PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH

Product Name: PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
CAS No.: 217082-60-5
Chemical Name: PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH
Synonyms: Pyr-apelin-13;[PYR1]-APELIN-13;(Glp1)-Apelin-13;[pGlu1]-Apelin-13;{Glp}-RPRLSHKGPMPF;PYR-RPRLSHKGPMPF-OH;3-Dimethyluric acid;[PE]APELIN-13, HUMAN, BOVINE;(GLP1)-APELIN-13, HUMAN, BOVINE;(PYR1)-APELIN-13 (HUMAN, BOVINE)
CBNumber: CB1113712
Molecular Formula: C69H108N22O16S
Formula Weight: 1533.8
MOL File: 217082-60-5.mol

More

Less

PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Property

Density: 1.51±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
pka: 3.56±0.10(Predicted)
form: Powder
color: White to off-white
Water Solubility: Soluble to 1 mg/ml in sterile water
Sequence: Pyr-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Alfa Aesar

Product number: J66114
Product name: [Glp1]-Apelin-13, human, bovine
Packaging: 0.5mg
Price: $69.7
Updated: 2021/12/16

Alfa Aesar

Product number: J66114
Product name: [Glp1]-Apelin-13, human, bovine
Packaging: 1mg
Price: $94.3
Updated: 2021/12/16

Cayman Chemical

Product number: 15590
Product name: (Glp1)-Apelin-13
Purity: ≥95%
Packaging: 1mg
Price: $109
Updated: 2021/12/16

Tocris

Product number: 2420
Product name: [Pyr1]-Apelin-13
Packaging: 1
Price: $192
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FP109298
Product name: (Pyr 1)-Apelin-13
Packaging: 2mg
Price: $273
Updated: 2021/12/16

More

Less

PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Chemical Properties,Usage,Production

Uses

The apelin gene encodes a pre-proprotein that is processed to generate bioactive peptides consisting of 36, 17, or 13 amino acids: apelin-36 , apelin-17, and apelin-13 , respectively. Apelin-13 is an endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC50 value of 0.37 nM. (Glp1)-Apelin-13 is a pyroglutamylated form of apelin-13, in that the N-terminal glutamine residue is cyclized to pyroglutamic acid. Like apelin-13, this compound is a potent APJ receptor agonist (EC50 = 0.30 nM). (Glp1)-Apelin-13 is the major apelin isoform in the plasma of healthy human subjects. It can have vasoconstrictor and antipyretic effects in vitro and in vivo.

Definition

ChEBI: P-Glu-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe is a thirteen-membered polypeptide consisting of p-Glu, Arg, Pro, Arg, Leu, Ser, His, Lys, Gly, Pro, Met, Pro and Phe residues joined in sequence. It has a role as an apoptosis inhibitor, a neuroprotective agent and a human metabolite. It is a tautomer of a [Pyr1]apelin-13(2+).

storage

Store at -20°C

PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Suppliers

China 105 France 1 Germany 1 Japan 2 The Netherlands 1 United Kingdom 2 United States 15 USA 1 Global 128

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Cellmano Biotech Limited

Tel: 0551-65326643 18156095617
Fax: 0551-65326641
Email: info@cellmano.com
Country: China
ProdList: 1011
Advantage: 55

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Shanghai Witofly Chemical Co.,Ltd

Tel
Email: sales@witofly.com
Country: China
ProdList: 2864
Advantage: 52

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7783
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41462
Advantage: 60

More

Less

View Lastest Price from PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH manufacturers

Career Henan Chemical Co

Product: PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH 217082-60-5
Price: US $3.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2019-07-11

217082-60-5, PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OHRelated Search:

Chromium picolinate H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH

(GLP1)-APELIN-13, HUMAN, BOVINE

GLP-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE

(Glp1)-Apelin-13

5-Oxo-L-prolyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine

Pyr-apelin-13

GLP-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE: GRPRLSHKGPMPF

[PE]APELIN-13, HUMAN, BOVINE

PYR-RPRLSHKGPMPF-OH

PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE

PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH

[PYR1]-APELIN-13

(PYR1)-APELIN-13 (HUMAN, BOVINE)

(PYR1)-APELIN-13 (HUMAN, BOVINE, MOUSE, RAT)

[PGLU1]APELIN (24-36), HUMAN, BOVINE

PGLU-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE

[Pyr1]-Apelin-13,XRPRLSHKGPMPF,[pGlu1]-Apelin-13, >98%

[pGlu1]-Apelin-13

L-Phenylalanine, 5-oxo-L-prolyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-

PYR-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH USP/EP/BP

3-Dimethyluric acid

(Pyr?)-Apelin-13 (human, bovine, mouse, rat) acetate salt

[Pyr1]-Apelin-13 trifluoroacetate salt

{Glp}-RPRLSHKGPMPF

[Pyr1]-Apelin 13, endogenous apelin receptor (APJ) agonist

217082-60-5

C69H108N22O16S

peptide