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Phenyl dichlorophosphate

Product Name
Phenyl dichlorophosphate
CAS No.
770-12-7
Chemical Name
Phenyl dichlorophosphate
Synonyms
PHENYL PHOSPHORODICHLORIDATE;MPCP;O-phenyl phosphorodichloridate;PCDP;orophosphate;Phenyl dichlorophosp;Picaridin Impurity 7;Phenyl dichlorophosphat;PHENYL DICHLOROPHOSPHATE;PHYENYL DICHLOVOPHOSPHATE
CBNumber
CB1669062
Molecular Formula
C6H5Cl2O2P
Formula Weight
210.98
MOL File
770-12-7.mol
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Phenyl dichlorophosphate Property

Melting point:
-1 °C
Boiling point:
241-243 °C (lit.)
Density 
1.412 g/mL at 25 °C (lit.)
vapor pressure 
2.33Pa at 25℃
refractive index 
n20/D 1.523(lit.)
Flash point:
>230 °F
storage temp. 
2-8°C
solubility 
soluble in Chloroform
form 
Liquid
color 
Clear colorless to very slightly brown
Water Solubility 
Decomposes
Sensitive 
Moisture Sensitive
Merck 
14,7282
BRN 
511863
Stability:
Moisture Sensitive
InChIKey
TXFOLHZMICYNRM-UHFFFAOYSA-N
CAS DataBase Reference
770-12-7(CAS DataBase Reference)
NIST Chemistry Reference
Phosphorodichloridic acid, phenyl ester(770-12-7)
EPA Substance Registry System
Phosphorodichloridic acid, phenyl ester (770-12-7)
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Safety

Hazard Codes 
C
Risk Statements 
34-37
Safety Statements 
26-36/37/39-45
RIDADR 
UN 3265 8/PG 2
WGK Germany 
3
RTECS 
TD4393000
10
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
29209085
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P22389
Product name
Phenyl dichlorophosphate
Purity
≥95%
Packaging
100g
Price
$50.4
Updated
2024/03/01
Sigma-Aldrich
Product number
P22389
Product name
Phenyl dichlorophosphate
Purity
≥95%
Packaging
25g
Price
$59
Updated
2024/03/01
TCI Chemical
Product number
P0209
Product name
Phenyl Dichlorophosphate
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$22
Updated
2024/03/01
TCI Chemical
Product number
P0209
Product name
Phenyl Dichlorophosphate
Purity
>98.0%(GC)(T)
Packaging
500g
Price
$300
Updated
2024/03/01
Alfa Aesar
Product number
A10479
Product name
Phenyl phosphorodichloridate, 97%
Packaging
25g
Price
$26.65
Updated
2024/03/01
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Phenyl dichlorophosphate Chemical Properties,Usage,Production

Chemical Properties

clear colourless to very slightly brown liquid

Uses

Reagent for the preparation of phosphate diesters.

Uses

Reagent for preparation of phosphate diesters. Phenyl dichlorophosphate is used in the preparation of symmetrical phosphate diesters. It is used as a phosphorylating agent for alcohols and amines. It is also involved in the preparation of phenylphosphoro di-(1-imidazolidate) and 2-phenyl-bis-triazoloylphosphate, which is used in peptide synthesis. It plays a vital role in the Pfitzner-Moffatt oxidation which involves oxidation of alcohols to the corresponding aldehydes and ketones. Furthermore, it is utilized in Beckmann rearrangement for the preparation of N-phenylacetamide from acetophenone oxime.

Uses

In organic synthesis for preparation of lactams, phosphate diesters and for oxidation reactions.

Preparation

The preparation of Phenyl dichlorophosphate is as follows:160 g (1 mol) of phosphorus oxychloride and 1 g of titanium tetrachloride were respectively added to a four-necked flask to carry out the reaction, and the temperature was raised to 70-80° C., and phenol (94 g, 1 mol) was slowly added dropwise. The phenol addition time was about 2- 3 hours,After completion of the dropwise addition, the reaction is maintained at 80-90° C. for 3-5 hours. After no hydrogen chloride is evolved, the reaction is completed. After the reaction, the phosphorus oxychloride is distilled under reduced pressure, the vacuum degree is 30-100 KPa, and the distillation temperature is 30-100° C. Distillation under reduced pressure to obtain the intermediate of the mixture, a mono-substituted and di-substituted mixture of phosphorus oxychloride, the ratio of the mixture is 5:5, gas phase analysis to obtain the intermediate of the mixture, the yield of the intermediate is 95%, phosphorus oxychloride The recovery rate is 95% (calculated as phosphorus oxychloride).

General Description

A liquid. May severely irritate skin, eyes and mucous membranes.

Air & Water Reactions

About the same density as water and moderately soluble in water.

Reactivity Profile

An hologenated organophosphate. Organophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Hazard

May cause severe skin, eye, and mucous membrane irritation; Reacts violently with water; Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; Toxic by ingestion; Highly toxic by skin absorption; Dermal LD50 (guinea pig) = 14-400 mg/kg.

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.

Phenyl dichlorophosphate Preparation Products And Raw materials

Raw materials

Preparation Products

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Phenyl dichlorophosphate Suppliers

Changzhou Huasheng Chemical Technology Co., Ltd
Tel
0519-85861892 13861049519
Email
1187729375@qq.com
Country
China
ProdList
55
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Taizhou zhenhe chemical co. LTD
Tel
576-88887792 13386577269
Fax
0576-88931773
Email
sales@zhenhechemical.com
Country
China
ProdList
114
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58
Jinan Tai Hang Seng Material Technology Co., LTD
Tel
17852565707
Email
157163860@qq.com
Country
China
ProdList
14
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58
HEZE DIJADE CHEMCAL CORPORATION
Tel
0530-7157019 18678572026
Email
3109950577@qq.com
Country
China
ProdList
18
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58
Dongyang Qiusuo Medical Technology Co., LTD
Tel
17502510579
Email
2785299132@qq.com
Country
China
ProdList
1558
Advantage
58
Nanjing Yihua Biotechnology Co., Ltd
Tel
15952064210
Email
184982398@qq.com
Country
China
ProdList
296
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58
Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2208
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
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View Lastest Price from Phenyl dichlorophosphate manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Phenyl dichlorophosphate 770-12-7
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 mt
Release date
2024-11-20
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Phenyl Dichlorophosphate 770-12-7
Price
US $65.00-20.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-31
Hebei Chuanghai Biotechnology Co,.LTD
Product
Phenyl Dichlorophosphate 770-12-7
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-19

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