(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochloride

Product Name: (R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochloride
CAS No.: 1428118-39-1
Chemical Name: (R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochloride
Synonyms: Cinacalcet-16;Cinacalcet USP RC C;Cinacalcene Impurity G;Cinacalcet Related Compound C;Cinacalcet USP Related Compound C;Cinacalcet Impurity 2(Cinacalcet USP RC C);Cinacalcet Related Compound C United States Pharmacopeia (USP) Reference Standard;(R)-N-(1-(phthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-aminehydrochloride;(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochloride;(αR)-α-Methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine Hydrochoride Salt
CBNumber: CB43154777
Molecular Formula: C22H23ClF3N
Formula Weight: 393.88
MOL File: 1428118-39-1.mol

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(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochloride Property

solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
color: Pale Beige
Major Application: pharmaceutical (small molecule)
InChI: InChI=1/C22H22F3N.ClH/c1-16(20-10-4-8-18-7-2-3-9-21(18)20)26-15-5-6-17-11-13-19(14-12-17)22(23,24)25;/h2-4,7-14,16,26H,5-6,15H2,1H3;1H/t16-;/s3
InChIKey: DSKNQUVQQYTQFT-LSQUZMQTNA-N
SMILES: [C@H](C1=CC=CC2C=CC=CC1=2)(C)NCCCC1C=CC(C(F)(F)F)=CC=1.Cl |&1:0,r|

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Safety

WGK Germany: WGK 3
HS Code: 2921490002
Storage Class: 10 - Combustible liquids
Hazard Classifications: Aquatic Chronic 4
Eye Dam. 1
Skin Sens. 1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H317May cause an allergic skin reaction

H318Causes serious eye damage

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochloride Chemical Properties,Usage,Production

Uses

(aR)-a-Methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine Hydrochloride, is an impurity of Cinacalcet (C441800), which is a drug that acts as a calcimimetic, and is used to treat secondary hyperparathyroidism (elevated parathyroid hormone levels).

(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochloride Suppliers

China 41 India 3 United States 2 Global 46

Wuhan Yanzhe Technology Co., Ltd

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Standardpharm Co. Ltd.

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1428118-39-1, (R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochlorideRelated Search:

1-(1-NAPHTHYL)ETHANOL Methanesulfonic acid 3-(3-trifluoroMethylphenyl)propyl ester (S)-(-)-1-(1-Naphthyl)ethylamine Methyl 3-(3-(trifluoroMethyl)phenyl)propanoate 1-NaphthaleneMethanaMine, 7,8-dihydro-α-Methyl-N-[3-[3-(trifluoroMethyl)phenyl]propyl]-, hydrochloride (1:1), (αR)- (R)-(+)-1-(1-Naphthyl)ethylamine N-(1-(5,6,7,8-tetrahydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propanamide N-((R)-1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoroMethyl)phenyl)propanaMide 1-(7,8-dihydronaphthalen-1-yl)ethan-1-amine hydrochloride Cinacalcet IMpurity 7 1'-Acetonaphthone Cinacalcet 7,8-Dihydro Racemate HCl 3-[o-(alpha,alpha,alpha-trifluorotolyl)]propionic acid (αR)-α-Methyl-N-[3-[3-(trifluoroMethyl)phenyl)propyl]-1-napthaleneMethanaMine-N-oxide cinacalcet iMpurity 4 1-(5,6,7,8-tetrahydronaphthalen-1-yl)ethan-1-amine hydrochloride (R)-1-(5,6-dihydronaphthalen-1-yl)ethan-1-amine 3-(3-Trifluoromethylphenyl)propionic acid

Cinacalcet Impurity 2(Cinacalcet USP RC C)

Cinacalcet impurity 17/(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochloride

Cinacalcet-16

(R)-N-(1-(phthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-aminehydrochloride

(E)-N-(1-(7,8-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)acrylamide hydrochloride

Cinacalcet USP RC C

1-Naphthalenemethanamine, α-methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-, hydrochloride (1:1), (αR)

Cinacalcet USP Related Compound C

(αR)-α-Methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethan amine Hydrochoride Salt

Cinacalcene Impurity G

Cinacalcet Related Compound C United States Pharmacopeia (USP) Reference Standard

(αR)-α-Methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine Hydrochoride Salt

Cinacalcet para isomer-(3-(4-(trifluoromethyl)phenyl)-N-((R)-1-(naphthalen-5-yl)ethyl)propan-1-amine or (R)-N-(1-(Naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl) phenyl)propan-1-amine)

(alphaR)-alpha-Methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine Hydrochloride Salt

(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochloride

Cinacalcet Related Compound C

1428118-39-1