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URB602

Product Name
URB602
CAS No.
565460-15-3
Chemical Name
URB602
Synonyms
URB602;URB 602;URB-602;URB602, 10 mM in DMSO;N-[1,1'-Biphenyl]-3-yl-;cyclohexyl biphenyl-3-ylcarbaMate;cyclohexyl N-(3-phenylphenyl)carbamate;Cyclohexyl [1,1'-biphenyl]-3-ylcarbamate;Monoacylglycerol Lipase Inhibitor, URB602;URB602, monoglycerol lipase (MGL) inhibitor;Biphenyl-3-yl Carbamic Acid, Cyclohexyl Ester
CBNumber
CB4311681
Molecular Formula
C19H21NO2
Formula Weight
295.38
MOL File
565460-15-3.mol
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URB602 Property

Melting point:
122-123°C
storage temp. 
2-8°C
solubility 
DMSO: >10mg/mL
form 
powder
color 
white to off-white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10007457
Product name
URB602
Purity
≥98%
Packaging
5mg
Price
$36
Updated
2024/03/01
Cayman Chemical
Product number
10007457
Product name
URB602
Purity
≥98%
Packaging
10mg
Price
$66
Updated
2024/03/01
Cayman Chemical
Product number
10007457
Product name
URB602
Purity
≥98%
Packaging
50mg
Price
$274
Updated
2024/03/01
Cayman Chemical
Product number
10007457
Product name
URB602
Purity
≥98%
Packaging
100mg
Price
$477
Updated
2024/03/01
Tocris
Product number
6020
Product name
URB602
Purity
≥99%(HPLC)
Packaging
50
Price
$386
Updated
2021/12/16
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URB602 Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

URB602 is a selective inhibitor of MGL, exhibiting an IC50 of 28 for the rat brain enzyme. It does not inhibit fatty acid amide hydrolase (FAAH) at concentrations up to 100 , or other lipid metabolizing enzymes such as diacylglycerol lipase or

Uses

URB602 is a selective inhibitor of MGL, exhibiting an IC50 of 28 μM for the rat brain enzyme. It does not inhibit fatty acid amide hydrolase (FAAH) at concentrations up to 100 μM, or other lipid metabolizing enzymes such as diacylglycerol lipase or cyclooxygenase-2.5 6 Inhibition of 2-AG hydrolysis is associated with enhanced stress-induced analgesia and may represent a novel drug target in pain and stress management.

in vivo

URB602 at doses of 20 and 40 mg/kg tends to reduce upper GI transit and slow colonic propulsion. When taken together as whole gut transit, URB602 dose dependently inhibits transit (P<0.05) compared with the vehicle control group. The inhibitory action of 40 mg/kg URB602 on whole gut transit is absent in these mice, indicating CB1 receptor involvement in the inhibitory action[3]. URB602 decreases the AUC of pain behaviour during the early phase of the formalin test with an ED50 of 0.06±0.028 μg for JZL184 and 120±51.3 μg for URB602 in adult male Sprague-Dawley rats. Both MGL inhibitors also suppresses pain behaviour during the late phase of formalin pain, with an ED50 of 0.03±0.011 μg for JZL184 and 66±23.9 μg for URB602[4].

URB602 Preparation Products And Raw materials

Raw materials

Preparation Products

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URB602 Suppliers

Canada 1 China 81 India 2 United Kingdom 1 United States 13 USA 1 Global 99
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
ChemFuture PharmaTech (Jiangsu) Ltd
Tel
5108538618
Fax
86 510 85386988-8017
Email
suger.wang@chemfuture.com
Country
China
ProdList
832
Advantage
65
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
SynAsst Chemical.
Tel
021-60343070
Fax
021-35122006
Country
China
ProdList
12740
Advantage
55
Changzhou EFC Chemistry&Science Co.,Ltd
Tel
18136598690 18136597130
Fax
86-0519-89617886
Country
China
ProdList
235
Advantage
58
Shanghai Balmxy Pharmaceutical Co., Ltd
Tel
021-24206007 13764915196
Fax
86-021-23027023
Email
sales@balmxy.com
Country
China
ProdList
6874
Advantage
55
Nanjing Chalf-Pharm Technology Co., Ltd.
Tel
025-57018978 18251899859
Fax
025-57018008
Email
sales@chalf-pharm.com
Country
China
ProdList
5674
Advantage
50
AdooQ Bioscience CHINA
Tel
025-58849295 18951903616;
Fax
025-68650336
Email
info@adooq.cn
Country
China
ProdList
2990
Advantage
60
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9484
Advantage
50
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View Lastest Price from URB602 manufacturers

Career Henan Chemical Co
Product
URB602 565460-15-3
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-11

565460-15-3, URB602Related Search:

FIREMASTER BP-6 Ethoxycarbonyl Isothiocyanate Biphenyl N-Arachidonyl maleimide URB602

  • URB602
  • Biphenyl-3-yl Carbamic Acid, Cyclohexyl Ester
  • cyclohexyl biphenyl-3-ylcarbaMate
  • [1,1’-Biphenyl]-3-yl-carbamic acid cyclohexyl ester
  • Monoacylglycerol Lipase Inhibitor, URB602
  • N-[1,1'-Biphenyl]-3-yl-
  • URB 602;URB-602
  • N-[1,1'-Biphenyl]-3-yl-carbamic acid cyclohexyl ester
  • cyclohexyl N-(3-phenylphenyl)carbamate
  • Carbamic acid, N-[1,1'-biphenyl]-3-yl-, cyclohexyl ester
  • Cyclohexyl [1,1'-biphenyl]-3-ylcarbamate
  • URB602, monoglycerol lipase (MGL) inhibitor
  • URB602, 10 mM in DMSO
  • 565460-15-3
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  • Research Chemical
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  • Pharmaceutical intermediate
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