Peptide 46

Product Name: Peptide 46
CAS No.: 192122-40-0
Chemical Name: Peptide 46
Synonyms: PEPTIDE 46;P53 (361-382) (HUMAN);CELLULAR TUMOR ANTIGEN P53 (361-382) (HUMAN);p53 (361-382) (huMan), Cellular TuMor Antigen p53 (361-382) (huMan);H-GLY-SER-ARG-ALA-HIS-SER-SER-HIS-LEU-LYS-SER-LYS-LYS-GLY-GLN-SER-THR-SER-ARG-HIS-LYS-LYS-OH;Glycyl-L-seryl-L-arginyl-L-alanyl-L-histidyl-L-seryl-L-seryl-L-histidyl-L-leucyl-L-lysyl-L-seryl-L-lysyl-L-lysylglycyl-L-glutaminyl-L-seryl-L-threonyl-L-seryl-L-arginyl-L-histidyl-L-lysyl-L-lysine;L-Lysine, glycyl-L-seryl-L-arginyl-L-alanyl-L-histidyl-L-seryl-L-seryl-L-histidyl-L-leucyl-L-lysyl-L-seryl-L-lysyl-L-lysylglycyl-L-glutaminyl-L-seryl-L-threonyl-L-seryl-L-arginyl-L-histidyl-L-lysyl-
CBNumber: CB4323244
Molecular Formula: C100H174N40O31
Formula Weight: 2432.7
MOL File: 192122-40-0.mol

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Peptide 46 Property

Density: 1.56±0.1 g/cm3(Predicted)
storage temp.: -15°C
InChIKey: KCXVFJXIDLDWKX-JEWKGGOJSA-N

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: ATG0000935
Product name: CELLULAR TUMOR ANTIGEN P53 (361-382) (HUMAN)
Purity: 95.00%
Packaging: 5MG
Price: $496.31
Updated: 2021/12/16

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Peptide 46 Chemical Properties,Usage,Production

Description

Peptide 46, a synthetic 22-mer peptide derived from the p53 C-terminal domain, can restore the growth suppressor function of mutant p53 proteins in human tumor cells. The sequence of peptide 46, which corresponds to residues 361 to 382 in the p53 C terminus, is (in one-letter code) GSRAHSSHLKSKKGQSTSRHKK[1]. Teptide 46, the only C-terminal peptide that can activate the specific DNA binding of p53, changed the mobility of the core domain, whereas the other C-terminal peptides did not. Conversely, the mobility of the C-terminal domain protein was shifted upon incubation with the core domain protein.

References

[1] G Selivanova. “Reactivation of mutant p53 through interaction of a C-terminal peptide with the core domain.” Molecular and Cellular Biology 19 5 (1999): 3395–402.

Peptide 46 Preparation Products And Raw materials

Raw materials

Preparation Products

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Peptide 46 Suppliers

China 27 United States 2 Global 29

Creative Peptides

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Email: info@creative-peptides.com
Country: United States
ProdList: 6083
Advantage: 56

Chem-Impex International, Inc.

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Country: United States
ProdList: 6730
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View Lastest Price from Peptide 46 manufacturers

Wuhan Xinhao Biotechnology Co., Ltd

Product: PEPTIDE 46 192122-40-0
Price: US $2.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 200kg
Release date: 2024-01-11

192122-40-0, Peptide 46Related Search:

Peptide 46

PEPTIDE 46

P53 (361-382) (HUMAN)

p53 (361-382) (huMan), Cellular TuMor Antigen p53 (361-382) (huMan)

H-GLY-SER-ARG-ALA-HIS-SER-SER-HIS-LEU-LYS-SER-LYS-LYS-GLY-GLN-SER-THR-SER-ARG-HIS-LYS-LYS-OH

CELLULAR TUMOR ANTIGEN P53 (361-382) (HUMAN)

Glycyl-L-seryl-L-arginyl-L-alanyl-L-histidyl-L-seryl-L-seryl-L-histidyl-L-leucyl-L-lysyl-L-seryl-L-lysyl-L-lysylglycyl-L-glutaminyl-L-seryl-L-threonyl-L-seryl-L-arginyl-L-histidyl-L-lysyl-L-lysine

L-Lysine, glycyl-L-seryl-L-arginyl-L-alanyl-L-histidyl-L-seryl-L-seryl-L-histidyl-L-leucyl-L-lysyl-L-seryl-L-lysyl-L-lysylglycyl-L-glutaminyl-L-seryl-L-threonyl-L-seryl-L-arginyl-L-histidyl-L-lysyl-

192122-40-0