3PO
- Product Name
- 3PO
- CAS No.
- 13309-08-5
- Chemical Name
- 3PO
- Synonyms
- (E)3PO,(E) 3PO;3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one;2-Propen-1-one, 3-(3-pyridinyl)-1-(4-pyridinyl)-
- CBNumber
- CB43119750
- Molecular Formula
- C13H10N2O
- Formula Weight
- 210.23
- MOL File
- 13309-08-5.mol
3PO Property
- Melting point:
- 144-147°C
- Boiling point:
- 387.8±42.0 °C(Predicted)
- Density
- 1.192±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 4.20±0.12(Predicted)
- form
- Solid
- color
- Pale Yellow to Yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P993045
- Product name
- 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one
- Packaging
- 50mg
- Price
- $250
- Updated
- 2021/12/16
- Product number
- B4939
- Product name
- 3PO
- Packaging
- 5mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- B4939
- Product name
- 3PO
- Packaging
- 10mg
- Price
- $135
- Updated
- 2021/12/16
- Product number
- 3080CP
- Product name
- 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one
- Packaging
- 10mg
- Price
- $163
- Updated
- 2021/12/16
- Product number
- 3080CP
- Product name
- 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one
- Packaging
- 50mg
- Price
- $347
- Updated
- 2021/12/16
3PO Chemical Properties,Usage,Production
Uses
3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one inhibits human bladder cancer cell lines growth. It also inhibits cancer cell growth proliferation by it’s treatment in combination with phenoformin. An inhibitor of 6-phosphofructo-2- kinaselfructose-2,6-bisphosphatase 3 (PFKFB).
Definition
ChEBI: 3PO is a member of the class of pyridines that is pyridine substituted by a 3-oxo-3-(pyridin-4-yl)prop-1-en-1-yl group at position 3. An inhibitor of PFKFB3 kinase, an enzyme with a key role in glycolysis. It has a role as an antineoplastic agent, an angiogenesis inhibitor, an autophagy inducer, an apoptosis inducer and an EC 2.7.1.105 (6-phosphofructo-2-kinase) inhibitor. It is a member of pyridines and an enone.
storage
Store at -20°C
3PO Preparation Products And Raw materials
Raw materials
Preparation Products
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