ChemicalBook > CAS DataBase List > TM5007

TM5007

Product Name: TM5007
CAS No.: 342595-05-5
Chemical Name: TM5007
Synonyms: TM5007;TM 5007,inhibit,TM5007,PAI-1,Plasminogen activator inhibitor-1,Inhibitor,TM-5007;[2,3'-Bithiophene]-4'-carboxylic acid, 5',5'''-[(1,6-dioxo-1,6-hexanediyl)diimino]bis-;5'-[5-({4'-carboxy-[2,3'-bithiophen]-5'-yl}carbamoyl)pentanamido]-[2,3'-bithiophene]-4'-carboxylic acid
CBNumber: CB43067585
Molecular Formula: C24H20N2O6S4
Formula Weight: 560.69
MOL File: 342595-05-5.mol

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TM5007 Property

Boiling point:: 781.7±60.0 °C(Predicted)
Density: 1.544±0.06 g/cm3(Predicted)
pka: 3.93±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

AK Scientific

Product number: SYN5237
Product name: TM5007
Packaging: 10mg
Price: $320
Updated: 2021/12/16

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TM5007 Chemical Properties,Usage,Production

Uses

TM5007 is a poent and orally active inhibitor of plasminogen activator inhibitor-1 (PAI-1) with an IC50 of 29 μM. TM5007 enhance fibrinolysis activity and inhibits coagulation. TM5007 also prevents the fibrotic process initiated by bleomycin in mouse lung[1].

References

[1] Izuhara Y, et al. Inhibition of plasminogen activator inhibitor-1: its mechanism and effectiveness on coagulation and fibrosis. Arterioscler Thromb Vasc Biol. 2008 Apr;28(4):672-7. DOI:10.1161/ATVBAHA.107.157479

TM5007 Preparation Products And Raw materials

Raw materials

Preparation Products

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342595-05-5, TM5007Related Search:

TM5441 TM 5275

TM5007

[2,3'-Bithiophene]-4'-carboxylic acid, 5',5'''-[(1,6-dioxo-1,6-hexanediyl)diimino]bis-

TM 5007,inhibit,TM5007,PAI-1,Plasminogen activator inhibitor-1,Inhibitor,TM-5007

5'-[5-({4'-carboxy-[2,3'-bithiophen]-5'-yl}carbamoyl)pentanamido]-[2,3'-bithiophene]-4'-carboxylic acid

342595-05-5