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Fezolinetant

Product Name
Fezolinetant
CAS No.
1629229-37-3
Chemical Name
Fezolinetant
Synonyms
ESN-364;Fexolinetant;FEZOLINETANT; ESN-364; ESN 364; ESN364;Inhibitor,Neurokinin Receptor,ESN364,Tachykinin receptor,ESN 364,Fezolinetant,inhibit,NK receptor;(R)-(4-fluorophenyl)(8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone;Methanone, [(8R)-5,6-dihydro-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl](4-fluorophenyl)-
CBNumber
CB43159873
Molecular Formula
C16H15FN6OS
Formula Weight
358.39
MOL File
1629229-37-3.mol
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Fezolinetant Property

Boiling point:
623.0±65.0 °C(Predicted)
Density 
1.56±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:20.0(Max Conc. mg/mL);55.8(Max Conc. mM)
pka
-0.28±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-7952
Product name
Fezolinetant
Purity
98.16%
Packaging
1mg
Price
$120
Updated
2021/12/16
ChemScene
Product number
CS-7952
Product name
Fezolinetant
Purity
98.16%
Packaging
5mg
Price
$390
Updated
2021/12/16
ChemScene
Product number
CS-7952
Product name
Fezolinetant
Purity
98.16%
Packaging
10mg
Price
$570
Updated
2021/12/16
ChemScene
Product number
CS-7952
Product name
Fezolinetant
Purity
98.16%
Packaging
25mg
Price
$1140
Updated
2021/12/16
ChemScene
Product number
CS-7952
Product name
Fezolinetant
Purity
98.16%
Packaging
50mg
Price
$1740
Updated
2021/12/16
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Fezolinetant Chemical Properties,Usage,Production

Uses

Fezolinetant is an antagonist of the neurokinin 3 receptor (NK3R), used for the treatment of menopausal hot flushes.

Definition

ChEBI: Fezolinetant is a triazolopyrazine that is 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine substituted by 3-methyl-1,2,4-thiadiazol-5-yl, 4-fluorobenzoyl and methyl groups at positions 3, 7, and 8R, respectively. It is a prescription medicine used to reduce moderate to severe vasomotor symptoms due to menopause. It has a role as a neurokinin-3 receptor antagonist. It is a member of monofluorobenzenes, a triazolopyrazine, a member of thiadiazoles, a member of benzamides and a tertiary carboxamide.

Fezolinetant Preparation Products And Raw materials

Raw materials

Preparation Products

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Fezolinetant Suppliers

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View Lastest Price from Fezolinetant manufacturers

Jinan Million Pharmaceutical Co., Ltd
Product
Birinapant 1629229-37-3
Price
US $1.00-0.50/kg
Min. Order
1kg
Purity
99%
Supply Ability
200
Release date
2024-03-21

1629229-37-3, FezolinetantRelated Search:


  • FEZOLINETANT; ESN-364; ESN 364; ESN364
  • ESN-364
  • Methanone, [(8R)-5,6-dihydro-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl](4-fluorophenyl)-
  • Inhibitor,Neurokinin Receptor,ESN364,Tachykinin receptor,ESN 364,Fezolinetant,inhibit,NK receptor
  • (R)-(4-fluorophenyl)(8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone
  • Fexolinetant
  • 1629229-37-3
  • APIS
  • API