6-Methoxy-2-tetralone
- Product Name
- 6-Methoxy-2-tetralone
- CAS No.
- 2472-22-2
- Chemical Name
- 6-Methoxy-2-tetralone
- Synonyms
- 6-methoxy-2-Tetrlone;4-dihydro-6-Methoxy-;6-METHOXY-2-TETRALONE;6-methoxyl-2-tetralone;6-Methoxytetralin-2-one;6-Methoxy-2-tetralone>6-METHOXY-2-TETRALONE 95%;6-Methoxy-2-tetralone,98%;6-Methoxy-2-tetralone,90%;6-Methoxy-2-tetralone,tech.90%
- CBNumber
- CB4323880
- Molecular Formula
- C11H12O2
- Formula Weight
- 176.21
- MOL File
- 2472-22-2.mol
6-Methoxy-2-tetralone Property
- Melting point:
- 28-35 °C
- Boiling point:
- 114-116 °C (0.2 mmHg)
- Density
- 1.0431 (rough estimate)
- refractive index
- n20/D 1.5645(lit.)
- Flash point:
- >230 °F
- storage temp.
- 2-8°C
- form
- Crystalline Low Melting Solid
- color
- Light yellow-beige to orange
- Sensitive
- Air Sensitive
- BRN
- 513418
- InChI
- InChI=1S/C11H12O2/c1-13-11-5-3-8-6-10(12)4-2-9(8)7-11/h3,5,7H,2,4,6H2,1H3
- InChIKey
- RMRKDYNVZWKAFP-UHFFFAOYSA-N
- SMILES
- C1C2=C(C=C(OC)C=C2)CCC1=O
- CAS DataBase Reference
- 2472-22-2(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P233Keep container tightly closed.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304IF INHALED:
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P340Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362Take off contaminated clothing and wash before reuse.
P403Store in a well-ventilated place.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 184063
- Product name
- 6-Methoxy-3,4-dihydro-2(1H)-naphthalenone
- Purity
- 95%
- Packaging
- 1g
- Price
- $66.2
- Updated
- 2024/03/01
- Product number
- 184063
- Product name
- 6-Methoxy-3,4-dihydro-2(1H)-naphthalenone
- Purity
- 95%
- Packaging
- 5g
- Price
- $314
- Updated
- 2024/03/01
- Product number
- M1317
- Product name
- 6-Methoxy-2-tetralone
- Purity
- >95.0%(GC)
- Packaging
- 1g
- Price
- $81
- Updated
- 2024/03/01
- Product number
- M1317
- Product name
- 6-Methoxy-2-tetralone
- Purity
- >95.0%(GC)
- Packaging
- 5g
- Price
- $395
- Updated
- 2021/12/16
- Product number
- L11007
- Product name
- 6-Methoxy-2-tetralone, tech. 90%
- Packaging
- 1g
- Price
- $100
- Updated
- 2021/12/16
6-Methoxy-2-tetralone Chemical Properties,Usage,Production
Description
6-methoxy-2-tetralone has been selected as the starting material for the synthesis of many steroidal compounds, including 2-aminotetalin derivatives, which exhibit antifungal activities, tetrahydro benzocycloheptane and many terpenoid compounds. 6-methoxy-2-tetralone is more expensive, difficult to synthesize, and unstable in comparison to 6-methoxy-1-tetralone[1].
Chemical Properties
light yellow-beige to orange
Uses
6-Methoxy-3,4-dihydro-2(1H)-naphthalenone was used in the synthesis of 1, 2, 3, 4-tetrahydro-2-naphthylamine derivatives.
Synthesis Reference(s)
Chemical and Pharmaceutical Bulletin, 9, p. 267, 1961 DOI: 10.1248/cpb.9.267
The Journal of Organic Chemistry, 26, p. 3237, 1961 DOI: 10.1021/jo01067a049
Synthesis
To a suspension of MCPBA (1.5g, 8.7mmol) in dry dichloromethane (16mL), cooled in ice, was added dihydro naphthalene (616mg, 3.8mmol) dissolved in dichloromethane (2mL). The reaction mixture was stirred overnight, filtered, diluted with dichloromethane, washed with a solution of sodium bicarbonate (5%), brine, dried, and evaporated to obtain an oil (591mg), which without purification was dissolved in ethanol (3mL) and treated with sulfuric acid (3mL, 10%) and heated under reflux for 3 hours. The reaction mixture was cooled, diluted with water, and extracted three times using chloroform. The organic extracts were washed with brine, dried, and evaporated to obtain an oil which, on purification (eluent hexane: ether 7:3), afforded 6-Methoxy-2-tetralone.
References
[1] Banerjee, A. K. et al. “A concise approach for the synthesis of 6-methoxy-2-tetralone.” 2018. 0.
6-Methoxy-2-tetralone Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-Methoxy-2-tetralone manufacturers
- Product
- 6-Methoxy-2-tetralone 2472-22-2
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-06-04
- Product
- 6-Methoxy-2-tetralone 2472-22-2
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 2-5 MTs
- Release date
- 2024-05-11
- Product
- 6-Methoxy-2-tetralone 2472-22-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2023-05-29