IPCONAZOLE Property

Melting point:

86～92℃

Boiling point:

486.0±41.0 °C(Predicted)

Density 

1.24±0.1 g/cm3(Predicted)

vapor pressure 

3.58 x l0^-6 Pa (isomer pair I); 6.99 x l0^-6Pa (isomer pair 11) (25 °C)

Water Solubility 

6.93 mg l^-1 (20 °C)

pka

13.76±0.60(Predicted)

EPA Substance Registry System

Ipconazole (125225-28-7)

Safety

HS Code 

29339900

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H373May cause damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P314Get medical advice/attention if you feel unwell.

P330Rinse mouth.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

IPCONAZOLE Chemical Properties,Usage,Production

Uses

Ipconazole controls a wide range of seed diseases in rice and other crops and is particularly effective against 'Bakanae disease', Helminthosporum leaf spot and blast on rice.

Uses

Ipconazole is a fungicide used in pesticide compositions.

Definition

ChEBI: A member of the class of cyclopentanols carrying 1,2,4-triazol-1-ylmethyl, 4-chlorobenzyl and isopropyl substituents at positions 1, 2 and 5 respectively. Used to control a range of seed diseases in rice, vegetables and other, mainly non-food, crops.

Metabolic pathway

Ipconazole is a mixture of two geometric isomer pairs (lRS,2SR,5RS) (I) and (lRS,2SR,5SR) (Ⅱ). They differ in the orientation of the hydroxy, benzyl and isopropyl groups. The ratio of I : II in the technical product is 90 : 10 and the two-component isomer pairs are of equal activity. The metabolism of ipconazole in plants and animals involves oxidation at the benzylic and isopropyl groups to yield alcohols which may be further oxidised to the corresponding ketones or carboxylic acids (or lactones).
The resulting array of metabolites can be expected to be stereochemically more complex than the original isomer mixture.

Degradation

Ipconazole is stable towards hydrolysis and is thermally stable.