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4-Hydroxy-3-methoxybenzonitrile Property

Melting point:
85-87 °C (lit.)
Boiling point:
270.21°C (rough estimate)
Density 
1.2517 (rough estimate)
refractive index 
1.5320 (estimate)
storage temp. 
Sealed in dry,Room Temperature
form 
powder to crystal
pka
7.84±0.18(Predicted)
color 
White to Light yellow to Light orange
InChI
1S/C8H7NO2/c1-11-8-4-6(5-9)2-3-7(8)10/h2-4,10H,1H3
InChIKey
QJRWLNLUIAJTAD-UHFFFAOYSA-N
SMILES
COc1cc(ccc1O)C#N
LogP
1.551 (est)
CAS DataBase Reference
4421-08-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-37/39-36/37/39
RIDADR 
3439
WGK Germany 
3
HazardClass 
6.1
PackingGroup 
III
HS Code 
29269090
Storage Class
11 - Combustible Solids
Hazard Classifications
Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
162604
Product name
4-Hydroxy-3-methoxybenzonitrile
Purity
98%
Packaging
25G
Price
$45.3
Updated
2025/07/31
TCI Chemical
Product number
H0620
Product name
4-Hydroxy-3-methoxybenzonitrile
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$45
Updated
2025/07/31
TCI Chemical
Product number
H0620
Product name
4-Hydroxy-3-methoxybenzonitrile
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$176
Updated
2025/07/31
TRC
Product number
H972660
Product name
4-Hydroxy-3-methoxybenzonitrile
Packaging
500mg
Price
$45
Updated
2021/12/16
Matrix Scientific
Product number
089698
Product name
4-Hydroxy-3-methoxybenzonitrile
Purity
98%
Packaging
5g
Price
$38
Updated
2021/12/16
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4-Hydroxy-3-methoxybenzonitrile Chemical Properties,Usage,Production

Chemical Properties

beige crystalline powder

Uses

4-Hydroxy-3-methoxybenzonitrile was used in the synthesis of 1,5-bis(4-cyano-2-methoxyphenoxy)-3-oxapentane.

Synthesis Reference(s)

Journal of the American Chemical Society, 70, p. 2293, 1948 DOI: 10.1021/ja01186a514

General Description

4-Hydroxy-3-methoxybenzonitrile on treatment with sodium perborate yields 4-hydroxy-3-methoxybenzamide.

4-Hydroxy-3-methoxybenzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Hydroxy-3-methoxybenzonitrile Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
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Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
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TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
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Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
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61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
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66
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
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Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070 13913916777;
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15778
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Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
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64
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
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View Lastest Price from 4-Hydroxy-3-methoxybenzonitrile manufacturers

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
4-Hydroxy-3-methoxybenzonitrile 4421-08-3
Price
US $100.00-75.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000Ton
Release date
2024-08-13
Career Henan Chemical Co
Product
4-Hydroxy-3-methoxybenzonitrile 4421-08-3
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2019-05-24

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