ChemicalBook > CAS DataBase List > 3-chloro-4-(6-hydroxyquinolin-2-yl)benzoic acid
3-chloro-4-(6-hydroxyquinolin-2-yl)benzoic acid
- Product Name
- 3-chloro-4-(6-hydroxyquinolin-2-yl)benzoic acid
- CAS No.
- 1371587-51-7
- Chemical Name
- 3-chloro-4-(6-hydroxyquinolin-2-yl)benzoic acid
- Synonyms
- Cavosonstat, 10 mM in DMSO;3-chloro-4-(6-hydroxyquinolin-2-yl)benzoic acid;Benzoic acid, 3-chloro-4-(6-hydroxy-2-quinolinyl)-
- CBNumber
- CB43129177
- Molecular Formula
- C16H10ClNO3
- Formula Weight
- 299.71
- MOL File
- 1371587-51-7.mol
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3-chloro-4-(6-hydroxyquinolin-2-yl)benzoic acid Property
- Boiling point:
- 527.5±50.0 °C(Predicted)
- Density
- 1.462±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- pka
- 2.70±0.10(Predicted)
- form
- Solid
- color
- Light yellow to yellow
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3-chloro-4-(6-hydroxyquinolin-2-yl)benzoic acid Chemical Properties,Usage,Production
Uses
Cavosonstat (N91115) is an orally active S-nitrosoglutathione reductase (GSNOR) inhibitor. Cavosonstat is a CFTR stabilizer, and can be used for cystic fibrosis research[1].
References
[1] Scott H Donaldson, et al. Pharmacokinetics and safety of cavosonstat (N91115) in healthy and cystic fibrosis adults homozygous for F508DEL-CFTR. J Cyst Fibros. 2017 May;16(3):371-379. DOI:10.1016/j.jcf.2017.01.009
3-chloro-4-(6-hydroxyquinolin-2-yl)benzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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3-chloro-4-(6-hydroxyquinolin-2-yl)benzoic acid Suppliers
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