TLR2-IN-C29

Product Name: TLR2-IN-C29
CAS No.: 363600-92-4
Chemical Name: TLR2-IN-C29
Synonyms: R2-IN-C29;TLR2-IN-C29;C29;C 29;C-29;C29, 10 mM in DMSO;TLR2-IN-C29 (C29 );3-((2-Hydroxy-3-methoxybenzylidene)amino)-2-methylbenzoic acid;Benzoic acid, 3-[[(2-hydroxy-3-methoxyphenyl)methylene]amino]-2-methyl-;C29,TLR2,Inhibitor,hTLR2/1,inhibit,C-29,Toll-like,Toll-like Receptor (TLR),hTLR2/6,C 29
CBNumber: CB43168697
Molecular Formula: C16H15NO4
Formula Weight: 285.29
MOL File: 363600-92-4.mol

More

Less

TLR2-IN-C29 Property

Melting point:: >192°C (dec.)
Boiling point:: 505.7±50.0 °C(Predicted)
Density: 1.21±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 4.01±0.10(Predicted)
color: Dark Orange
Stability:: Moisture Sensitive

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 27029
Product name: C29
Packaging: 1mg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 27029
Product name: C29
Packaging: 25mg
Price: $745
Updated: 2024/03/01

Cayman Chemical

Product number: 27029
Product name: C29
Packaging: 5mg
Price: $194
Updated: 2024/03/01

Cayman Chemical

Product number: 27029
Product name: C29
Packaging: 10mg
Price: $357
Updated: 2024/03/01

TRC

Product number: T426518
Product name: TLR2-IN-C29
Packaging: 2.5mg
Price: $150
Updated: 2021/12/16

More

Less

TLR2-IN-C29 Chemical Properties,Usage,Production

Uses

TLR2-IN-29 is a inhibitor of TLR2/1 and TLR2/6 signaling induced by synthetic and bacterial TLR2 agonists in human HEK-TLR2 and THP-1 cells, but only TLR2/1 signaling in murine macrophages.

Biological Activity

TLR2-IN-C29 is a toll/IL-1 receptor resistance (TIR) domain BB loop-targeting, selective toll-like receptor 2 (TLR2) antagonist th at inhibits both human TLR2/1 and TLR2/6-mediated signaling (IC50 = 37.6/19.7 μM against 50 ng/mL Pam3CSK/Pam2CSK-induced reporter signal, respectively, using HEK293T TLR2/6 or TLR2/1 transfectants), while blocking only murine TLR2/1-, but not murine TLR2/6-, mediated signaling (1h 25-50 μM C29 treatment prior to 50 ng P3C/mL or 100 ng P2C/mL for 1h in murine macrophages), nor signaling induced by other TLR agonists and TNF-α.

TLR2-IN-C29 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

TLR2-IN-C29 Suppliers

China 69 India 1 United States 8 USA 1 Global 79

Shandong Jirun Biomedical Technology Co., Ltd.

Tel: 0539-0539-8613587 17661611089
Fax: qq2639273505
Email: 2639273505@qq.com
Country: China
ProdList: 174
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66099280 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19915
Advantage: 55

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 16166
Advantage: 55

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4573
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 27313
Advantage: 60

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
ProdList: 5944
Advantage: 55

ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 4009686088
Email: 3193328036@qq.com
Country: China
ProdList: 29764
Advantage: 68

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

More

Less

View Lastest Price from TLR2-IN-C29 manufacturers

Career Henan Chemical Co

Product: TLR2-IN-C29 363600-92-4
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 20kg
Release date: 2019-12-23

363600-92-4, TLR2-IN-C29Related Search:

C29;C 29;C-29

TLR2-IN-C29

R2-IN-C29

Benzoic acid, 3-[[(2-hydroxy-3-methoxyphenyl)methylene]amino]-2-methyl-

3-((2-Hydroxy-3-methoxybenzylidene)amino)-2-methylbenzoic acid

TLR2-IN-C29 (C29 )

C29,TLR2,Inhibitor,hTLR2/1,inhibit,C-29,Toll-like,Toll-like Receptor (TLR),hTLR2/6,C 29

C29, 10 mM in DMSO

363600-92-4