methyl 3-(hydroxymethyl)-4-nitrobenzoate
- Product Name
- methyl 3-(hydroxymethyl)-4-nitrobenzoate
- CAS No.
- 201932-92-5
- Chemical Name
- methyl 3-(hydroxymethyl)-4-nitrobenzoate
- Synonyms
- methyl 3-(hydroxymethyl)-4-nitrobenzoate;Benzoic acid, 3-(hydroxymethyl)-4-nitro-, methyl ester
- CBNumber
- CB43147311
- Molecular Formula
- C9H9NO5
- Formula Weight
- 211.17
- MOL File
- 201932-92-5.mol
methyl 3-(hydroxymethyl)-4-nitrobenzoate Property
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 8915CX
- Product name
- Methyl3-(hydroxymethyl)-4-nitrobenzoate
- Packaging
- 100mg
- Price
- $95
- Updated
- 2021/12/16
- Product number
- 8915CX
- Product name
- Methyl3-(hydroxymethyl)-4-nitrobenzoate
- Packaging
- 1g
- Price
- $220
- Updated
- 2021/12/16
- Product number
- A147033
- Product name
- Methyl3-(hydroxymethyl)-4-nitrobenzoate
- Purity
- 97%
- Packaging
- 100mg
- Price
- $20
- Updated
- 2021/12/16
- Product number
- A147033
- Product name
- Methyl3-(hydroxymethyl)-4-nitrobenzoate
- Purity
- 97%
- Packaging
- 250mg
- Price
- $39
- Updated
- 2021/12/16
- Product number
- A147033
- Product name
- Methyl3-(hydroxymethyl)-4-nitrobenzoate
- Purity
- 97%
- Packaging
- 1g
- Price
- $119
- Updated
- 2021/12/16
methyl 3-(hydroxymethyl)-4-nitrobenzoate Chemical Properties,Usage,Production
Synthesis
148625-35-8
201932-92-5
The general procedure for the synthesis of methyl 3-(hydroxymethyl)-4-nitrobenzoate from methyl 3-formyl-4-nitrobenzoate was as follows:(RS-3-49) Methyl 3-formyl-4-nitrobenzoate (1.20 g, 5.73 mmol) was dissolved in methanol (10 mL) and the solution was cooled to 0 °C. Sodium borohydride (69 mg, 1.72 mmol) was added all at once under stirring and the reaction mixture continued to be stirred at 0 °C for 20 min. Upon completion of the reaction, the reaction was quenched with 1N hydrochloric acid (10 mL) followed by evaporation under reduced pressure to remove methanol. The remaining aqueous phase was extracted with dichloromethane (3 x 10 mL) and the organic phases were combined, dried over anhydrous sodium sulfate and concentrated to afford the crude product methyl 3-(hydroxymethyl)-4-nitrobenzoate (1.06 g), which could be used in the subsequent reaction without further purification.
References
[1] Patent: WO2014/131023, 2014, A1. Location in patent: Page/Page column 138
[2] Journal of Medicinal Chemistry, 2016, vol. 59, # 10, p. 4812 - 4830
methyl 3-(hydroxymethyl)-4-nitrobenzoate Preparation Products And Raw materials
Raw materials
Preparation Products
methyl 3-(hydroxymethyl)-4-nitrobenzoate Suppliers
- Tel
- --
- Fax
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- sales@ajchem.in
- Country
- India
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View Lastest Price from methyl 3-(hydroxymethyl)-4-nitrobenzoate manufacturers
- Product
- methyl 3-(hydroxymethyl)-4-nitrobenzoate 201932-92-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-10