H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
- Product Name
- H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
- CAS No.
- 229961-08-4
- Chemical Name
- H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
- Synonyms
- APELIN 12;RPRLSHKGPMPF;Apelin 12 - 1 mg;Apelin-12,(Des-Gln1)-Apelin-13;APELIN-12 (HUMAN, BOVINE, MOUSE, RAT);ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE;PREPROAPELIN (66-77) (HUMAN, BOVINE, MOUSE, RAT);(DES-GLN1)-APELIN-13 (HUMAN, BOVINE, MOUSE, RAT);H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH;APELIN PRECURSOR (66-77) (HUMAN, BOVINE, MOUSE, RAT)
- CBNumber
- CB4333520
- Molecular Formula
- C64H103N21O14S
- Formula Weight
- 1422.7
- MOL File
- 229961-08-4.mol
H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Property
- RTECS
- CD7310000
- storage temp.
- -15°C
- form
- Lyophilized powder
- color
- White to off-white
- Sequence
- H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH
- InChIKey
- KIODTAJAFBDDGP-TZIGXLGFSA-N
N-Bromosuccinimide Price
- Product number
- 023484
- Product name
- Apelin 12
- Packaging
- 96Tests
- Price
- $809
- Updated
- 2021/12/16
- Product number
- FA109622
- Product name
- Apelin-12 (human, bovine, mouse, rat) H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH
- Packaging
- 1mg
- Price
- $109
- Updated
- 2021/12/16
- Product number
- FA109622
- Product name
- Apelin-12 (human, bovine, mouse, rat) H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH
- Packaging
- 2mg
- Price
- $189
- Updated
- 2021/12/16
- Product number
- orb364270
- Product name
- Apelin-12
- Purity
- > 95%
- Packaging
- 1mg
- Price
- $287.3
- Updated
- 2021/12/16
- Product number
- 3466CC
- Product name
- Apelin-12(human,bovine,mouse,rat)
- Packaging
- 2mg
- Price
- $305
- Updated
- 2021/12/16
H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Chemical Properties,Usage,Production
Uses
Apelin-12 is one of the most potent C-terminal fragments of the polypeptide that possesses a high affinity to orphan receptor APJ receptor. Apelin-12 is involved in the regulation of body fluid homeostasis and in the central control of feeding. Apelin-12 blocks HIV-1 entry through APJ receptor. Apelin-12 exerts neuroprotective effect[1][2][3].
IC 50
HIV-1
References
[1] Pisarenko OI, et al. Effects of structural analogues of apelin-12 in acute myocardial infarction in rats. J Pharmacol Pharmacother. 2013;4(3):198-203. DOI:10.4103/0976-500X.114600
[2] Pisarenko OI, et al. Apelin-12 and its structural analog enhance antioxidant defense in experimental myocardial ischemia and reperfusion. Mol Cell Biochem. 2014;391(1-2):241-250. DOI:10.1007/s11010-014-2008-4
[3] Liu DR, et al. Apelin-12 exerts neuroprotective effect against ischemia-reperfusion injury by inhibiting JNK and P38MAPK signaling pathway in mouse. Eur Rev Med Pharmacol Sci. 2018;22(12):3888-3895. Liu DR, et al. Apelin-12 exerts neuroprotective effect against ischemia-reperfusion injury by inhibiting JNK and P38MAPK signaling pathway in mouse. Eur Rev Med Pharmacol Sci. 2018;22(12):3888-3895. DOI:10.26355/eurrev_201806_15273
[4] Ohno S, et al. Apelin-12 stimulates acid secretion through an increase of histamine release in rat stomachs. Regul Pept. 2012;174(1-3):71-78. DOI:10.1016/j.regpep.2011.12.002
H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH manufacturers
- Product
- H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH 229961-08-4
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-02-16
- Product
- H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH 229961-08-4
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-02-16