2-AMINO-4-CHLORO-6-TRIFLUOROMETHYL-PYRIMIDINE

Product Name: 2-AMINO-4-CHLORO-6-TRIFLUOROMETHYL-PYRIMIDINE
CAS No.: 16097-60-2
Chemical Name: 2-AMINO-4-CHLORO-6-TRIFLUOROMETHYL-PYRIMIDINE
Synonyms: 4-chloro-6-(trifluoromethyl)pyrimidin-2-amine;4-Chloro-6-(TrifluoroMethyl)-2-PyriMidinaMine;2-AMINO-4-CHLORO-6-TRIFLUOROMETHYL-PYRIMIDINE;2-Pyrimidinamine, 4-chloro-6-(trifluoromethyl)-;4-CHLORO-6-(TRIFLUOROMETHYL)PYRIMIDIN-2-YLAMINE;PYRIMIDINE, 2-AMINO-4-CHLORO-6-(TRIFLUOROMETHYL)-;2-AMINO-4-CHLORO-6-TRIFLUOROMETHYL-PYRIMIDINE ISO 9001：2015 REACH
CBNumber: CB4330741
Molecular Formula: C5H3ClF3N3
Formula Weight: 197.55
MOL File: 16097-60-2.mol

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2-AMINO-4-CHLORO-6-TRIFLUOROMETHYL-PYRIMIDINE Property

Melting point:: 92-93 °C
Boiling point:: 280.7±50.0 °C(Predicted)
Density: 1.598±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 0.29±0.10(Predicted)
Appearance: White to off-white Solid
InChI: InChI=1S/C5H3ClF3N3/c6-3-1-2(5(7,8)9)11-4(10)12-3/h1H,(H2,10,11,12)
InChIKey: ZLIUVGFJXHOHLN-UHFFFAOYSA-N
SMILES: C1(N)=NC(C(F)(F)F)=CC(Cl)=N1

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Safety

HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: A612658
Product name: 2-Amino-4-chloro-6-trifluoromethyl-pyrimidine
Packaging: 2.5g
Price: $130
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-7-1V
Product name: 2-Amino-4-chloro-6-(trifluoromethyl)pyrimidine
Purity: 98%
Packaging: 1g
Price: $144
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0049727
Product name: 2-AMINO-4-CHLORO-6-(TRIFLUOROMETHYL)PYRIMIDINE
Purity: 95.00%
Packaging: 1G
Price: $166.95
Updated: 2021/12/16

AK Scientific

Product number: Y3198
Product name: 2-Amino-4-chloro-6-(trifluoromethyl)pyrimidine
Packaging: 10g
Price: $193
Updated: 2021/12/16

Apolloscientific

Product number: PC904758
Product name: 2-Amino-4-chloro-6-(trifluoromethyl)pyrimidine
Purity: 98%
Packaging: 5g
Price: $240
Updated: 2021/12/16

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2-AMINO-4-CHLORO-6-TRIFLUOROMETHYL-PYRIMIDINE Chemical Properties,Usage,Production

Synthesis

1513-69-5

16097-60-2

Example 15: Synthesis of 4-chloro-6-(trifluoromethyl)pyrimidin-2-amine (24) 2-Amino-6-(trifluoromethyl)pyrimidin-4-ol (200 mg, 1.1 mmol) was dissolved in a mixed solution of phosphorus oxychloride (POCl3, 3 eq., 0.3 mL, 3.3 mmol) and N,N-dimethylaniline (0.28 mL, 2 eq.). The reaction mixture was heated with stirring at 70 °C for 4 hours. Upon completion of the reaction, the mixture was slowly poured into an ice-water mixture to quench the reaction and the precipitated solid was collected by filtration to afford the target compound 24 in 59% yield. The product was identified by electrospray ionization mass spectrometry (ESI-MS), m/z 198 [M + H]+.

References

[1] Chinese Chemical Letters, 2013, vol. 24, # 5, p. 386 - 388
[2] Pesticide Science, 1999, vol. 55, # 5, p. 566 - 570
[3] Patent: WO2006/114409, 2006, A1. Location in patent: Page/Page column 23
[4] Patent: US2010/167935, 2010, A1. Location in patent: Page/Page column 24
[5] Journal of Medicinal Chemistry, 2014, vol. 57, # 6, p. 2429 - 2439

2-AMINO-4-CHLORO-6-TRIFLUOROMETHYL-PYRIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-4-CHLORO-6-TRIFLUOROMETHYL-PYRIMIDINE Suppliers

China 62 India 2 United States 8 Global 72

Nanjing YiFan Biological Technology Co., Ltd.

Tel: 025-025-52700520 18914499889
Fax: 025-52700520
Email: sales@yfbiotech.com
Country: China
ProdList: 495
Advantage: 58

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
ProdList: 5691
Advantage: 66

Shanghai Ennopharm Co., Ltd.

Tel: +86 (21) 6435-5022
Country: China
ProdList: 4267
Advantage: 65

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

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View Lastest Price from 2-AMINO-4-CHLORO-6-TRIFLUOROMETHYL-PYRIMIDINE manufacturers

Dideu Industries Group Limited

Product: 2-AMINO-4-CHLORO-6-TRIFLUOROMETHYL-PYRIMIDINE 16097-60-2
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-07

Career Henan Chemical Co

Product: 2-AMINO-4-CHLORO-6-TRIFLUOROMETHYL-PYRIMIDINE 16097-60-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-01-08

16097-60-2, 2-AMINO-4-CHLORO-6-TRIFLUOROMETHYL-PYRIMIDINERelated Search:

5-AMINO-6-CHLORO-2-(TRIFLUOROMETHYL)PYRIMIDINE-4-THIOL CHEMBRDG-BB 4015979 4-chloro-N-ethyl-6-(trifluoromethyl)-2-pyrimidinamine CHEMBRDG-BB 4015980 2-AMINO-4-CHLORO-6-TRIFLUOROMETHYL-PYRIMIDINE 4-Chloro-6-trifluoromethylpyrimidine

PYRIMIDINE, 2-AMINO-4-CHLORO-6-(TRIFLUOROMETHYL)-

4-CHLORO-6-(TRIFLUOROMETHYL)PYRIMIDIN-2-YLAMINE

2-AMINO-4-CHLORO-6-TRIFLUOROMETHYL-PYRIMIDINE

4-Chloro-6-(TrifluoroMethyl)-2-PyriMidinaMine

4-chloro-6-(trifluoromethyl)pyrimidin-2-amine

2-Pyrimidinamine, 4-chloro-6-(trifluoromethyl)-

2-AMINO-4-CHLORO-6-TRIFLUOROMETHYL-PYRIMIDINE ISO 9001：2015 REACH

16097-60-2

C5H3ClF3N3

Fluorine series

Building Blocks

Pyrimidine