PROSTAGLANDINS F2ALPHA METHYL ESTER

Product Name: PROSTAGLANDINS F2ALPHA METHYL ESTER
CAS No.: 33854-16-9
Chemical Name: PROSTAGLANDINS F2ALPHA METHYL ESTER
Synonyms: PGF2a methyl;13e,15s)-alph;PGF2ALPHA-OME;pgf2methylester;Dinoprost methyl;dinoprostmethylester;pgf2-alphamethylester;Carboprost Impurity 9;prostaglandinf2methylester;PJDMFGSFLLCCAO-NVRZHKMMSA-N
CBNumber: CB4329589
Molecular Formula: C21H36O5
Formula Weight: 368.51
MOL File: 33854-16-9.mol

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PROSTAGLANDINS F2ALPHA METHYL ESTER Property

Boiling point:: 418.83°C (rough estimate)
Density: 1.0390 (rough estimate)
refractive index: 1.6120 (estimate)
Flash point:: -9 °C
storage temp.: −20°C
solubility: DMF: 35 mg/ml; DMSO: 35 mg/ml; Ethanol: 50 mg/ml; Ethanol:PBS (pH 7.2) (1:4): 0.4 mg/ml

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Safety

Hazard Codes: F,Xi
Risk Statements: 11-36-66-67
Safety Statements: 16-26-29-33
RIDADR: UN 1231 3/PG 2
WGK Germany: 1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

H336May cause drowsiness or dizziness

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P0314
Product name: Prostaglandin F2α methyl ester
Purity: ~5 mg/mL in methyl acetate, ≥95% (HPLC)
Packaging: 1mg
Price: $315
Updated: 2022/05/15

Cayman Chemical

Product number: 16011
Product name: Prostaglandin F2α methyl ester
Purity: ≥98%
Packaging: 500μg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 16011
Product name: Prostaglandin F2α methyl ester
Purity: ≥98%
Packaging: 1mg
Price: $61
Updated: 2024/03/01

Cayman Chemical

Product number: 16011
Product name: Prostaglandin F2α methyl ester
Purity: ≥98%
Packaging: 5mg
Price: $243
Updated: 2024/03/01

Cayman Chemical

Product number: 16011
Product name: Prostaglandin F2α methyl ester
Purity: ≥98%
Packaging: 10mg
Price: $426
Updated: 2024/03/01

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PROSTAGLANDINS F2ALPHA METHYL ESTER Chemical Properties,Usage,Production

Uses

Prostaglandin F2α methyl ester (PGF2α methyl ester; Dinoprost methyl) is a PGF2α analog with more lipid solubility. Prostaglandin F2α methyl ester exhibits efficacy in maintaining the ocular hypotensive[1].

Definition

ChEBI: PGF2alpha methyl ester is a prostanoid.

Biochem/physiol Actions

Constricts an isolated human smooth muscle; methyl ester form of prostaglandin F2α which is a luteolytic prostaglandin (induces parturition; pulmonary vasoconstrictor).

in vivo

Prostaglandin F2α methyl ester (1-10 μg for one eye, single dose) lowers the intraocular pressure (IOP) and reduces pupillary diameter in cats^[1].

Animal Model:	Cats^[1]
Dosage:	1-10 μg
Administration:	topically applied for one eye
Result:	lowered the IOP and reduced pupillary diameter.

References

[1] Bito LZ. Comparison of the ocular hypotensive efficacy of eicosanoids and related compounds. Exp Eye Res. 1984 Feb;38(2):181-94. DOI:10.1016/0014-4835(84)90102-7

PROSTAGLANDINS F2ALPHA METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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PROSTAGLANDINS F2ALPHA METHYL ESTER Suppliers

China 25 Germany 1 South Korea 1 Switzerland 1 United States 4 Global 32

SIGMA-RBI

Tel: --
Fax: --
Country: Switzerland
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View Lastest Price from PROSTAGLANDINS F2ALPHA METHYL ESTER manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD

Product: Carboprost Impurity 9 33854-16-9
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 0.98
Supply Ability: 10g
Release date: 2024-04-25

33854-16-9, PROSTAGLANDINS F2ALPHA METHYL ESTERRelated Search:

Tafluprost Prostaglandin E1 Prostaglandin F2a (Z)-7-[(1R,2R,3R,5S)-5-ACETOXY-3-HYDROXY-2-((E)-(S)-3-HYDROXY-OCT-1-ENYL)-CYCLOPENTYL]-HEPT-5-ENOIC ACID METHYL ESTER 15(S)-15-Methyl prostaglandin (Z)-7-[(1R,2R,3R,5S)-5-ACETOXY-2-((E)-(S)-3-HYDROXY-OCT-1-ENYL)-3-(TETRAHYDRO-PYAN-2-YLOXY)-CYCLOPENTYL]-HEPT-5-ENOIC ACID METHYL ESTER 9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, ISOPROPYL ESTER PROSTAGLANDINS F2ALPHA METHYL ESTER 9ALPHA-11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1-GLYCERYL ESTER

(5Z,9S,11S,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic acid methyl ester

9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, METHYL ESTER

PGF2ALPHA-OME

PROSTAGLANDINS F2ALPHA METHYL ESTER

PROSTAGLANDIN F2ALPHA METHYL ESTER

Dinoprost methyl

PGF2a methyl

PJDMFGSFLLCCAO-NVRZHKMMSA-N

(5Z,13E,15S)-9α,11α,15-Trihydroxyprosta-5,13-dien-1-oic acid methyl ester

(Z)-Methyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)cyclopentyl)hept-5-enoate

13e,15s)-alph

9,11,15-trihydroxy-,methylester,(5z,9-alpha,11-prosta-13-dien-1-oicacid

dinoprostmethylester

pgf2-alphamethylester

pgf2methylester

prostaglandinf2methylester

prostaglandin F2A methyl ester

ProspaglandinF2alphamethylester

Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, methyl ester, (5Z,9α,11α,13E,15S)-

Prostaglandin F2α methyl ester

Carboprost Impurity 9

Prostaglandin F<sub>2α</sub> methyl ester

33854-16-9

BioChemical

Biochemicals and Reagents

Lipids

Prostaglandins

Fatty Acids

Arachidonic Acid Cascade

Fatty Acids

Lipids in Cell Signaling

Prostaglandins

ProstaglandinsLipids