OBIDOXIME CHLORIDE

Product Name: OBIDOXIME CHLORIDE
CAS No.: 114-90-9
Chemical Name: OBIDOXIME CHLORIDE
Synonyms: bh6;luh6;bu-6;lueh6;D009768;Obidoxim;luh(sub6);toxobidin;TOXOGONIN;Obidoxime
CBNumber: CB4312572
Molecular Formula: C14H16Cl2N4O3
Formula Weight: 359.21
MOL File: 114-90-9.mol

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OBIDOXIME CHLORIDE Property

Melting point:: 216-219oC dec.
storage temp.: -20°C Freezer
solubility: Methanol (Slightly), Water (Slightly)
color: Off-White to Light Beige
BRN: 4117377
Stability:: Stable. Incompatible with strong oxidizing agents.

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Safety

WGK Germany: 2
RTECS: UU6825000
Toxicity: LD50 in mice, rats (mg/kg): 70, 133 i.v.; 150, 225 i.p.; >2240, >4000 orally; in mice (mg/kg): 172 i.m. (Erdman, Engelhard)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 74593
Product name: Obidoxime chloride
Purity: analytical standard
Packaging: 25mg
Price: $168
Updated: 2024/03/01

Sigma-Aldrich

Product number: 51063
Product name: Obidoxime chloride
Purity: ≥95.0% (HPLC)
Packaging: 1g
Price: $407.4
Updated: 2024/03/01

TRC

Product number: O100000
Product name: Obidoxime chloride
Packaging: 10g
Price: $1295
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 29618
Product name: Obidoxime chloride
Purity: >95%
Packaging: 10g
Price: $2620
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0000731
Product name: OBIDOXIME CHLORIDE
Purity: 95.00%
Packaging: 10G
Price: $2833.1
Updated: 2021/12/16

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OBIDOXIME CHLORIDE Chemical Properties,Usage,Production

Chemical Properties

White Crystalline Solid

Originator

Toksobidin,Polfa-Starogard

Uses

antibacterial

Uses

Obidoxime Chloride is a cholinesterase reactivator.

Manufacturing Process

2 Methods of producing of obidoxime chloride: 1. Into a boiling agitated solution of 2.44 g pyridine-4-aldoxime in 10 ml absolute ethanol is added dropwise during the course of 25 min a solution of 1.14 g bis-chloromethyl ether in 5 ml absolute ethanol. The reaction mixture is then refluxed for 35 min, and then agitated for 5 h at room temperature. The precipitate of bis-[4-hydroxyimino-methyl-pyridinium-(1)-methyl]-ether Trade dichloride is thoroughly washed with absolute acetone. The yield is 3.5 g which is 98% of the theoretical, and the melting point is 229°C. If convenient, the mother liquor can be reused to make additional product.
2. 12.2 g (0.1 mole) pyridine-4-aldoxime are dissolved with heating in 125 ml chloroform. Within 25 min, 8.5 g (0.075 mole), α,α-dichlorodimethyl ether in 20 ml chloroform are dropped while stirring into the boiling solution. The reaction mixture is heated for another 35 min. After standing for several hours, the precipitate is filtered off, washed with absolute ethanol, acetone and ether and dried at 80°C. Yield: 17.0 g, 95% of the theoretical, and the melting point is 225°C (dec.).

Therapeutic Function

Antidote

General Description

active agent in Toxogonin

Biochem/physiol Actions

Antidote for organophosphate nerve agent poisoning, but, as with other oxime agents, not full spectrum. Obidoxime fails primarily to reactivate acetylcholinesterase that has been inhibited with cyclosarin.

Safety Profile

Poison by intraperitoneal,intravenous, intramuscular, and subcutaneous routes.Moderately toxic by ingestion. When heated todecomposition it emits toxic fumes of Cl- and NOx. Seealso BROMIDES.

OBIDOXIME CHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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OBIDOXIME CHLORIDE Suppliers

Canada 1 China 34 Europe 1 Germany 1 India 3 South Korea 1 Switzerland 1 United Kingdom 2 United States 7 Global 51

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View Lastest Price from OBIDOXIME CHLORIDE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: OBIDOXIME CHLORIDE 114-90-9
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-25

Dideu Industries Group Limited

Product: OBIDOXIME CHLORIDE 114-90-9
Price: US $1.10/g
Min. Order: 1g
Purity: 0.999
Supply Ability: 100 Tons min
Release date: 2021-08-13

114-90-9, OBIDOXIME CHLORIDERelated Search:

ACRYLAMIDO BUFFER Pralidoxime Chloride Bumetanide PYRIDINE-2-CARBOXALDOXIME METHIODIDE ATROPINE 0.002 MG/ML OBIDOXIME 0.15MG/M ATROPINE 2.0 MG/ML OBIDOXIME 150 MG/ML ATROPINE 0.002 MG/ML OBIDOXIME 0.15MG/M ATROPINE 0.2 MG/ML OBIDOXIME 15.0 MG/ML ATROPINE 0.2 MG/ML OBIDOXIME 15.0 MG/ML ATROPINE 2.0 MG/ML OBIDOXIME 150 MG/ML OBIDOXIME CHLORIDE OBIDOXIME FORMALDOXIME HYDROCHLORIDE 4-Pyridinealdoxime

bis(isonicotinaldoxime1-methyl)etherdichloride

bu-6

etherbis-14-hydroxy-iminomethylopyridine-(1)-metylodichloride

lueh6

luh(sub6)

luh(sub6)-cl2

luh(sup6)-cl(sup2)

luh6

luh6-chloride

luh6dichloride

n,n-dimethyleneoxidebis(pyridinium-4-aldoxime)dichloride

n,n-dimethylenoxid-bis-(pyridinium-4-aldoxim)-dichlorid

obidoximedichloride

obidoximehydrochloride

pyridinium,1,1’-(oxydimethylene)bis(4-formyl-,dichloride,dioxime

toksobidin

toxobidin

BIS(4-FORMYLPYRIDINIOMETHYL) ETHER DIOXIME

1,1'[OXYBIS(METHYLENE)]-BIS[4-(HYDROXYIMINO)METHYL]PYRIDINIUM DICHLORIDE

1,1'-(OXYDIMETHYLENE)BIS(PYRIDINIUM-4-CARBALDOXIME) DICHLORIDE

OBIDOXIME CHLORIDE

TOXOGONIN

1,1’-(oxybis(methylene))bis(4-((hydroxyimino)methyl)-pyridiniudichloride

1,1’-(oxydimethylene)bis(4-formylpyridinium)dichloridedioxime

toxogonindichloride

toxogonine

Obidoxime dihydrochloride

Obidoxime

1,3-bis(4-aldoximinopyridinium)dimethyletherbichloride

1,3-bis(4-hydroxyiminomethyl-1-pyridinio)-2-oxapropanedichloride

bh6

bis(4-hydroxyiminomethylpyridinium-1-methyl)etherdichloride

1,1’-(oxydimethylene)bis(4-formylpyridinium)dioximedichloride

1,1’-[oxybis(methylene)]bis[4-[(hydroxyimino)methyl]-pyridiniudichloride

Chloride, obidoxime

D009768

Merck brand of obidoxime chloride

Obidoxim

Pyridinium, 1,1'-(oxybis(methylene))bis(4-((hydroxyimino)methyl))-, dichloride

oxo-[[1-[[4-(oxoazaniumylmethylidene)pyridin-1-yl]methoxymethyl]pyridin-4-ylidene]methyl]azanium dichloride

OBIDOXIME CHLORIDE USP/EP/BP

1,1'-(Oxybis(methylene))bis(4-((hydroxyimino)methyl)pyridin-1-ium) chloride

Obidoxime ChlorideQ: What is Obidoxime Chloride Q: What is the CAS Number of Obidoxime Chloride Q: What is the storage condition of Obidoxime Chloride Q: What are the applications of Obidoxime Chloride

114-90-9

C14H14N4O32HCl

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