CB-7921220 Property

Melting point:

225-226 °C

Boiling point:

504.3±50.0 °C(Predicted)

Density 

1.329±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

solubility 

DMF: 30 mg/ml; DMSO: 30 mg/ml; PBS (pH 7.2): 0.3 mg/ml

form 

A crystalline solid

pka

1.01±0.50(Predicted)

color 

Pink to red

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

CB-7921220 Chemical Properties,Usage,Production

Description

CB-7921220 is an inhibitor of the adenylyl cyclase (AC) isoforms AC1 and AC6. It is selective, reducing AC1 and AC6 activity by 60% while having no effect on AC2 and AC5 in Sf9 membranes stimulated by forskolin when used at a concentration of 100 μM.