ChemicalBook > CAS DataBase List > 4-amino-7-iodopyrrolo [2,1-f ] [1,2,4] triazine

4-amino-7-iodopyrrolo [2,1-f ] [1,2,4] triazine

Product Name
4-amino-7-iodopyrrolo [2,1-f ] [1,2,4] triazine
CAS No.
1770840-43-1
Chemical Name
4-amino-7-iodopyrrolo [2,1-f ] [1,2,4] triazine
Synonyms
SKL530;Remdesivir-004;Starting material);4-Amino-7-iodopyrroL;Redesivir Impurity 3;Remdesivir Impurity 20;o[2,1-f][1,2,4]triazine;Remdesivir N-6 iodotriazine;7-iodopyrrolo[2,1-f][1,2,4]triazin-4-;7-iodopyrrole[2,1-f][1,2,4]triazin-4-amine
CBNumber
CB43166572
Molecular Formula
C6H5IN4
Formula Weight
260.04
MOL File
1770840-43-1.mol
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4-amino-7-iodopyrrolo [2,1-f ] [1,2,4] triazine Property

Density 
2.43±0.1 g/cm3(Predicted)
pka
3.04±0.30(Predicted)
form 
solid
color 
Pale yellow
InChI
InChI=1S/C6H5IN4/c7-5-2-1-4-6(8)9-3-10-11(4)5/h1-3H,(H2,8,9,10)
InChIKey
ZEBGLCLVPCOXIV-UHFFFAOYSA-N
SMILES
N12C(I)=CC=C1C(N)=NC=N2
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
I1139
Product name
7-Iodopyrrolo[2,1-f][1,2,4]triazin-4-amine
Packaging
1G
Price
$87
Updated
2025/07/31
TCI Chemical
Product number
I1139
Product name
7-Iodopyrrolo[2,1-f][1,2,4]triazin-4-amine
Packaging
5G
Price
$263
Updated
2025/07/31
AK Scientific
Product number
3155EB
Product name
4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine
Packaging
250mg
Price
$323
Updated
2021/12/16
SynQuest Laboratories
Product number
3H30-H-0K
Product name
7-Iodopyrrolo[2,1-f][1,2,4]triazin-4-amine
Purity
97%
Packaging
25g
Price
$336
Updated
2021/12/16
AK Scientific
Product number
3155EB
Product name
4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine
Packaging
1g
Price
$458
Updated
2021/12/16
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4-amino-7-iodopyrrolo [2,1-f ] [1,2,4] triazine Chemical Properties,Usage,Production

Uses

4-amino-7-iodopyrrolo[2,1-f][1,2,4]triazine is an amine organic substance and can be used as an intermediate for APIs.

Uses

7-Iodopyrrolo[2,1-f][1,2,4]triazin-4-amine is a useful reagent in the synthesis of phosphoramidate GS-5734 prodrug for potential treatment of Ebola virus infections and in the preparation of Remdesivir as COVID-19 antiviral drug candidate.

Synthesis

The synthesis reaction of 4-amino-7-iodopyrrolo [2,1-f ] [1,2,4] triazine is as follows: 4-amino pyrrolo [2,1-f ] [1,2,4] triazine reacts with iodine or iodine chloride under mild conditions to generate most of iodinated products, isomers and diiodized products are not generated under the mild conditions, and unreacted materials react with N-iodosuccinimide to further ensure that raw materials completely react, so that the conversion rate of the raw materials is improved, and the generation of the isomer products and the diiodized products is also inhibited.

4-amino-7-iodopyrrolo [2,1-f ] [1,2,4] triazine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-amino-7-iodopyrrolo [2,1-f ] [1,2,4] triazine Suppliers

Chengdu Aslee Biopharmaceuticals, Inc
Tel
028-85305008 02885305008
Fax
4000210878-186
Email
2306208234@qq.com
Country
China
ProdList
1006
Advantage
50
LinkChem Technology Co., Ltd.
Tel
021-58950110 13124863828
Fax
021-20922272
Email
sales@linkchem.cn
Country
China
ProdList
3000
Advantage
58
Shanghai Synmedia Chemical Co., Ltd.
Tel
021-38681880 13817889927
Fax
0213390-8196
Email
sales@synmedia-chem.com
Country
China
ProdList
249
Advantage
58
Henan yu Chen pharmaceutical co., LTD
Tel
0374-5699939 18864655557
Fax
+86-374-5699958
Email
yuchenchem@126.com
Country
China
ProdList
30
Advantage
58
Bellen Chemistry Co., Ltd.
Tel
010-60400365-8001 15910885229
Fax
010-60400361
Email
service@bellenchem.com
Country
China
ProdList
4514
Advantage
60
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44802
Advantage
61
Nanjing Habo Medical Technology Co., Ltd.
Tel
025-85760892 13376080562
Fax
025-85766769
Email
sales@habotech.com
Country
China
ProdList
890
Advantage
60
ChengDu TongChuangYuan Pharmaceutical Co.Ltd
Tel
28-83379370 13880556291
Fax
028-87747383
Email
tcy@tcypharm.com
Country
China
ProdList
510
Advantage
57
Puyang Huicheng Electronic Material Co. Ltd.
Tel
0393-8910800 18339358320
Fax
0393-8912775
Email
info@huichengchem.com
Country
China
ProdList
568
Advantage
64
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11032
Advantage
64
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View Lastest Price from 4-amino-7-iodopyrrolo [2,1-f ] [1,2,4] triazine manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
7-Iodopyrrolo[2,1-f][1,2,4]triazin-4-amine 1770840-43-1
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kgs
Release date
2025-09-25
Jinan Finer Chemical Co., Ltd
Product
7-iodopyrrolo[2,1-f][1,2,4]triazin-4-amine 1770840-43-1
Price
US $0.00/Kg/Drum
Min. Order
1g
Purity
99%
Supply Ability
20mt
Release date
2020-03-31
Hebei Chuanghai Biotechnology Co., Ltd
Product
4-amino-7-iodopyrrolo[2,1-f][1,2,4]triazine 1770840-43-1
Price
US $30.00-10.00/KG
Min. Order
50KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-24

1770840-43-1, 4-amino-7-iodopyrrolo [2,1-f ] [1,2,4] triazineRelated Search:


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